Home
›
Interleukin 17F (IL17F)
Interleukin 17F (IL17F)
ML-1
IL-17F has been shown to stimulate prolifertion and activation of T cells and PBMCs, to inhibit angiogenesis as well as to regulate cartilage matrix turnover. This recombinant IL-17F is a homodimeric protein with a total weight of 30.1kDa containing two 134 amino acid residue chains.Using nested RACE PCR with leukocyte-anchored cDNA, Starnes et al. (2001) isolated an IL17F cDNA encoding a 153-amino acid protein that shares 40% homology with IL17.
In addition to the 2 invariant disulfide bonds found in other members of the IL17 family, IL17F contains a signal peptide with an extra cys-cys pair that could function as an extra disulfide bond. Expression of IL17F could not be identified by Northern blot analysis. RT-PCR analysis detected expression in activated, but not resting, CD4+ T cells and activated monocytes.
Organism species: Homo sapiens (Human)
Organism species: Mus musculus (Mouse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
U887Mu01
Recombinant Interleukin 17F (IL17F) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Interleukin 17F (IL17F) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Interleukin 17F (IL17F) WB; IHC; ICC; IP.
PU887Mu01
Polyclonal Antibody to Interleukin 17F (IL17F) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Interleukin 17F (IL17F) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Interleukin 17F (IL17F) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Interleukin 17F (IL17F) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Interleukin 17F (IL17F) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Interleukin 17F (IL17F) Flow Cytometry;ICC/IF
Assay Kits
KEU887Mu
ELISA Kit for Interleukin 17F (IL17F) Enzyme-linked immunosorbent assay for Antigen Detection
KCU887Mu
CLIA kit for Interleukin 17F (IL17F) CLIA assay for Antigen Detection
Organism species: Rattus norvegicus (Rat)
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Interleukin 17F (IL17F) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Interleukin 17F (IL17F) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Interleukin 17F (IL17F) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Interleukin 17F (IL17F) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Interleukin 17F (IL17F) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Interleukin 17F (IL17F) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Interleukin 17F (IL17F) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Interleukin 17F (IL17F) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Interleukin 17F (IL17F) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Interleukin 17F (IL17F) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Interleukin 17F (IL17F) CLIA assay for Antigen Detection
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Interleukin 17F (IL17F) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Interleukin 17F (IL17F) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Interleukin 17F (IL17F) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Interleukin 17F (IL17F) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Interleukin 17F (IL17F) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Interleukin 17F (IL17F) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Interleukin 17F (IL17F) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Interleukin 17F (IL17F) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Interleukin 17F (IL17F) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Interleukin 17F (IL17F) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Interleukin 17F (IL17F) CLIA assay for Antigen Detection
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Interleukin 17F (IL17F) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Interleukin 17F (IL17F) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Interleukin 17F (IL17F) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Interleukin 17F (IL17F) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Interleukin 17F (IL17F) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Interleukin 17F (IL17F) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Interleukin 17F (IL17F) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Interleukin 17F (IL17F) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Interleukin 17F (IL17F) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Interleukin 17F (IL17F) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Interleukin 17F (IL17F) CLIA assay for Antigen Detection
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Interleukin 17F (IL17F) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Interleukin 17F (IL17F) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Interleukin 17F (IL17F) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Interleukin 17F (IL17F) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Interleukin 17F (IL17F) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Interleukin 17F (IL17F) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Interleukin 17F (IL17F) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Interleukin 17F (IL17F) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Interleukin 17F (IL17F) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Interleukin 17F (IL17F) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Interleukin 17F (IL17F) CLIA assay for Antigen Detection
Organism species: Chicken (Gallus)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Interleukin 17F (IL17F) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Interleukin 17F (IL17F) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Interleukin 17F (IL17F) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Interleukin 17F (IL17F) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Interleukin 17F (IL17F) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Interleukin 17F (IL17F) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Interleukin 17F (IL17F) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Interleukin 17F (IL17F) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Interleukin 17F (IL17F) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Interleukin 17F (IL17F) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Interleukin 17F (IL17F) CLIA assay for Antigen Detection
Organism species: Ovis aries; Ovine (Sheep)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Interleukin 17F (IL17F) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Interleukin 17F (IL17F) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Interleukin 17F (IL17F) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Interleukin 17F (IL17F) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Interleukin 17F (IL17F) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Interleukin 17F (IL17F) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Interleukin 17F (IL17F) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Interleukin 17F (IL17F) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Interleukin 17F (IL17F) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Interleukin 17F (IL17F) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Interleukin 17F (IL17F) CLIA assay for Antigen Detection
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Interleukin 17F (IL17F) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Interleukin 17F (IL17F) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Interleukin 17F (IL17F) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Interleukin 17F (IL17F) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Interleukin 17F (IL17F) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Interleukin 17F (IL17F) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Interleukin 17F (IL17F) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Interleukin 17F (IL17F) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Interleukin 17F (IL17F) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Interleukin 17F (IL17F) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Interleukin 17F (IL17F) CLIA assay for Antigen Detection
Organism species: Cavia (Guinea pig )
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Interleukin 17F (IL17F) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Interleukin 17F (IL17F) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Interleukin 17F (IL17F) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Interleukin 17F (IL17F) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Interleukin 17F (IL17F) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Interleukin 17F (IL17F) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Interleukin 17F (IL17F) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Interleukin 17F (IL17F) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Interleukin 17F (IL17F) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Interleukin 17F (IL17F) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Interleukin 17F (IL17F) CLIA assay for Antigen Detection
Organism species: Equus caballus; Equine (Horse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Interleukin 17F (IL17F) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Interleukin 17F (IL17F) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Interleukin 17F (IL17F) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Interleukin 17F (IL17F) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Interleukin 17F (IL17F) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Interleukin 17F (IL17F) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Interleukin 17F (IL17F) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Interleukin 17F (IL17F) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Interleukin 17F (IL17F) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Interleukin 17F (IL17F) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Interleukin 17F (IL17F) CLIA assay for Antigen Detection
Organism species: Capra hircus; Caprine (Goat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Interleukin 17F (IL17F) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Interleukin 17F (IL17F) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Interleukin 17F (IL17F) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Interleukin 17F (IL17F) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Interleukin 17F (IL17F) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Interleukin 17F (IL17F) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Interleukin 17F (IL17F) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Interleukin 17F (IL17F) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Interleukin 17F (IL17F) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Interleukin 17F (IL17F) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Interleukin 17F (IL17F) CLIA assay for Antigen Detection
Organism species: Pan-species (General)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Interleukin 17F (IL17F) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Interleukin 17F (IL17F) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Interleukin 17F (IL17F) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Interleukin 17F (IL17F) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Interleukin 17F (IL17F) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Interleukin 17F (IL17F) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Interleukin 17F (IL17F) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Interleukin 17F (IL17F) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Interleukin 17F (IL17F) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Interleukin 17F (IL17F) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Interleukin 17F (IL17F) CLIA assay for Antigen Detection
Reference
"IL-17F, a novel cytokine selectively expressed in activated T cells and monocytes, regulates angiogenesis and endothelial cell cytokine production." J. Immunol. 167:4137-4140(2001) [PubMed ] [Europe PMC ] [Abstract ]
"The DNA sequence and analysis of human chromosome 6." Nature 425:805-811(2003) [PubMed ] [Europe PMC ] [Abstract ]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." Genome Res. 14:2121-2127(2004) [PubMed ] [Europe PMC ] [Abstract ]
"Identification of a novel cytokine, ML-1, and its expression in subjects with asthma." J. Immunol. 167:4430-4435(2001) [PubMed ] [Europe PMC ] [Abstract ]
"Signal peptide prediction based on analysis of experimentally verified cleavage sites." Protein Sci. 13:2819-2824(2004) [PubMed ] [Europe PMC ] [Abstract ]
"IL-17s adopt a cystine knot fold: structure and activity of a novel cytokine, IL-17F, and implications for receptor binding." EMBO J. 20:5332-5341(2001) [PubMed ] [Europe PMC ] [Abstract ]
"Structural basis of receptor sharing by interleukin 17 cytokines." Nat. Immunol. 10:1245-1251(2009) [PubMed ] [Europe PMC ] [Abstract ]
"Chronic mucocutaneous candidiasis in humans with inborn errors of interleukin-17 immunity." Science 332:65-68(2011) [PubMed ] [Europe PMC ] [Abstract ]
