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Major Histocompatibility Complex Class I A (MHCA)

HLA-A; HLAA; MHC-A; Leukocyte Antigen A; HLA class I histocompatibility antigen, A-31 alpha chain

SPN U759
HGNC 4931
MGI 95904
PubMed 24244023
UniProt P16189
Wiki HLA-A
HLA-A is a component of certain MHC class I cell surface receptor isoforms that resides on the surface of all nucleated cells and platelets. The receptor is a heterodimer, and is composed of a heavy, α chain, and smaller beta (β) chain. The alpha chain is encoded by a variant HLA-A gene and the beta chain (β2-microglobulin) is composed by the invariant Beta-2 microglobulin gene.
For humans, as in most mammalian populations, MHC Class I molecules are extremely variable in their primary structure, and HLA-A is ranked among the genes in humans with the fastest evolving coding sequence. After typing millions of individuals, hundreds of variant alleles and isoforms have been identified.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins U759Hu01 Recombinant Major Histocompatibility Complex Class I A (MHCA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Major Histocompatibility Complex Class I A (MHCA) Bioactivity
Antibodies MU759Hu21 Monoclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) WB; IHC; ICC; IP.
PU759Hu01 Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) Flow Cytometry;ICC/IF
Assay Kits KEU759Hu ELISA Kit for Major Histocompatibility Complex Class I A (MHCA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Major Histocompatibility Complex Class I A (MHCA) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Major Histocompatibility Complex Class I A (MHCA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Major Histocompatibility Complex Class I A (MHCA) Bioactivity
Antibodies NONE Monoclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Major Histocompatibility Complex Class I A (MHCA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Major Histocompatibility Complex Class I A (MHCA) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Major Histocompatibility Complex Class I A (MHCA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Major Histocompatibility Complex Class I A (MHCA) Bioactivity
Antibodies NONE Monoclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Major Histocompatibility Complex Class I A (MHCA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Major Histocompatibility Complex Class I A (MHCA) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Major Histocompatibility Complex Class I A (MHCA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Major Histocompatibility Complex Class I A (MHCA) Bioactivity
Antibodies NONE Monoclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Major Histocompatibility Complex Class I A (MHCA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Major Histocompatibility Complex Class I A (MHCA) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Major Histocompatibility Complex Class I A (MHCA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Major Histocompatibility Complex Class I A (MHCA) Bioactivity
Antibodies NONE Monoclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Major Histocompatibility Complex Class I A (MHCA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Major Histocompatibility Complex Class I A (MHCA) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Major Histocompatibility Complex Class I A (MHCA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Major Histocompatibility Complex Class I A (MHCA) Bioactivity
Antibodies NONE Monoclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Major Histocompatibility Complex Class I A (MHCA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Major Histocompatibility Complex Class I A (MHCA) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Major Histocompatibility Complex Class I A (MHCA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Major Histocompatibility Complex Class I A (MHCA) Bioactivity
Antibodies NONE Monoclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Major Histocompatibility Complex Class I A (MHCA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Major Histocompatibility Complex Class I A (MHCA) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Major Histocompatibility Complex Class I A (MHCA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Major Histocompatibility Complex Class I A (MHCA) Bioactivity
Antibodies NONE Monoclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Major Histocompatibility Complex Class I A (MHCA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Major Histocompatibility Complex Class I A (MHCA) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Major Histocompatibility Complex Class I A (MHCA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Major Histocompatibility Complex Class I A (MHCA) Bioactivity
Antibodies NONE Monoclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Major Histocompatibility Complex Class I A (MHCA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Major Histocompatibility Complex Class I A (MHCA) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Major Histocompatibility Complex Class I A (MHCA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Major Histocompatibility Complex Class I A (MHCA) Bioactivity
Antibodies NONE Monoclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) WB; IHC; ICC; IP.
PU759Rb51 Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Major Histocompatibility Complex Class I A (MHCA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Major Histocompatibility Complex Class I A (MHCA) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Major Histocompatibility Complex Class I A (MHCA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Major Histocompatibility Complex Class I A (MHCA) Bioactivity
Antibodies NONE Monoclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Major Histocompatibility Complex Class I A (MHCA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Major Histocompatibility Complex Class I A (MHCA) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Major Histocompatibility Complex Class I A (MHCA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Major Histocompatibility Complex Class I A (MHCA) Bioactivity
Antibodies NONE Monoclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Major Histocompatibility Complex Class I A (MHCA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Major Histocompatibility Complex Class I A (MHCA) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Major Histocompatibility Complex Class I A (MHCA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Major Histocompatibility Complex Class I A (MHCA) Bioactivity
Antibodies NONE Monoclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Major Histocompatibility Complex Class I A (MHCA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Major Histocompatibility Complex Class I A (MHCA) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Major Histocompatibility Complex Class I A (MHCA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Major Histocompatibility Complex Class I A (MHCA) Bioactivity
Antibodies NONE Monoclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Major Histocompatibility Complex Class I A (MHCA) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Major Histocompatibility Complex Class I A (MHCA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Major Histocompatibility Complex Class I A (MHCA) CLIA assay for Antigen Detection

Reference

"Molecular analysis of the serologically defined HLA-Aw19 antigens. A genetically distinct family of HLA-A antigens comprising A29, A31, A32, and Aw33, but probably not A30."
J. Immunol. 143:3371-3378(1989) [PubMed] [Europe PMC] [Abstract]

"Unusual HLA-B alleles in two tribes of Brazilian Indians."
Nature 357:326-329(1992) [PubMed] [Europe PMC] [Abstract]

"On the sequence of A*3101."
Tissue Antigens 47:428-430(1996) [PubMed] [Europe PMC] [Abstract]

"New recombinant HLA-B alleles in a tribe of South American Amerindians indicate rapid evolution of MHC class I loci."
Nature 357:329-333(1992) [PubMed] [Europe PMC] [Abstract]

"Non-conservative substitutions distinguish previously uncharacterized HLA-A molecules."
Tissue Antigens 57:95-102(2001) [PubMed] [Europe PMC] [Abstract]

"Initial characterization of the human central proteome."
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

"HLA-A*3101 and carbamazepine-induced hypersensitivity reactions in Europeans."
N. Engl. J. Med. 364:1134-1143(2011) [PubMed] [Europe PMC] [Abstract]

"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]

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