Calpain 1, Large Subunit (CAPN1)
PIG30; CANPL1; MuCANP; MuCL; Calpain-1 Catalytic Subunit; Calcium-Dependent Protease 1; Calcium-activated neutral proteinase 1; Calpain mu-type; Micromolar-calpain
Calpain (calcium-dependent protease) is an intracellular protease that requires calcium for its catalytic activity. Two isozymes, calpain I (mu-calpain) and calpain II (m-calpain), with different calcium requirements, have been identified. Both are heterodimers composed of L (large, catalytic, 80 kD) and S (small, regulatory, 30 kD) subunits. The isozymes share an identical S subunit (CAPNS1), with the differences arising from the L subunits, L1 (CAPN1) and L2 (CAPN2). The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. Calpain-1 catalytic subunit is the large subunit of the ubiquitous enzyme, calpain 1.
Organism species: Homo sapiens (Human)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPU878Hu01 | Recombinant Calpain 1, Large Subunit (CAPN1) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAU878Hu01 | Monoclonal Antibody to Calpain 1, Large Subunit (CAPN1) | WB; IHC; ICC; IP. |
PAU878Hu01 | Polyclonal Antibody to Calpain 1, Large Subunit (CAPN1) | WB; IHC; ICC; IF. | |
Assay Kits | CLU878Hu01 | CLIA Kit for Calpain 1, Large Subunit (CAPN1) | CLIA assay for Antigen Detection |
ELU878Hu01 | ELISA Kit for Calpain 1, Large Subunit (CAPN1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPU878Mu01 | Recombinant Calpain 1, Large Subunit (CAPN1) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAU878Mu01 | Monoclonal Antibody to Calpain 1, Large Subunit (CAPN1) | WB; IHC; ICC; IP. |
PAU878Mu01 | Polyclonal Antibody to Calpain 1, Large Subunit (CAPN1) | WB; IHC; ICC; IF. | |
Assay Kits | CLU878Mu01 | CLIA Kit for Calpain 1, Large Subunit (CAPN1) | CLIA assay for Antigen Detection |
ELU878Mu01 | ELISA Kit for Calpain 1, Large Subunit (CAPN1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPU878Ra01 | Recombinant Calpain 1, Large Subunit (CAPN1) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAU878Ra01 | Monoclonal Antibody to Calpain 1, Large Subunit (CAPN1) | WB; IHC; ICC; IP. |
PAU878Ra01 | Polyclonal Antibody to Calpain 1, Large Subunit (CAPN1) | WB; IHC; ICC; IF. | |
Assay Kits | CLU878Ra01 | CLIA Kit for Calpain 1, Large Subunit (CAPN1) | CLIA assay for Antigen Detection |
ELU878Ra01 | ELISA Kit for Calpain 1, Large Subunit (CAPN1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPU878Ca01 | Recombinant Calpain 1, Large Subunit (CAPN1) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAU878Ca01 | Monoclonal Antibody to Calpain 1, Large Subunit (CAPN1) | WB; IHC; ICC; IP. |
PAU878Ca01 | Polyclonal Antibody to Calpain 1, Large Subunit (CAPN1) | WB; IHC; ICC; IF. | |
Assay Kits | CLU878Ca01 | CLIA Kit for Calpain 1, Large Subunit (CAPN1) | CLIA assay for Antigen Detection |
ELU878Ca01 | ELISA Kit for Calpain 1, Large Subunit (CAPN1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPU878Po01 | Recombinant Calpain 1, Large Subunit (CAPN1) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAU878Po01 | Monoclonal Antibody to Calpain 1, Large Subunit (CAPN1) | WB; IHC; ICC; IP. |
PAU878Po01 | Polyclonal Antibody to Calpain 1, Large Subunit (CAPN1) | WB; IHC; ICC; IF. | |
Assay Kits | CLU878Po01 | CLIA Kit for Calpain 1, Large Subunit (CAPN1) | CLIA assay for Antigen Detection |
ELU878Po01 | ELISA Kit for Calpain 1, Large Subunit (CAPN1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPU878Bo01 | Recombinant Calpain 1, Large Subunit (CAPN1) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAU878Bo01 | Monoclonal Antibody to Calpain 1, Large Subunit (CAPN1) | WB; IHC; ICC; IP. |
PAU878Bo01 | Polyclonal Antibody to Calpain 1, Large Subunit (CAPN1) | WB; IHC; ICC; IF. | |
Assay Kits | CLU878Bo01 | CLIA Kit for Calpain 1, Large Subunit (CAPN1) | CLIA assay for Antigen Detection |
ELU878Bo01 | ELISA Kit for Calpain 1, Large Subunit (CAPN1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPU878Rb01 | Recombinant Calpain 1, Large Subunit (CAPN1) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAU878Rb01 | Monoclonal Antibody to Calpain 1, Large Subunit (CAPN1) | WB; IHC; ICC; IP. |
PAU878Rb01 | Polyclonal Antibody to Calpain 1, Large Subunit (CAPN1) | WB; IHC; ICC; IF. | |
Assay Kits | CLU878Rb01 | CLIA Kit for Calpain 1, Large Subunit (CAPN1) | CLIA assay for Antigen Detection |
ELU878Rb01 | ELISA Kit for Calpain 1, Large Subunit (CAPN1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | RPU878Mo01 | Recombinant Calpain 1, Large Subunit (CAPN1) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAU878Mo01 | Monoclonal Antibody to Calpain 1, Large Subunit (CAPN1) | WB; IHC; ICC; IP. |
PAU878Mo01 | Polyclonal Antibody to Calpain 1, Large Subunit (CAPN1) | WB; IHC; ICC; IF. | |
Assay Kits | CLU878Mo01 | CLIA Kit for Calpain 1, Large Subunit (CAPN1) | CLIA assay for Antigen Detection |
ELU878Mo01 | ELISA Kit for Calpain 1, Large Subunit (CAPN1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Complete amino acid sequence of the large subunit of the low-Ca2+-requiring form of human Ca2+-activated neutral protease (muCANP) deduced from its cDNA sequence."
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