Integrin Beta 5 (ITGb5)
ITG-B5
Integrin, beta 5 has been shown to interact with PTK2,Annexin A5and PAK4.McLean et al. isolated cDNA clones coding for the beta-5 subunit of the novel integrin receptor involved in cell adhesion to the matrix protein vitronectin which had been found in a human lung epithelial-derived cell line. This receptor had an alpha subunit that appeared to be identical to that in another vitronectin receptor, but the beta subunit was distinctive. McLean et al. demonstrated that the 3.3-kb mRNA coded for a mature protein of 775 amino acid residues with a hydrophobic leader sequence of 24 amino acids. A 56% identity was found between the beta-5 and beta-3 protein sequences, making them the most closely related of the integrin beta subunits.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU746Hu01 | Recombinant Integrin Beta 5 (ITGb5) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU746Hu01 | Monoclonal Antibody to Integrin Beta 5 (ITGb5) | WB; IHC; ICC; IP. |
| PAU746Hu01 | Polyclonal Antibody to Integrin Beta 5 (ITGb5) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU746Hu01 | CLIA Kit for Integrin Beta 5 (ITGb5) | CLIA assay for Antigen Detection |
| ELU746Hu01 | ELISA Kit for Integrin Beta 5 (ITGb5) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU746Mu01 | Recombinant Integrin Beta 5 (ITGb5) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU746Mu01 | Monoclonal Antibody to Integrin Beta 5 (ITGb5) | WB; IHC; ICC; IP. |
| PAU746Mu01 | Polyclonal Antibody to Integrin Beta 5 (ITGb5) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU746Mu01 | CLIA Kit for Integrin Beta 5 (ITGb5) | CLIA assay for Antigen Detection |
| ELU746Mu01 | ELISA Kit for Integrin Beta 5 (ITGb5) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU746Ra01 | Recombinant Integrin Beta 5 (ITGb5) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU746Ra01 | Monoclonal Antibody to Integrin Beta 5 (ITGb5) | WB; IHC; ICC; IP. |
| PAU746Ra01 | Polyclonal Antibody to Integrin Beta 5 (ITGb5) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU746Ra01 | CLIA Kit for Integrin Beta 5 (ITGb5) | CLIA assay for Antigen Detection |
| ELU746Ra01 | ELISA Kit for Integrin Beta 5 (ITGb5) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU746Ca01 | Recombinant Integrin Beta 5 (ITGb5) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU746Ca01 | Monoclonal Antibody to Integrin Beta 5 (ITGb5) | WB; IHC; ICC; IP. |
| PAU746Ca01 | Polyclonal Antibody to Integrin Beta 5 (ITGb5) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU746Ca01 | CLIA Kit for Integrin Beta 5 (ITGb5) | CLIA assay for Antigen Detection |
| ELU746Ca01 | ELISA Kit for Integrin Beta 5 (ITGb5) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU746Po01 | Recombinant Integrin Beta 5 (ITGb5) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU746Po01 | Monoclonal Antibody to Integrin Beta 5 (ITGb5) | WB; IHC; ICC; IP. |
| PAU746Po01 | Polyclonal Antibody to Integrin Beta 5 (ITGb5) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU746Po01 | CLIA Kit for Integrin Beta 5 (ITGb5) | CLIA assay for Antigen Detection |
| ELU746Po01 | ELISA Kit for Integrin Beta 5 (ITGb5) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU746Bo01 | Recombinant Integrin Beta 5 (ITGb5) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU746Bo01 | Monoclonal Antibody to Integrin Beta 5 (ITGb5) | WB; IHC; ICC; IP. |
| PAU746Bo01 | Polyclonal Antibody to Integrin Beta 5 (ITGb5) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU746Bo01 | CLIA Kit for Integrin Beta 5 (ITGb5) | CLIA assay for Antigen Detection |
| ELU746Bo01 | ELISA Kit for Integrin Beta 5 (ITGb5) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU746Rb01 | Recombinant Integrin Beta 5 (ITGb5) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU746Rb01 | Monoclonal Antibody to Integrin Beta 5 (ITGb5) | WB; IHC; ICC; IP. |
| PAU746Rb01 | Polyclonal Antibody to Integrin Beta 5 (ITGb5) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU746Rb01 | CLIA Kit for Integrin Beta 5 (ITGb5) | CLIA assay for Antigen Detection |
| ELU746Rb01 | ELISA Kit for Integrin Beta 5 (ITGb5) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU746Mo01 | Recombinant Integrin Beta 5 (ITGb5) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU746Mo01 | Monoclonal Antibody to Integrin Beta 5 (ITGb5) | WB; IHC; ICC; IP. |
| PAU746Mo01 | Polyclonal Antibody to Integrin Beta 5 (ITGb5) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU746Mo01 | CLIA Kit for Integrin Beta 5 (ITGb5) | CLIA assay for Antigen Detection |
| ELU746Mo01 | ELISA Kit for Integrin Beta 5 (ITGb5) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Cloning, primary structure and properties of a novel human integrin beta subunit."
EMBO J. 9:1561-1568(1990) [PubMed] [Europe PMC] [Abstract]
"Cloning of an integrin beta subunit exhibiting high homology with integrin beta 3 subunit."
Proc. Natl. Acad. Sci. U.S.A. 87:5354-5358(1990) [PubMed] [Europe PMC] [Abstract]
"cDNA sequence of the human integrin beta 5 subunit."
J. Biol. Chem. 265:17126-17131(1990) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Myosin-X provides a motor-based link between integrins and the cytoskeleton."
Nat. Cell Biol. 6:523-531(2004) [PubMed] [Europe PMC] [Abstract]
"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]