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Interleukin 29 (IL29)

FNL1; Interferon,Lambda 1; Cytokine Zcyto21

Interleukin-29 (IL-29) is a protein of the helical cytokine family and is a type III interferon. It is also known as IFN lambda1 and is highly similar in amino acid sequence to the IL-28, the other type III interferon.

IL-29 is a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 28B (IL28B) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA).

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU814Hu01 Recombinant Interleukin 29 (IL29) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU814Hu01 Monoclonal Antibody to Interleukin 29 (IL29) WB; IHC; ICC; IP.
PAU814Hu01 Polyclonal Antibody to Interleukin 29 (IL29) WB; IHC; ICC; IF.
Assay Kits CLU814Hu01 CLIA Kit for Interleukin 29 (IL29) CLIA assay for Antigen Detection
ELU814Hu01 ELISA Kit for Interleukin 29 (IL29) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU814Mu01 Recombinant Interleukin 29 (IL29) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU814Mu01 Monoclonal Antibody to Interleukin 29 (IL29) WB; IHC; ICC; IP.
PAU814Mu01 Polyclonal Antibody to Interleukin 29 (IL29) WB; IHC; ICC; IF.
Assay Kits CLU814Mu01 CLIA Kit for Interleukin 29 (IL29) CLIA assay for Antigen Detection
ELU814Mu01 ELISA Kit for Interleukin 29 (IL29) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU814Ra01 Recombinant Interleukin 29 (IL29) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU814Ra01 Monoclonal Antibody to Interleukin 29 (IL29) WB; IHC; ICC; IP.
PAU814Ra01 Polyclonal Antibody to Interleukin 29 (IL29) WB; IHC; ICC; IF.
Assay Kits CLU814Ra01 CLIA Kit for Interleukin 29 (IL29) CLIA assay for Antigen Detection
ELU814Ra01 ELISA Kit for Interleukin 29 (IL29) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU814Ca01 Recombinant Interleukin 29 (IL29) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU814Ca01 Monoclonal Antibody to Interleukin 29 (IL29) WB; IHC; ICC; IP.
PAU814Ca01 Polyclonal Antibody to Interleukin 29 (IL29) WB; IHC; ICC; IF.
Assay Kits CLU814Ca01 CLIA Kit for Interleukin 29 (IL29) CLIA assay for Antigen Detection
ELU814Ca01 ELISA Kit for Interleukin 29 (IL29) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU814Po01 Recombinant Interleukin 29 (IL29) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU814Po01 Monoclonal Antibody to Interleukin 29 (IL29) WB; IHC; ICC; IP.
PAU814Po01 Polyclonal Antibody to Interleukin 29 (IL29) WB; IHC; ICC; IF.
Assay Kits CLU814Po01 CLIA Kit for Interleukin 29 (IL29) CLIA assay for Antigen Detection
ELU814Po01 ELISA Kit for Interleukin 29 (IL29) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU814Bo01 Recombinant Interleukin 29 (IL29) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU814Bo01 Monoclonal Antibody to Interleukin 29 (IL29) WB; IHC; ICC; IP.
PAU814Bo01 Polyclonal Antibody to Interleukin 29 (IL29) WB; IHC; ICC; IF.
Assay Kits CLU814Bo01 CLIA Kit for Interleukin 29 (IL29) CLIA assay for Antigen Detection
ELU814Bo01 ELISA Kit for Interleukin 29 (IL29) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU814Rb01 Recombinant Interleukin 29 (IL29) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU814Rb01 Monoclonal Antibody to Interleukin 29 (IL29) WB; IHC; ICC; IP.
PAU814Rb01 Polyclonal Antibody to Interleukin 29 (IL29) WB; IHC; ICC; IF.
Assay Kits CLU814Rb01 CLIA Kit for Interleukin 29 (IL29) CLIA assay for Antigen Detection
ELU814Rb01 ELISA Kit for Interleukin 29 (IL29) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU814Mo01 Recombinant Interleukin 29 (IL29) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU814Mo01 Monoclonal Antibody to Interleukin 29 (IL29) WB; IHC; ICC; IP.
PAU814Mo01 Polyclonal Antibody to Interleukin 29 (IL29) WB; IHC; ICC; IF.
Assay Kits CLU814Mo01 CLIA Kit for Interleukin 29 (IL29) CLIA assay for Antigen Detection
ELU814Mo01 ELISA Kit for Interleukin 29 (IL29) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"IL-28, IL-29 and their class II cytokine receptor IL-28R."
Nat. Immunol. 4:63-68(2003) [PubMed] [Europe PMC] [Abstract]

"IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex."
Nat. Immunol. 4:69-77(2003) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence and biology of human chromosome 19."
Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Interferon-lambda: a new addition to an old family."
J. Interferon Cytokine Res. 30:555-564(2010) [PubMed] [Europe PMC] [Abstract]

"Interferon-lambda in the context of viral infections: production, response and therapeutic implications."
J. Innate Immun. 6:563-574(2014) [PubMed] [Europe PMC] [Abstract]

"Crystal structure of human interferon-lambda1 in complex with its high-affinity receptor interferon-lambdaR1."
J. Mol. Biol. 404:650-664(2010) [PubMed] [Europe PMC] [Abstract]