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Growth Differentiation Factor 3 (GDF3)

Vgr2; Vg-Related Gene 2

SPN U735
HGNC 4218
MGI 95686
PubMed 21805089
RGD 1564178
UniProt Q9NR23
Wiki GDF3

Growth differentiation factor-3 (GDF3) is protein belonging to the transforming growth factor beta (TGF-beta) superfamily. It has high similarity to other TGF-beta; superfamily members called Vg1 (found in frogs), BMP2, BMP6 and GDF1, but lacks one of the conserved cysteine residues common to all other TGF-beta; superfamily members.Expression of GDF3 occurs in ossifying bone during embryonic development and in the brain, thymus, spleen, bone marrow and adipose tissue of adults.
GDF3 is a bi-functional protein that inhibits some TGF-beta; superfamily members (e.g. BMPs) while activating others, thus regulating the balance between different modes of TGF-beta signaling. It has been shown to negatively and positively control differentiation of embryonic stem cells in mice and humans.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins U735Hu01 Recombinant Growth Differentiation Factor 3 (GDF3) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Growth Differentiation Factor 3 (GDF3) Bioactivity
Antibodies MU735Hu21 Monoclonal Antibody to Growth Differentiation Factor 3 (GDF3) WB; IHC; ICC; IP.
PU735Hu01 Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) WB; IHC; ICC; IF.
LU735Hu71 Biotin Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) Flow Cytometry;ICC/IF
Assay Kits KEU735Hu ELISA Kit for Growth Differentiation Factor 3 (GDF3) Enzyme-linked immunosorbent assay for Antigen Detection
KCU735Hu CLIA kit for Growth Differentiation Factor 3 (GDF3) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins U735Mu01 Recombinant Growth Differentiation Factor 3 (GDF3) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Growth Differentiation Factor 3 (GDF3) Bioactivity
Antibodies NONE Monoclonal Antibody to Growth Differentiation Factor 3 (GDF3) WB; IHC; ICC; IP.
PU735Mu01 Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) Flow Cytometry;ICC/IF
Assay Kits KEU735Mu ELISA Kit for Growth Differentiation Factor 3 (GDF3) Enzyme-linked immunosorbent assay for Antigen Detection
KCU735Mu CLIA kit for Growth Differentiation Factor 3 (GDF3) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins U735Ra01 Recombinant Growth Differentiation Factor 3 (GDF3) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Growth Differentiation Factor 3 (GDF3) Bioactivity
Antibodies MU735Ra21 Monoclonal Antibody to Growth Differentiation Factor 3 (GDF3) WB; IHC; ICC; IP.
PU735Ra01 Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) Flow Cytometry;ICC/IF
Assay Kits KEU735Ra ELISA Kit for Growth Differentiation Factor 3 (GDF3) Enzyme-linked immunosorbent assay for Antigen Detection
KCU735Ra CLIA kit for Growth Differentiation Factor 3 (GDF3) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Growth Differentiation Factor 3 (GDF3) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Growth Differentiation Factor 3 (GDF3) Bioactivity
Antibodies NONE Monoclonal Antibody to Growth Differentiation Factor 3 (GDF3) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Growth Differentiation Factor 3 (GDF3) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Growth Differentiation Factor 3 (GDF3) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Growth Differentiation Factor 3 (GDF3) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Growth Differentiation Factor 3 (GDF3) Bioactivity
Antibodies NONE Monoclonal Antibody to Growth Differentiation Factor 3 (GDF3) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Growth Differentiation Factor 3 (GDF3) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Growth Differentiation Factor 3 (GDF3) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Growth Differentiation Factor 3 (GDF3) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Growth Differentiation Factor 3 (GDF3) Bioactivity
Antibodies NONE Monoclonal Antibody to Growth Differentiation Factor 3 (GDF3) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Growth Differentiation Factor 3 (GDF3) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Growth Differentiation Factor 3 (GDF3) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Growth Differentiation Factor 3 (GDF3) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Growth Differentiation Factor 3 (GDF3) Bioactivity
Antibodies NONE Monoclonal Antibody to Growth Differentiation Factor 3 (GDF3) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Growth Differentiation Factor 3 (GDF3) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Growth Differentiation Factor 3 (GDF3) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Growth Differentiation Factor 3 (GDF3) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Growth Differentiation Factor 3 (GDF3) Bioactivity
Antibodies NONE Monoclonal Antibody to Growth Differentiation Factor 3 (GDF3) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Growth Differentiation Factor 3 (GDF3) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Growth Differentiation Factor 3 (GDF3) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Growth Differentiation Factor 3 (GDF3) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Growth Differentiation Factor 3 (GDF3) Bioactivity
Antibodies NONE Monoclonal Antibody to Growth Differentiation Factor 3 (GDF3) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Growth Differentiation Factor 3 (GDF3) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Growth Differentiation Factor 3 (GDF3) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Growth Differentiation Factor 3 (GDF3) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Growth Differentiation Factor 3 (GDF3) Bioactivity
Antibodies NONE Monoclonal Antibody to Growth Differentiation Factor 3 (GDF3) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Growth Differentiation Factor 3 (GDF3) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Growth Differentiation Factor 3 (GDF3) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Growth Differentiation Factor 3 (GDF3) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Growth Differentiation Factor 3 (GDF3) Bioactivity
Antibodies NONE Monoclonal Antibody to Growth Differentiation Factor 3 (GDF3) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Growth Differentiation Factor 3 (GDF3) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Growth Differentiation Factor 3 (GDF3) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Growth Differentiation Factor 3 (GDF3) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Growth Differentiation Factor 3 (GDF3) Bioactivity
Antibodies NONE Monoclonal Antibody to Growth Differentiation Factor 3 (GDF3) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Growth Differentiation Factor 3 (GDF3) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Growth Differentiation Factor 3 (GDF3) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Growth Differentiation Factor 3 (GDF3) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Growth Differentiation Factor 3 (GDF3) Bioactivity
Antibodies NONE Monoclonal Antibody to Growth Differentiation Factor 3 (GDF3) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Growth Differentiation Factor 3 (GDF3) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Growth Differentiation Factor 3 (GDF3) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Growth Differentiation Factor 3 (GDF3) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Growth Differentiation Factor 3 (GDF3) Bioactivity
Antibodies NONE Monoclonal Antibody to Growth Differentiation Factor 3 (GDF3) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Growth Differentiation Factor 3 (GDF3) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Growth Differentiation Factor 3 (GDF3) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Growth Differentiation Factor 3 (GDF3) CLIA assay for Antigen Detection

Reference

"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Mutation of the bone morphogenetic protein GDF3 causes ocular and skeletal anomalies."
Hum. Mol. Genet. 19:287-298(2010) [PubMed] [Europe PMC] [Abstract]

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