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Keratin 8 (KRT8)

K8; CARD2; CK8; CYK8; K2C8; KO; Cytokeratin 8; Keratin, type II cytoskeletal 8

Keratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells.

This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.

The human and mouse CK8 share about 82% identity in the N-terminal head domain, 95% identity in the alpha helical rod domain, and 67.5% identity in the C-terminal tail.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU818Hu01 Recombinant Keratin 8 (KRT8) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU818Hu01 Monoclonal Antibody to Keratin 8 (KRT8) WB; IHC; ICC; IP.
PAU818Hu01 Polyclonal Antibody to Keratin 8 (KRT8) WB; IHC; ICC; IF.
Assay Kits CLU818Hu01 CLIA Kit for Keratin 8 (KRT8) CLIA assay for Antigen Detection
ELU818Hu01 ELISA Kit for Keratin 8 (KRT8) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU818Mu01 Recombinant Keratin 8 (KRT8) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU818Mu01 Monoclonal Antibody to Keratin 8 (KRT8) WB; IHC; ICC; IP.
PAU818Mu01 Polyclonal Antibody to Keratin 8 (KRT8) WB; IHC; ICC; IF.
Assay Kits CLU818Mu01 CLIA Kit for Keratin 8 (KRT8) CLIA assay for Antigen Detection
ELU818Mu01 ELISA Kit for Keratin 8 (KRT8) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU818Ra01 Recombinant Keratin 8 (KRT8) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU818Ra01 Monoclonal Antibody to Keratin 8 (KRT8) WB; IHC; ICC; IP.
PAU818Ra01 Polyclonal Antibody to Keratin 8 (KRT8) WB; IHC; ICC; IF.
Assay Kits CLU818Ra01 CLIA Kit for Keratin 8 (KRT8) CLIA assay for Antigen Detection
ELU818Ra01 ELISA Kit for Keratin 8 (KRT8) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU818Ca01 Recombinant Keratin 8 (KRT8) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU818Ca01 Monoclonal Antibody to Keratin 8 (KRT8) WB; IHC; ICC; IP.
PAU818Ca01 Polyclonal Antibody to Keratin 8 (KRT8) WB; IHC; ICC; IF.
Assay Kits CLU818Ca01 CLIA Kit for Keratin 8 (KRT8) CLIA assay for Antigen Detection
ELU818Ca01 ELISA Kit for Keratin 8 (KRT8) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU818Po01 Recombinant Keratin 8 (KRT8) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU818Po01 Monoclonal Antibody to Keratin 8 (KRT8) WB; IHC; ICC; IP.
PAU818Po01 Polyclonal Antibody to Keratin 8 (KRT8) WB; IHC; ICC; IF.
Assay Kits CLU818Po01 CLIA Kit for Keratin 8 (KRT8) CLIA assay for Antigen Detection
ELU818Po01 ELISA Kit for Keratin 8 (KRT8) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU818Bo01 Recombinant Keratin 8 (KRT8) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU818Bo01 Monoclonal Antibody to Keratin 8 (KRT8) WB; IHC; ICC; IP.
PAU818Bo01 Polyclonal Antibody to Keratin 8 (KRT8) WB; IHC; ICC; IF.
Assay Kits CLU818Bo01 CLIA Kit for Keratin 8 (KRT8) CLIA assay for Antigen Detection
ELU818Bo01 ELISA Kit for Keratin 8 (KRT8) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU818Rb01 Recombinant Keratin 8 (KRT8) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU818Rb01 Monoclonal Antibody to Keratin 8 (KRT8) WB; IHC; ICC; IP.
PAU818Rb01 Polyclonal Antibody to Keratin 8 (KRT8) WB; IHC; ICC; IF.
Assay Kits CLU818Rb01 CLIA Kit for Keratin 8 (KRT8) CLIA assay for Antigen Detection
ELU818Rb01 ELISA Kit for Keratin 8 (KRT8) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU818Mo01 Recombinant Keratin 8 (KRT8) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU818Mo01 Monoclonal Antibody to Keratin 8 (KRT8) WB; IHC; ICC; IP.
PAU818Mo01 Polyclonal Antibody to Keratin 8 (KRT8) WB; IHC; ICC; IF.
Assay Kits CLU818Mo01 CLIA Kit for Keratin 8 (KRT8) CLIA assay for Antigen Detection
ELU818Mo01 ELISA Kit for Keratin 8 (KRT8) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

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"O-GlcNAcylation determines the solubility, filament organization, and stability of keratins 8 and 18."
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"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
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