Platelet Derived Growth Factor Receptor Beta (PDGFRb)
CD140b; JTK12; PDGF-R-Beta; PDGFR; PDGFR1; CD140 antigen-like family member B; Platelet-derived growth factor receptor 1; Beta-type platelet-derived growth factor receptor
PDGFRb is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.
Organism species: Homo sapiens (Human)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | U783Hu01 | Recombinant Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Positive Control; Immunogen; SDS-PAGE; WB. |
NONE | Native Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Bioactivity | |
Antibodies | MU783Hu22 | Monoclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | WB; IHC; ICC; IP. |
PU783Hu01 | Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | WB; IHC; ICC; IF. | |
NONE | Biotin Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | ELISA(Det);IC; IH; IH(P); WB | |
NONE | APC Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | IHC, WB | |
NONE | HRP Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Simple Western; WB | |
NONE | PE Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Flow Cytometry | |
NONE | FITC Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Flow Cytometry;ICC/IF | |
Assay Kits | KEU783Hu | ELISA Kit for Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Enzyme-linked immunosorbent assay for Antigen Detection |
NONE | CLIA kit for Platelet Derived Growth Factor Receptor Beta (PDGFRb) | CLIA assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | U783Mu01 | Recombinant Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Positive Control; Immunogen; SDS-PAGE; WB. |
NONE | Native Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Bioactivity | |
Antibodies | NONE | Monoclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | WB; IHC; ICC; IP. |
PU783Mu01 | Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | WB; IHC; ICC; IF. | |
NONE | Biotin Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | ELISA(Det);IC; IH; IH(P); WB | |
NONE | APC Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | IHC, WB | |
NONE | HRP Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Simple Western; WB | |
NONE | PE Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Flow Cytometry | |
NONE | FITC Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Flow Cytometry;ICC/IF | |
Assay Kits | NONE | ELISA Kit for Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Enzyme-linked immunosorbent assay for Antigen Detection |
NONE | CLIA kit for Platelet Derived Growth Factor Receptor Beta (PDGFRb) | CLIA assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | NONE | Recombinant Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Positive Control; Immunogen; SDS-PAGE; WB. |
NONE | Native Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Bioactivity | |
Antibodies | NONE | Monoclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | WB; IHC; ICC; IP. |
NONE | Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | WB; IHC; ICC; IF. | |
NONE | Biotin Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | ELISA(Det);IC; IH; IH(P); WB | |
NONE | APC Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | IHC, WB | |
NONE | HRP Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Simple Western; WB | |
NONE | PE Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Flow Cytometry | |
NONE | FITC Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Flow Cytometry;ICC/IF | |
Assay Kits | KEU783Ra | ELISA Kit for Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Enzyme-linked immunosorbent assay for Antigen Detection |
NONE | CLIA kit for Platelet Derived Growth Factor Receptor Beta (PDGFRb) | CLIA assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | NONE | Recombinant Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Positive Control; Immunogen; SDS-PAGE; WB. |
NONE | Native Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Bioactivity | |
Antibodies | NONE | Monoclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | WB; IHC; ICC; IP. |
NONE | Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | WB; IHC; ICC; IF. | |
NONE | Biotin Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | ELISA(Det);IC; IH; IH(P); WB | |
NONE | APC Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | IHC, WB | |
NONE | HRP Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Simple Western; WB | |
NONE | PE Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Flow Cytometry | |
NONE | FITC Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Flow Cytometry;ICC/IF | |
Assay Kits | NONE | ELISA Kit for Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Enzyme-linked immunosorbent assay for Antigen Detection |
NONE | CLIA kit for Platelet Derived Growth Factor Receptor Beta (PDGFRb) | CLIA assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | NONE | Recombinant Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Positive Control; Immunogen; SDS-PAGE; WB. |
NONE | Native Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Bioactivity | |
Antibodies | NONE | Monoclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | WB; IHC; ICC; IP. |
NONE | Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | WB; IHC; ICC; IF. | |
NONE | Biotin Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | ELISA(Det);IC; IH; IH(P); WB | |
NONE | APC Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | IHC, WB | |
NONE | HRP Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Simple Western; WB | |
NONE | PE Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Flow Cytometry | |
NONE | FITC Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Flow Cytometry;ICC/IF | |
Assay Kits | NONE | ELISA Kit for Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Enzyme-linked immunosorbent assay for Antigen Detection |
NONE | CLIA kit for Platelet Derived Growth Factor Receptor Beta (PDGFRb) | CLIA assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | NONE | Recombinant Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Positive Control; Immunogen; SDS-PAGE; WB. |
NONE | Native Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Bioactivity | |
Antibodies | NONE | Monoclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | WB; IHC; ICC; IP. |
NONE | Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | WB; IHC; ICC; IF. | |
NONE | Biotin Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | ELISA(Det);IC; IH; IH(P); WB | |
NONE | APC Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | IHC, WB | |
NONE | HRP Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Simple Western; WB | |
NONE | PE Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Flow Cytometry | |
NONE | FITC Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Flow Cytometry;ICC/IF | |
Assay Kits | NONE | ELISA Kit for Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Enzyme-linked immunosorbent assay for Antigen Detection |
NONE | CLIA kit for Platelet Derived Growth Factor Receptor Beta (PDGFRb) | CLIA assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | NONE | Recombinant Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Positive Control; Immunogen; SDS-PAGE; WB. |
NONE | Native Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Bioactivity | |
Antibodies | NONE | Monoclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | WB; IHC; ICC; IP. |
NONE | Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | WB; IHC; ICC; IF. | |
NONE | Biotin Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | ELISA(Det);IC; IH; IH(P); WB | |
NONE | APC Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | IHC, WB | |
NONE | HRP Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Simple Western; WB | |
NONE | PE Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Flow Cytometry | |
NONE | FITC Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Flow Cytometry;ICC/IF | |
Assay Kits | NONE | ELISA Kit for Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Enzyme-linked immunosorbent assay for Antigen Detection |
NONE | CLIA kit for Platelet Derived Growth Factor Receptor Beta (PDGFRb) | CLIA assay for Antigen Detection |
Organism species: Chicken (Gallus)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | NONE | Recombinant Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Positive Control; Immunogen; SDS-PAGE; WB. |
NONE | Native Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Bioactivity | |
Antibodies | NONE | Monoclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | WB; IHC; ICC; IP. |
NONE | Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | WB; IHC; ICC; IF. | |
NONE | Biotin Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | ELISA(Det);IC; IH; IH(P); WB | |
NONE | APC Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | IHC, WB | |
NONE | HRP Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Simple Western; WB | |
NONE | PE Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Flow Cytometry | |
NONE | FITC Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Flow Cytometry;ICC/IF | |
Assay Kits | NONE | ELISA Kit for Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Enzyme-linked immunosorbent assay for Antigen Detection |
NONE | CLIA kit for Platelet Derived Growth Factor Receptor Beta (PDGFRb) | CLIA assay for Antigen Detection |
Organism species: Ovis aries; Ovine (Sheep)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | NONE | Recombinant Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Positive Control; Immunogen; SDS-PAGE; WB. |
NONE | Native Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Bioactivity | |
Antibodies | NONE | Monoclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | WB; IHC; ICC; IP. |
NONE | Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | WB; IHC; ICC; IF. | |
NONE | Biotin Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | ELISA(Det);IC; IH; IH(P); WB | |
NONE | APC Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | IHC, WB | |
NONE | HRP Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Simple Western; WB | |
NONE | PE Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Flow Cytometry | |
NONE | FITC Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Flow Cytometry;ICC/IF | |
Assay Kits | NONE | ELISA Kit for Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Enzyme-linked immunosorbent assay for Antigen Detection |
NONE | CLIA kit for Platelet Derived Growth Factor Receptor Beta (PDGFRb) | CLIA assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | NONE | Recombinant Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Positive Control; Immunogen; SDS-PAGE; WB. |
NONE | Native Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Bioactivity | |
Antibodies | NONE | Monoclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | WB; IHC; ICC; IP. |
NONE | Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | WB; IHC; ICC; IF. | |
NONE | Biotin Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | ELISA(Det);IC; IH; IH(P); WB | |
NONE | APC Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | IHC, WB | |
NONE | HRP Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Simple Western; WB | |
NONE | PE Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Flow Cytometry | |
NONE | FITC Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Flow Cytometry;ICC/IF | |
Assay Kits | NONE | ELISA Kit for Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Enzyme-linked immunosorbent assay for Antigen Detection |
NONE | CLIA kit for Platelet Derived Growth Factor Receptor Beta (PDGFRb) | CLIA assay for Antigen Detection |
Organism species: Cavia (Guinea pig )
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | NONE | Recombinant Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Positive Control; Immunogen; SDS-PAGE; WB. |
NONE | Native Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Bioactivity | |
Antibodies | NONE | Monoclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | WB; IHC; ICC; IP. |
NONE | Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | WB; IHC; ICC; IF. | |
NONE | Biotin Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | ELISA(Det);IC; IH; IH(P); WB | |
NONE | APC Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | IHC, WB | |
NONE | HRP Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Simple Western; WB | |
NONE | PE Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Flow Cytometry | |
NONE | FITC Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Flow Cytometry;ICC/IF | |
Assay Kits | NONE | ELISA Kit for Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Enzyme-linked immunosorbent assay for Antigen Detection |
NONE | CLIA kit for Platelet Derived Growth Factor Receptor Beta (PDGFRb) | CLIA assay for Antigen Detection |
Organism species: Equus caballus; Equine (Horse)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | NONE | Recombinant Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Positive Control; Immunogen; SDS-PAGE; WB. |
NONE | Native Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Bioactivity | |
Antibodies | NONE | Monoclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | WB; IHC; ICC; IP. |
NONE | Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | WB; IHC; ICC; IF. | |
NONE | Biotin Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | ELISA(Det);IC; IH; IH(P); WB | |
NONE | APC Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | IHC, WB | |
NONE | HRP Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Simple Western; WB | |
NONE | PE Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Flow Cytometry | |
NONE | FITC Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Flow Cytometry;ICC/IF | |
Assay Kits | NONE | ELISA Kit for Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Enzyme-linked immunosorbent assay for Antigen Detection |
NONE | CLIA kit for Platelet Derived Growth Factor Receptor Beta (PDGFRb) | CLIA assay for Antigen Detection |
Organism species: Capra hircus; Caprine (Goat)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | NONE | Recombinant Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Positive Control; Immunogen; SDS-PAGE; WB. |
NONE | Native Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Bioactivity | |
Antibodies | NONE | Monoclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | WB; IHC; ICC; IP. |
NONE | Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | WB; IHC; ICC; IF. | |
NONE | Biotin Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | ELISA(Det);IC; IH; IH(P); WB | |
NONE | APC Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | IHC, WB | |
NONE | HRP Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Simple Western; WB | |
NONE | PE Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Flow Cytometry | |
NONE | FITC Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Flow Cytometry;ICC/IF | |
Assay Kits | NONE | ELISA Kit for Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Enzyme-linked immunosorbent assay for Antigen Detection |
NONE | CLIA kit for Platelet Derived Growth Factor Receptor Beta (PDGFRb) | CLIA assay for Antigen Detection |
Organism species: Pan-species (General)
PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
---|---|---|---|
Proteins | NONE | Recombinant Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Positive Control; Immunogen; SDS-PAGE; WB. |
NONE | Native Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Bioactivity | |
Antibodies | NONE | Monoclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | WB; IHC; ICC; IP. |
NONE | Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | WB; IHC; ICC; IF. | |
NONE | Biotin Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | ELISA(Det);IC; IH; IH(P); WB | |
NONE | APC Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | IHC, WB | |
NONE | HRP Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Simple Western; WB | |
NONE | PE Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Flow Cytometry | |
NONE | FITC Linked-Polyclonal Antibody to Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Flow Cytometry;ICC/IF | |
Assay Kits | NONE | ELISA Kit for Platelet Derived Growth Factor Receptor Beta (PDGFRb) | Enzyme-linked immunosorbent assay for Antigen Detection |
NONE | CLIA kit for Platelet Derived Growth Factor Receptor Beta (PDGFRb) | CLIA assay for Antigen Detection |
Reference
"Cloning and expression of a cDNA coding for the human platelet-derived growth factor receptor: evidence for more than one receptor class."
Proc. Natl. Acad. Sci. U.S.A. 85:3435-3439(1988) [PubMed] [Europe PMC] [Abstract]
"cDNA cloning and expression of a human platelet-derived growth factor (PDGF) receptor specific for B-chain-containing PDGF molecules."
Mol. Cell. Biol. 8:3476-3486(1988) [PubMed] [Europe PMC] [Abstract]
"Novel splice variants derived from the receptor tyrosine kinase superfamily are potential therapeutics for rheumatoid arthritis."
Arthritis Res. Ther. 10:R73-R73(2008) [PubMed] [Europe PMC] [Abstract]
"The DNA sequence and comparative analysis of human chromosome 5."
Nature 431:268-274(2004) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Integration of proviral DNA into the PDGF beta-receptor gene in HTLV-I-infected T-cells results in a novel tyrosine kinase product with transforming activity."
Oncogene 15:1051-1057(1997) [PubMed] [Europe PMC] [Abstract]
"Systematic screen for tyrosine kinase rearrangements identifies a novel C6orf204-PDGFRB fusion in a patient with recurrent T-ALL and an associated myeloproliferative neoplasm."
Genes Chromosomes Cancer 51:54-65(2012) [PubMed] [Europe PMC] [Abstract]
"Tandem linkage of human CSF-1 receptor (c-fms) and PDGF receptor genes."
Cell 55:655-661(1988) [PubMed] [Europe PMC] [Abstract]
"Signal peptide prediction based on analysis of experimentally verified cleavage sites."
Protein Sci. 13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]
"Autophosphorylation of the PDGF receptor in the kinase insert region regulates interactions with cell proteins."
Cell 58:1121-1133(1989) [PubMed] [Europe PMC] [Abstract]
"Independent expression of human alpha or beta platelet-derived growth factor receptor cDNAs in a naive hematopoietic cell leads to functional coupling with mitogenic and chemotactic signaling pathways."
Proc. Natl. Acad. Sci. U.S.A. 86:8314-8318(1989) [PubMed] [Europe PMC] [Abstract]
"Functions of the major tyrosine phosphorylation site of the PDGF receptor beta subunit."
Cell Regul. 2:413-425(1991) [PubMed] [Europe PMC] [Abstract]
"Platelet-derived growth factor (PDGF) stimulates PDGF receptor subunit dimerization and intersubunit trans-phosphorylation."
J. Biol. Chem. 266:8987-8992(1991) [PubMed] [Europe PMC] [Abstract]
"Effect of receptor kinase inactivation on the rate of internalization and degradation of PDGF and the PDGF beta-receptor."
J. Cell Biol. 112:469-478(1991) [PubMed] [Europe PMC] [Abstract]
"Phosphorylation sites in the PDGF receptor with different specificities for binding GAP and PI3 kinase in vivo."
EMBO J. 11:1373-1382(1992) [PubMed] [Europe PMC] [Abstract]
"Identification of two C-terminal autophosphorylation sites in the PDGF beta-receptor: involvement in the interaction with phospholipase C-gamma."
EMBO J. 11:3911-3919(1992) [PubMed] [Europe PMC] [Abstract]
"Ligand-induced polyubiquitination of the platelet-derived growth factor beta-receptor."
J. Biol. Chem. 267:6429-6434(1992) [PubMed] [Europe PMC] [Abstract]
"GTPase-activating protein and phosphatidylinositol 3-kinase bind to distinct regions of the platelet-derived growth factor receptor beta subunit."
Mol. Cell. Biol. 12:2534-2544(1992) [PubMed] [Europe PMC] [Abstract]
"Identification of two juxtamembrane autophosphorylation sites in the PDGF beta-receptor; involvement in the interaction with Src family tyrosine kinases."
EMBO J. 12:2257-2264(1993) [PubMed] [Europe PMC] [Abstract]
"Mechanism of platelet-derived growth factor (PDGF) AA, AB, and BB binding to alpha and beta PDGF receptor."
J. Biol. Chem. 268:3625-3631(1993) [PubMed] [Europe PMC] [Abstract]
"Activation of the SH2-containing phosphotyrosine phosphatase SH-PTP2 by its binding site, phosphotyrosine 1009, on the human platelet-derived growth factor receptor."
J. Biol. Chem. 268:21478-21481(1993) [PubMed] [Europe PMC] [Abstract]
"Two signaling molecules share a phosphotyrosine-containing binding site in the platelet-derived growth factor receptor."
Mol. Cell. Biol. 13:6889-6896(1993) [PubMed] [Europe PMC] [Abstract]
"Shb is a ubiquitously expressed Src homology 2 protein."
Oncogene 9:19-27(1994) [PubMed] [Europe PMC] [Abstract]
"Grb7 is a downstream signaling component of platelet-derived growth factor alpha- and beta-receptors."
J. Biol. Chem. 271:30942-30949(1996) [PubMed] [Europe PMC] [Abstract]
"Fusion of the platelet-derived growth factor receptor beta to a novel gene CEV14 in acute myelogenous leukemia after clonal evolution."
Blood 90:4271-4277(1997) [PubMed] [Europe PMC] [Abstract]
"Grb10, a positive, stimulatory signaling adapter in platelet-derived growth factor BB-, insulin-like growth factor I-, and insulin-mediated mitogenesis."
Mol. Cell. Biol. 19:6217-6228(1999) [PubMed] [Europe PMC] [Abstract]
"APS, an adaptor protein containing PH and SH2 domains, is associated with the PDGF receptor and c-Cbl and inhibits PDGF-induced mitogenesis."
Oncogene 18:759-767(1999) [PubMed] [Europe PMC] [Abstract]
"Site-selective dephosphorylation of the platelet-derived growth factor beta-receptor by the receptor-like protein-tyrosine phosphatase DEP-1."
J. Biol. Chem. 275:16219-16226(2000) [PubMed] [Europe PMC] [Abstract]
"Class II phosphoinositide 3-kinases are downstream targets of activated polypeptide growth factor receptors."
Mol. Cell. Biol. 20:3817-3830(2000) [PubMed] [Europe PMC] [Abstract]
"Platelet-derived growth factor C (PDGF-C), a novel growth factor that binds to PDGF alpha and beta receptor."
J. Biol. Chem. 276:27406-27414(2001) [PubMed] [Europe PMC] [Abstract]
"PDGF-D is a specific, protease-activated ligand for the PDGF beta-receptor."
Nat. Cell Biol. 3:512-516(2001) [PubMed] [Europe PMC] [Abstract]
"Response to imatinib mesylate in patients with chronic myeloproliferative diseases with rearrangements of the platelet-derived growth factor receptor beta."
N. Engl. J. Med. 347:481-487(2002) [PubMed] [Europe PMC] [Abstract]
"Cloning of the t(1;5)(q23;q33) in a myeloproliferative disorder associated with eosinophilia: involvement of PDGFRB and response to imatinib."
Blood 102:4187-4190(2003) [PubMed] [Europe PMC] [Abstract]
"HCMOGT-1 is a novel fusion partner to PDGFRB in juvenile myelomonocytic leukemia with t(5;17)(q33;p11.2)."
Cancer Res. 64:2649-2651(2004) [PubMed] [Europe PMC] [Abstract]
"p53-Binding protein 1 is fused to the platelet-derived growth factor receptor beta in a patient with a t(5;15)(q33;q22) and an imatinib-responsive eosinophilic myeloproliferative disorder."
Cancer Res. 64:7216-7219(2004) [PubMed] [Europe PMC] [Abstract]
"Site-selective regulation of platelet-derived growth factor beta receptor tyrosine phosphorylation by T-cell protein tyrosine phosphatase."
Mol. Cell. Biol. 24:2190-2201(2004) [PubMed] [Europe PMC] [Abstract]
"Regulation of PDGF signalling and vascular remodelling by peroxiredoxin II."
Nature 435:347-353(2005) [PubMed] [Europe PMC] [Abstract]
"Binding of Cbl to a phospholipase Cgamma1-docking site on platelet-derived growth factor receptor beta provides a dual mechanism of negative regulation."
J. Biol. Chem. 282:29336-29347(2007) [PubMed] [Europe PMC] [Abstract]
"A novel signaling axis of matriptase/PDGF-D/ss-PDGFR in human prostate cancer."
Cancer Res. 70:9631-9640(2010) [PubMed] [Europe PMC] [Abstract]
"Mutation of tyrosine residue 857 in the PDGF beta-receptor affects cell proliferation but not migration."
Cell. Signal. 22:1363-1368(2010) [PubMed] [Europe PMC] [Abstract]
"Stimulation of platelet-derived growth factor receptor beta (PDGFRbeta) activates ADAM17 and promotes metalloproteinase-dependent cross-talk between the PDGFRbeta and epidermal growth factor receptor (EGFR) signaling pathways."
J. Biol. Chem. 285:25024-25032(2010) [PubMed] [Europe PMC] [Abstract]
"Glyceollins inhibit platelet-derived growth factor-mediated human arterial smooth muscle cell proliferation and migration."
Br. J. Nutr. 107:24-35(2012) [PubMed] [Europe PMC] [Abstract]
"Direct interaction between Shc and the platelet-derived growth factor beta-receptor."
J. Biol. Chem. 269:15337-15343(1994) [PubMed] [Europe PMC] [Abstract]
"Disruption of platelet-derived growth factor-dependent phosphatidylinositol 3-kinase and phospholipase Cgamma 1 activity abolishes vascular smooth muscle cell proliferation and migration and attenuates neointima formation in vivo."
J. Am. Coll. Cardiol. 57:2527-2538(2011) [PubMed] [Europe PMC] [Abstract]
"Signal transduction via platelet-derived growth factor receptors."
Biochim. Biophys. Acta 1378:F79-113(1998) [PubMed] [Europe PMC] [Abstract]
"PDGF receptors-mediators of autocrine tumor growth and regulators of tumor vasculature and stroma."
Cytokine Growth Factor Rev. 15:275-286(2004) [PubMed] [Europe PMC] [Abstract]
"PDGF receptors as targets in tumor treatment."
Adv. Cancer Res. 97:247-274(2007) [PubMed] [Europe PMC] [Abstract]
"Role of platelet-derived growth factors in physiology and medicine."
Genes Dev. 22:1276-1312(2008) [PubMed] [Europe PMC] [Abstract]
"NMR trial models: experiences with the colicin immunity protein Im7 and the p85alpha C-terminal SH2-peptide complex."
Acta Crystallogr. D 57:1397-1404(2001) [PubMed] [Europe PMC] [Abstract]
"Structural determinants of the Na+/H+ exchanger regulatory factor interaction with the beta 2 adrenergic and platelet-derived growth factor receptors."
J. Biol. Chem. 277:18973-18978(2002) [PubMed] [Europe PMC] [Abstract]
"Structures of a platelet-derived growth factor/propeptide complex and a platelet-derived growth factor/receptor complex."
Proc. Natl. Acad. Sci. U.S.A. 107:11307-11312(2010) [PubMed] [Europe PMC] [Abstract]
"Patterns of somatic mutation in human cancer genomes."
Nature 446:153-158(2007) [PubMed] [Europe PMC] [Abstract]
"Mutations in PDGFRB cause autosomal-dominant infantile myofibromatosis."
Am. J. Hum. Genet. 92:1001-1007(2013) [PubMed] [Europe PMC] [Abstract]
"A recurrent PDGFRB mutation causes familial infantile myofibromatosis."
Am. J. Hum. Genet. 92:996-1000(2013) [PubMed] [Europe PMC] [Abstract]
"Mutation of the PDGFRB gene as a cause of idiopathic basal ganglia calcification."
Neurology 80:181-187(2013) [PubMed] [Europe PMC] [Abstract]