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Toll Like Receptor 8 (TLR8)
Toll Like Receptor 8 (TLR8)
CD288
Toll-like receptor 8 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity.
The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X.TLR8 recognises G-rich oligonucleotides.
Organism species: Homo sapiens (Human)
Organism species: Mus musculus (Mouse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Toll Like Receptor 8 (TLR8) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Toll Like Receptor 8 (TLR8) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Toll Like Receptor 8 (TLR8) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Toll Like Receptor 8 (TLR8) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Toll Like Receptor 8 (TLR8) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Toll Like Receptor 8 (TLR8) CLIA assay for Antigen Detection
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
U852Ra01
Recombinant Toll Like Receptor 8 (TLR8) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Toll Like Receptor 8 (TLR8) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Toll Like Receptor 8 (TLR8) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Toll Like Receptor 8 (TLR8) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Toll Like Receptor 8 (TLR8) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Toll Like Receptor 8 (TLR8) CLIA assay for Antigen Detection
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Toll Like Receptor 8 (TLR8) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Toll Like Receptor 8 (TLR8) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Toll Like Receptor 8 (TLR8) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Toll Like Receptor 8 (TLR8) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Toll Like Receptor 8 (TLR8) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Toll Like Receptor 8 (TLR8) CLIA assay for Antigen Detection
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Toll Like Receptor 8 (TLR8) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Toll Like Receptor 8 (TLR8) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Toll Like Receptor 8 (TLR8) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Toll Like Receptor 8 (TLR8) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Toll Like Receptor 8 (TLR8) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Toll Like Receptor 8 (TLR8) CLIA assay for Antigen Detection
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Toll Like Receptor 8 (TLR8) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Toll Like Receptor 8 (TLR8) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Toll Like Receptor 8 (TLR8) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Toll Like Receptor 8 (TLR8) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Toll Like Receptor 8 (TLR8) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Toll Like Receptor 8 (TLR8) CLIA assay for Antigen Detection
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Toll Like Receptor 8 (TLR8) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Toll Like Receptor 8 (TLR8) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Toll Like Receptor 8 (TLR8) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Toll Like Receptor 8 (TLR8) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Toll Like Receptor 8 (TLR8) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Toll Like Receptor 8 (TLR8) CLIA assay for Antigen Detection
Organism species: Chicken (Gallus)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Toll Like Receptor 8 (TLR8) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Toll Like Receptor 8 (TLR8) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Toll Like Receptor 8 (TLR8) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Toll Like Receptor 8 (TLR8) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Toll Like Receptor 8 (TLR8) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Toll Like Receptor 8 (TLR8) CLIA assay for Antigen Detection
Organism species: Ovis aries; Ovine (Sheep)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Toll Like Receptor 8 (TLR8) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Toll Like Receptor 8 (TLR8) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Toll Like Receptor 8 (TLR8) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Toll Like Receptor 8 (TLR8) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Toll Like Receptor 8 (TLR8) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Toll Like Receptor 8 (TLR8) CLIA assay for Antigen Detection
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Toll Like Receptor 8 (TLR8) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Toll Like Receptor 8 (TLR8) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Toll Like Receptor 8 (TLR8) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Toll Like Receptor 8 (TLR8) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Toll Like Receptor 8 (TLR8) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Toll Like Receptor 8 (TLR8) CLIA assay for Antigen Detection
Organism species: Cavia (Guinea pig )
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Toll Like Receptor 8 (TLR8) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Toll Like Receptor 8 (TLR8) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Toll Like Receptor 8 (TLR8) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Toll Like Receptor 8 (TLR8) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Toll Like Receptor 8 (TLR8) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Toll Like Receptor 8 (TLR8) CLIA assay for Antigen Detection
Organism species: Equus caballus; Equine (Horse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Toll Like Receptor 8 (TLR8) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Toll Like Receptor 8 (TLR8) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Toll Like Receptor 8 (TLR8) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Toll Like Receptor 8 (TLR8) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Toll Like Receptor 8 (TLR8) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Toll Like Receptor 8 (TLR8) CLIA assay for Antigen Detection
Organism species: Capra hircus; Caprine (Goat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Toll Like Receptor 8 (TLR8) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Toll Like Receptor 8 (TLR8) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Toll Like Receptor 8 (TLR8) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Toll Like Receptor 8 (TLR8) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Toll Like Receptor 8 (TLR8) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Toll Like Receptor 8 (TLR8) CLIA assay for Antigen Detection
Organism species: Pan-species (General)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Toll Like Receptor 8 (TLR8) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Toll Like Receptor 8 (TLR8) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Toll Like Receptor 8 (TLR8) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Toll Like Receptor 8 (TLR8) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Toll Like Receptor 8 (TLR8) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Toll Like Receptor 8 (TLR8) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Toll Like Receptor 8 (TLR8) CLIA assay for Antigen Detection
Reference
"Three novel mammalian Toll-like receptors: gene structure, expression, and evolution." PubMed ] [Europe PMC ] [Abstract ]
"Cloning and characterization of a sub-family of human Toll-like receptors: hTLR7, hTLR8 and hTLR9." PubMed ] [Europe PMC ] [Abstract ]
"Natural selection in the TLR-related genes in the course of primate evolution." Immunogenetics 60:727-735(2008) [PubMed ] [Europe PMC ] [Abstract ]
"The heterogeneous allelic repertoire of human Toll-Like receptor (TLR) genes." PLoS ONE 4:E7803-E7803(2009) [PubMed ] [Europe PMC ] [Abstract ]
"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed ] [Europe PMC ] [Abstract ]
"The DNA sequence of the human X chromosome." Nature 434:325-337(2005) [PubMed ] [Europe PMC ] [Abstract ]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." Genome Res. 14:2121-2127(2004) [PubMed ] [Europe PMC ] [Abstract ]
"Signaling by Toll-like receptors 8 and 9 requires Bruton's tyrosine kinase." J. Biol. Chem. 282:36953-36960(2007) [PubMed ] [Europe PMC ] [Abstract ]
"Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry." J. Proteome Res. 8:651-661(2009) [PubMed ] [Europe PMC ] [Abstract ]
"Structural reorganization of the Toll-like receptor 8 dimer induced by agonistic ligands." Science 339:1426-1429(2013) [PubMed ] [Europe PMC ] [Abstract ]
