S100 Calcium Binding Protein A2 (S100A2)
S100-A2; CAN19; S100L
S100 proteins, such as S100A2, are small, acidic Ca(2+)-binding proteins that transduce Ca(2+)-signals via interaction with intracellular target proteins (Mandinova et al., 1998).
S100 calcium binding protein A2 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may have a tumor suppressor function. Chromosomal rearrangements and altered expression of this gene have been implicated in breast cancer.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU834Hu01 | Recombinant S100 Calcium Binding Protein A2 (S100A2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU834Hu01 | Monoclonal Antibody to S100 Calcium Binding Protein A2 (S100A2) | WB; IHC; ICC; IP. |
| PAU834Hu01 | Polyclonal Antibody to S100 Calcium Binding Protein A2 (S100A2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU834Hu01 | CLIA Kit for S100 Calcium Binding Protein A2 (S100A2) | CLIA assay for Antigen Detection |
| ELU834Hu01 | ELISA Kit for S100 Calcium Binding Protein A2 (S100A2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU834Mu01 | Recombinant S100 Calcium Binding Protein A2 (S100A2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU834Mu01 | Monoclonal Antibody to S100 Calcium Binding Protein A2 (S100A2) | WB; IHC; ICC; IP. |
| PAU834Mu01 | Polyclonal Antibody to S100 Calcium Binding Protein A2 (S100A2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU834Mu01 | CLIA Kit for S100 Calcium Binding Protein A2 (S100A2) | CLIA assay for Antigen Detection |
| ELU834Mu01 | ELISA Kit for S100 Calcium Binding Protein A2 (S100A2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU834Ra01 | Recombinant S100 Calcium Binding Protein A2 (S100A2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU834Ra01 | Monoclonal Antibody to S100 Calcium Binding Protein A2 (S100A2) | WB; IHC; ICC; IP. |
| PAU834Ra01 | Polyclonal Antibody to S100 Calcium Binding Protein A2 (S100A2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU834Ra01 | CLIA Kit for S100 Calcium Binding Protein A2 (S100A2) | CLIA assay for Antigen Detection |
| ELU834Ra01 | ELISA Kit for S100 Calcium Binding Protein A2 (S100A2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU834Ca01 | Recombinant S100 Calcium Binding Protein A2 (S100A2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU834Ca01 | Monoclonal Antibody to S100 Calcium Binding Protein A2 (S100A2) | WB; IHC; ICC; IP. |
| PAU834Ca01 | Polyclonal Antibody to S100 Calcium Binding Protein A2 (S100A2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU834Ca01 | CLIA Kit for S100 Calcium Binding Protein A2 (S100A2) | CLIA assay for Antigen Detection |
| ELU834Ca01 | ELISA Kit for S100 Calcium Binding Protein A2 (S100A2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU834Po01 | Recombinant S100 Calcium Binding Protein A2 (S100A2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU834Po01 | Monoclonal Antibody to S100 Calcium Binding Protein A2 (S100A2) | WB; IHC; ICC; IP. |
| PAU834Po01 | Polyclonal Antibody to S100 Calcium Binding Protein A2 (S100A2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU834Po01 | CLIA Kit for S100 Calcium Binding Protein A2 (S100A2) | CLIA assay for Antigen Detection |
| ELU834Po01 | ELISA Kit for S100 Calcium Binding Protein A2 (S100A2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU834Bo01 | Recombinant S100 Calcium Binding Protein A2 (S100A2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU834Bo01 | Monoclonal Antibody to S100 Calcium Binding Protein A2 (S100A2) | WB; IHC; ICC; IP. |
| PAU834Bo01 | Polyclonal Antibody to S100 Calcium Binding Protein A2 (S100A2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU834Bo01 | CLIA Kit for S100 Calcium Binding Protein A2 (S100A2) | CLIA assay for Antigen Detection |
| ELU834Bo01 | ELISA Kit for S100 Calcium Binding Protein A2 (S100A2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU834Rb01 | Recombinant S100 Calcium Binding Protein A2 (S100A2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU834Rb01 | Monoclonal Antibody to S100 Calcium Binding Protein A2 (S100A2) | WB; IHC; ICC; IP. |
| PAU834Rb01 | Polyclonal Antibody to S100 Calcium Binding Protein A2 (S100A2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU834Rb01 | CLIA Kit for S100 Calcium Binding Protein A2 (S100A2) | CLIA assay for Antigen Detection |
| ELU834Rb01 | ELISA Kit for S100 Calcium Binding Protein A2 (S100A2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU834Mo01 | Recombinant S100 Calcium Binding Protein A2 (S100A2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU834Mo01 | Monoclonal Antibody to S100 Calcium Binding Protein A2 (S100A2) | WB; IHC; ICC; IP. |
| PAU834Mo01 | Polyclonal Antibody to S100 Calcium Binding Protein A2 (S100A2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU834Mo01 | CLIA Kit for S100 Calcium Binding Protein A2 (S100A2) | CLIA assay for Antigen Detection |
| ELU834Mo01 | ELISA Kit for S100 Calcium Binding Protein A2 (S100A2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Down-regulation of a member of the S100 gene family in mammary carcinoma cells and reexpression by azadeoxycytidine treatment."
Proc. Natl. Acad. Sci. U.S.A. 89:2504-2508(1992) [PubMed] [Europe PMC] [Abstract]
"Repression of the candidate tumor suppressor gene S100A2 in breast cancer is mediated by site-specific hypermethylation."
Cell Calcium 22:243-254(1997) [PubMed] [Europe PMC] [Abstract]
"The DNA sequence and biological annotation of human chromosome 1."
Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Microsequences of 145 proteins recorded in the two-dimensional gel protein database of normal human epidermal keratinocytes."
Electrophoresis 13:960-969(1992) [PubMed] [Europe PMC] [Abstract]
"S100 proteins regulate the interaction of Hsp90 with cyclophilin 40 and FKBP52 through their tetratricopeptide repeats."
FEBS Lett. 584:1119-1125(2010) [PubMed] [Europe PMC] [Abstract]
"Initial characterization of the human central proteome."
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
"S100 proteins modulate protein phosphatase 5 function: a link between CA2+ signal transduction and protein dephosphorylation."
J. Biol. Chem. 287:13787-13798(2012) [PubMed] [Europe PMC] [Abstract]
"Crystal structure of Ca2+ -free S100A2 at 1.6-A resolution."
J. Mol. Biol. 378:933-942(2008) [PubMed] [Europe PMC] [Abstract]