Apolipoprotein C2 (APOC2)
APC2; Apo-C2; ProapoC-II; Apolipoprotein C-II; Proapolipoprotein C-II
Apolipoprotein C2 is secreted in plasma where it is a component of very low density lipoprotein. This protein activates the enzyme lipoprotein lipase, which hydrolyzes triglycerides and thus provides free fatty acids for cells. Mutations in this gene cause hyperlipoproteinemia type IB, characterized by hypertriglyceridemia, xanthomas, and increased risk of pancreatitis and early atherosclerosis. Apolipoprotein C-II (apoC-II) is a necessary cofactor for the activation of lipoprotein lipase (LPL), the enzyme that hydrolyzes triglycerides in plasma and transfers the fatty acids to tissues.The APOC2 cDNA sequence encodes a deduced 79-amino acid protein. Using synthetic oligonucleotides as probes, Sakaguchi et al. (1984) isolated APOC2 from a human cDNA library.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU847Hu01 | Recombinant Apolipoprotein C2 (APOC2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU847Hu01 | Monoclonal Antibody to Apolipoprotein C2 (APOC2) | WB; IHC; ICC; IP. |
| PAU847Hu01 | Polyclonal Antibody to Apolipoprotein C2 (APOC2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU847Hu01 | CLIA Kit for Apolipoprotein C2 (APOC2) | CLIA assay for Antigen Detection |
| ELU847Hu01 | ELISA Kit for Apolipoprotein C2 (APOC2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU847Mu01 | Recombinant Apolipoprotein C2 (APOC2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU847Mu01 | Monoclonal Antibody to Apolipoprotein C2 (APOC2) | WB; IHC; ICC; IP. |
| PAU847Mu01 | Polyclonal Antibody to Apolipoprotein C2 (APOC2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU847Mu01 | CLIA Kit for Apolipoprotein C2 (APOC2) | CLIA assay for Antigen Detection |
| ELU847Mu01 | ELISA Kit for Apolipoprotein C2 (APOC2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU847Ra01 | Recombinant Apolipoprotein C2 (APOC2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU847Ra01 | Monoclonal Antibody to Apolipoprotein C2 (APOC2) | WB; IHC; ICC; IP. |
| PAU847Ra01 | Polyclonal Antibody to Apolipoprotein C2 (APOC2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU847Ra01 | CLIA Kit for Apolipoprotein C2 (APOC2) | CLIA assay for Antigen Detection |
| ELU847Ra01 | ELISA Kit for Apolipoprotein C2 (APOC2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU847Ca01 | Recombinant Apolipoprotein C2 (APOC2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU847Ca01 | Monoclonal Antibody to Apolipoprotein C2 (APOC2) | WB; IHC; ICC; IP. |
| PAU847Ca01 | Polyclonal Antibody to Apolipoprotein C2 (APOC2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU847Ca01 | CLIA Kit for Apolipoprotein C2 (APOC2) | CLIA assay for Antigen Detection |
| ELU847Ca01 | ELISA Kit for Apolipoprotein C2 (APOC2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU847Po01 | Recombinant Apolipoprotein C2 (APOC2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU847Po01 | Monoclonal Antibody to Apolipoprotein C2 (APOC2) | WB; IHC; ICC; IP. |
| PAU847Po01 | Polyclonal Antibody to Apolipoprotein C2 (APOC2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU847Po01 | CLIA Kit for Apolipoprotein C2 (APOC2) | CLIA assay for Antigen Detection |
| ELU847Po01 | ELISA Kit for Apolipoprotein C2 (APOC2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU847Bo01 | Recombinant Apolipoprotein C2 (APOC2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU847Bo01 | Monoclonal Antibody to Apolipoprotein C2 (APOC2) | WB; IHC; ICC; IP. |
| PAU847Bo01 | Polyclonal Antibody to Apolipoprotein C2 (APOC2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU847Bo01 | CLIA Kit for Apolipoprotein C2 (APOC2) | CLIA assay for Antigen Detection |
| ELU847Bo01 | ELISA Kit for Apolipoprotein C2 (APOC2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU847Rb01 | Recombinant Apolipoprotein C2 (APOC2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU847Rb01 | Monoclonal Antibody to Apolipoprotein C2 (APOC2) | WB; IHC; ICC; IP. |
| PAU847Rb01 | Polyclonal Antibody to Apolipoprotein C2 (APOC2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU847Rb01 | CLIA Kit for Apolipoprotein C2 (APOC2) | CLIA assay for Antigen Detection |
| ELU847Rb01 | ELISA Kit for Apolipoprotein C2 (APOC2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU847Mo01 | Recombinant Apolipoprotein C2 (APOC2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU847Mo01 | Monoclonal Antibody to Apolipoprotein C2 (APOC2) | WB; IHC; ICC; IP. |
| PAU847Mo01 | Polyclonal Antibody to Apolipoprotein C2 (APOC2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU847Mo01 | CLIA Kit for Apolipoprotein C2 (APOC2) | CLIA assay for Antigen Detection |
| ELU847Mo01 | ELISA Kit for Apolipoprotein C2 (APOC2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
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"The human apolipoprotein C-II gene sequence contains a novel chromosome 19-specific minisatellite in its third intron."
J. Biol. Chem. 262:4787-4793(1987) [PubMed] [Europe PMC] [Abstract]
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Metabolism 61:906-921(2012) [PubMed] [Europe PMC] [Abstract]
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J. Proteome Res. 12:573-584(2013) [PubMed] [Europe PMC] [Abstract]
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Hum. Mol. Genet. 2:69-74(1993) [PubMed] [Europe PMC] [Abstract]
"An apolipoprotein CII mutation, CII Lys-19-->Thr identified in patients with hyperlipidemia."
Dis. Markers 9:73-80(1991) [PubMed] [Europe PMC] [Abstract]
"The apolipoprotein C-II variant apoC-II Lys-19-->Thr is not associated with dyslipidemia in an affected kindred."
Clin. Genet. 45:292-297(1994) [PubMed] [Europe PMC] [Abstract]
"A missense mutation (Trp 26-->Arg) in exon 3 of the apolipoprotein CII gene in a patient with apolipoprotein CII deficiency (apo CII-Wakayama)."
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