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Ki-67 Protein (Ki67P)

MKI67; KIA; Ki-67; Antigen Identified By Monoclonal Antibody Ki-67

The Ki-67 protein is a cellular marker for proliferation. It is strictly associated with cell proliferation. During interphase, the Ki-67 antigen can be exclusively detected within the cell nucleus, whereas in mitosis most of the protein is relocated to the surface of the chromosomes.

Ki-67 protein is present during all active phases of the cell cycle (G1, S, G2, and mitosis), but is absent from resting cells (G0).Ki-67 is an excellent marker to determine the growth fraction of a given cell population.

The fraction of Ki-67-positive tumor cells (the Ki-67 labelling index) is often correlated with the clinical course of cancer. The best-studied examples in this context are carcinomas of the prostate and the breast.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins U797Hu01 Recombinant Ki-67 Protein (Ki67P) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ki-67 Protein (Ki67P) Bioactivity
Antibodies MU797Hu22 Monoclonal Antibody to Ki-67 Protein (Ki67P) WB; IHC; ICC; IP.
PU797Hu01 Polyclonal Antibody to Ki-67 Protein (Ki67P) WB; IHC; ICC; IF.
LU797Hu71 Biotin Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) Flow Cytometry;ICC/IF
Assay Kits KEU797Hu ELISA Kit for Ki-67 Protein (Ki67P) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ki-67 Protein (Ki67P) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins U797Mu01 Recombinant Ki-67 Protein (Ki67P) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ki-67 Protein (Ki67P) Bioactivity
Antibodies NONE Monoclonal Antibody to Ki-67 Protein (Ki67P) WB; IHC; ICC; IP.
PU797Mu01 Polyclonal Antibody to Ki-67 Protein (Ki67P) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) Flow Cytometry;ICC/IF
Assay Kits KEU797Mu ELISA Kit for Ki-67 Protein (Ki67P) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ki-67 Protein (Ki67P) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins U797Ra01 Recombinant Ki-67 Protein (Ki67P) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ki-67 Protein (Ki67P) Bioactivity
Antibodies MU797Ra21 Monoclonal Antibody to Ki-67 Protein (Ki67P) WB; IHC; ICC; IP.
PU797Ra01 Polyclonal Antibody to Ki-67 Protein (Ki67P) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) Flow Cytometry;ICC/IF
Assay Kits KEU797Ra ELISA Kit for Ki-67 Protein (Ki67P) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ki-67 Protein (Ki67P) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ki-67 Protein (Ki67P) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ki-67 Protein (Ki67P) Bioactivity
Antibodies NONE Monoclonal Antibody to Ki-67 Protein (Ki67P) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ki-67 Protein (Ki67P) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ki-67 Protein (Ki67P) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ki-67 Protein (Ki67P) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ki-67 Protein (Ki67P) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ki-67 Protein (Ki67P) Bioactivity
Antibodies NONE Monoclonal Antibody to Ki-67 Protein (Ki67P) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ki-67 Protein (Ki67P) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ki-67 Protein (Ki67P) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ki-67 Protein (Ki67P) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ki-67 Protein (Ki67P) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ki-67 Protein (Ki67P) Bioactivity
Antibodies NONE Monoclonal Antibody to Ki-67 Protein (Ki67P) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ki-67 Protein (Ki67P) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ki-67 Protein (Ki67P) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ki-67 Protein (Ki67P) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ki-67 Protein (Ki67P) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ki-67 Protein (Ki67P) Bioactivity
Antibodies NONE Monoclonal Antibody to Ki-67 Protein (Ki67P) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ki-67 Protein (Ki67P) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ki-67 Protein (Ki67P) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ki-67 Protein (Ki67P) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ki-67 Protein (Ki67P) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ki-67 Protein (Ki67P) Bioactivity
Antibodies NONE Monoclonal Antibody to Ki-67 Protein (Ki67P) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ki-67 Protein (Ki67P) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ki-67 Protein (Ki67P) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ki-67 Protein (Ki67P) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ki-67 Protein (Ki67P) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ki-67 Protein (Ki67P) Bioactivity
Antibodies NONE Monoclonal Antibody to Ki-67 Protein (Ki67P) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ki-67 Protein (Ki67P) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ki-67 Protein (Ki67P) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ki-67 Protein (Ki67P) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ki-67 Protein (Ki67P) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ki-67 Protein (Ki67P) Bioactivity
Antibodies NONE Monoclonal Antibody to Ki-67 Protein (Ki67P) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ki-67 Protein (Ki67P) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ki-67 Protein (Ki67P) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ki-67 Protein (Ki67P) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ki-67 Protein (Ki67P) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ki-67 Protein (Ki67P) Bioactivity
Antibodies NONE Monoclonal Antibody to Ki-67 Protein (Ki67P) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ki-67 Protein (Ki67P) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ki-67 Protein (Ki67P) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ki-67 Protein (Ki67P) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ki-67 Protein (Ki67P) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ki-67 Protein (Ki67P) Bioactivity
Antibodies NONE Monoclonal Antibody to Ki-67 Protein (Ki67P) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ki-67 Protein (Ki67P) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ki-67 Protein (Ki67P) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ki-67 Protein (Ki67P) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ki-67 Protein (Ki67P) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ki-67 Protein (Ki67P) Bioactivity
Antibodies NONE Monoclonal Antibody to Ki-67 Protein (Ki67P) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ki-67 Protein (Ki67P) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ki-67 Protein (Ki67P) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ki-67 Protein (Ki67P) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ki-67 Protein (Ki67P) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ki-67 Protein (Ki67P) Bioactivity
Antibodies NONE Monoclonal Antibody to Ki-67 Protein (Ki67P) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ki-67 Protein (Ki67P) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ki-67 Protein (Ki67P) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ki-67 Protein (Ki67P) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ki-67 Protein (Ki67P) CLIA assay for Antigen Detection

Reference

"The cell proliferation-associated antigen of antibody Ki-67: a very large, ubiquitous nuclear protein with numerous repeated elements, representing a new kind of cell cycle-maintaining proteins."
J. Cell Biol. 123:513-522(1993) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence and comparative analysis of human chromosome 10."
Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]

"The forkhead-associated domain of Ki-67 antigen interacts with the novel kinesin-like protein Hklp2."
J. Biol. Chem. 275:28888-28892(2000) [PubMed] [Europe PMC] [Abstract]

"A novel nucleolar protein, NIFK, interacts with the forkhead associated domain of Ki-67 antigen in mitosis."
J. Biol. Chem. 276:25386-25391(2001) [PubMed] [Europe PMC] [Abstract]

"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]

"A probability-based approach for high-throughput protein phosphorylation analysis and site localization."
Nat. Biotechnol. 24:1285-1292(2006) [PubMed] [Europe PMC] [Abstract]

"Improved titanium dioxide enrichment of phosphopeptides from HeLa cells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra."
J. Proteome Res. 6:4150-4162(2007) [PubMed] [Europe PMC] [Abstract]

"Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis."
J. Proteome Res. 7:1346-1351(2008) [PubMed] [Europe PMC] [Abstract]

"Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."
Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]

"A quantitative atlas of mitotic phosphorylation."
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]

"Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]

"Identification and characterization of a novel nuclear protein complex involved in nuclear hormone receptor-mediated gene regulation."
J. Biol. Chem. 284:7542-7552(2009) [PubMed] [Europe PMC] [Abstract]

"Large-scale proteomics analysis of the human kinome."
Mol. Cell. Proteomics 8:1751-1764(2009) [PubMed] [Europe PMC] [Abstract]

"Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]

"Lysine acetylation targets protein complexes and co-regulates major cellular functions."
Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]

"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]

"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]

"Microcephaly gene links trithorax and REST/NRSF to control neural stem cell proliferation and differentiation."
Cell 151:1097-1112(2012) [PubMed] [Europe PMC] [Abstract]

"Systematic analysis of protein pools, isoforms, and modifications affecting turnover and subcellular localization."
Mol. Cell. Proteomics 11:M111.013680.01-M111.013680.15(2012) [PubMed] [Europe PMC] [Abstract]

"Structure of human Ki67 FHA domain and its binding to a phosphoprotein fragment from hNIFK reveal unique recognition sites and new views to the structural basis of FHA domain functions."
J. Mol. Biol. 335:371-381(2004) [PubMed] [Europe PMC] [Abstract]

"Sequential phosphorylation and multisite interactions characterize specific target recognition by the FHA domain of Ki67."
Nat. Struct. Mol. Biol. 12:987-993(2005) [PubMed] [Europe PMC] [Abstract]