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Mothers Against Decapentaplegic Homolog 6 (Smad6)

MADH6; MADH7

SMAD family member 6, also known as SMAD6 is a protein that, as its name describes, is a homolog of the Drosophila gene "mothers against decapentaplegic". It belongs to the SMAD family of proteins, which belong to the TGF beta superfamily of modulators.

Like many other TGF beta family members SMAD6 is involved in cell signalling. It acts as a regulator of TGF beta family (such as bone morphogenetic proteins) activity by competing with SMAD4 and preventing the transcription of SMAD4's gene products. There are two known isoforms of this protein.The SMAD proteins are homologs of both the drosophila protein, mothers against decapentaplegic (MAD) and the C. elegans protein SMA. The name is a combination of the two.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins U724Hu01 Recombinant Mothers Against Decapentaplegic Homolog 6 (Smad6) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Mothers Against Decapentaplegic Homolog 6 (Smad6) Bioactivity
Antibodies NONE Monoclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) WB; IHC; ICC; IP.
PU724Hu01 Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Mothers Against Decapentaplegic Homolog 6 (Smad6) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Mothers Against Decapentaplegic Homolog 6 (Smad6) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins U724Mu01 Recombinant Mothers Against Decapentaplegic Homolog 6 (Smad6) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Mothers Against Decapentaplegic Homolog 6 (Smad6) Bioactivity
Antibodies NONE Monoclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) WB; IHC; ICC; IP.
PU724Mu01 Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Mothers Against Decapentaplegic Homolog 6 (Smad6) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Mothers Against Decapentaplegic Homolog 6 (Smad6) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins U724Ra01 Recombinant Mothers Against Decapentaplegic Homolog 6 (Smad6) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Mothers Against Decapentaplegic Homolog 6 (Smad6) Bioactivity
Antibodies NONE Monoclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) WB; IHC; ICC; IP.
PU724Ra01 Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Mothers Against Decapentaplegic Homolog 6 (Smad6) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Mothers Against Decapentaplegic Homolog 6 (Smad6) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Mothers Against Decapentaplegic Homolog 6 (Smad6) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Mothers Against Decapentaplegic Homolog 6 (Smad6) Bioactivity
Antibodies NONE Monoclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Mothers Against Decapentaplegic Homolog 6 (Smad6) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Mothers Against Decapentaplegic Homolog 6 (Smad6) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Mothers Against Decapentaplegic Homolog 6 (Smad6) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Mothers Against Decapentaplegic Homolog 6 (Smad6) Bioactivity
Antibodies NONE Monoclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Mothers Against Decapentaplegic Homolog 6 (Smad6) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Mothers Against Decapentaplegic Homolog 6 (Smad6) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Mothers Against Decapentaplegic Homolog 6 (Smad6) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Mothers Against Decapentaplegic Homolog 6 (Smad6) Bioactivity
Antibodies NONE Monoclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Mothers Against Decapentaplegic Homolog 6 (Smad6) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Mothers Against Decapentaplegic Homolog 6 (Smad6) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Mothers Against Decapentaplegic Homolog 6 (Smad6) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Mothers Against Decapentaplegic Homolog 6 (Smad6) Bioactivity
Antibodies NONE Monoclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Mothers Against Decapentaplegic Homolog 6 (Smad6) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Mothers Against Decapentaplegic Homolog 6 (Smad6) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Mothers Against Decapentaplegic Homolog 6 (Smad6) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Mothers Against Decapentaplegic Homolog 6 (Smad6) Bioactivity
Antibodies NONE Monoclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Mothers Against Decapentaplegic Homolog 6 (Smad6) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Mothers Against Decapentaplegic Homolog 6 (Smad6) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Mothers Against Decapentaplegic Homolog 6 (Smad6) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Mothers Against Decapentaplegic Homolog 6 (Smad6) Bioactivity
Antibodies NONE Monoclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Mothers Against Decapentaplegic Homolog 6 (Smad6) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Mothers Against Decapentaplegic Homolog 6 (Smad6) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Mothers Against Decapentaplegic Homolog 6 (Smad6) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Mothers Against Decapentaplegic Homolog 6 (Smad6) Bioactivity
Antibodies NONE Monoclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Mothers Against Decapentaplegic Homolog 6 (Smad6) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Mothers Against Decapentaplegic Homolog 6 (Smad6) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Mothers Against Decapentaplegic Homolog 6 (Smad6) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Mothers Against Decapentaplegic Homolog 6 (Smad6) Bioactivity
Antibodies NONE Monoclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Mothers Against Decapentaplegic Homolog 6 (Smad6) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Mothers Against Decapentaplegic Homolog 6 (Smad6) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Mothers Against Decapentaplegic Homolog 6 (Smad6) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Mothers Against Decapentaplegic Homolog 6 (Smad6) Bioactivity
Antibodies NONE Monoclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Mothers Against Decapentaplegic Homolog 6 (Smad6) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Mothers Against Decapentaplegic Homolog 6 (Smad6) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Mothers Against Decapentaplegic Homolog 6 (Smad6) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Mothers Against Decapentaplegic Homolog 6 (Smad6) Bioactivity
Antibodies NONE Monoclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Mothers Against Decapentaplegic Homolog 6 (Smad6) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Mothers Against Decapentaplegic Homolog 6 (Smad6) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Mothers Against Decapentaplegic Homolog 6 (Smad6) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Mothers Against Decapentaplegic Homolog 6 (Smad6) Bioactivity
Antibodies NONE Monoclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 6 (Smad6) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Mothers Against Decapentaplegic Homolog 6 (Smad6) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Mothers Against Decapentaplegic Homolog 6 (Smad6) CLIA assay for Antigen Detection

Reference

"Mad-related genes in the human."
Nat. Genet. 13:347-349(1996) [PubMed] [Europe PMC] [Abstract]

"Smad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor suppressor."
Genes Dev. 12:186-197(1998) [PubMed] [Europe PMC] [Abstract]

"Induction of inhibitory Smad6 and Smad7 mRNA by TGF-beta family members."
Biochem. Biophys. Res. Commun. 249:505-511(1998) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"TGF-beta signal transduction."
Annu. Rev. Biochem. 67:753-791(1998) [PubMed] [Europe PMC] [Abstract]

"Remarkable versatility of Smad proteins in the nucleus of transforming growth factor-beta activated cells."
Cytokine Growth Factor Rev. 10:187-199(1999) [PubMed] [Europe PMC] [Abstract]

"The Smad pathway."
Cytokine Growth Factor Rev. 11:5-13(2000) [PubMed] [Europe PMC] [Abstract]

"TGF-beta signaling by Smad proteins."
Cytokine Growth Factor Rev. 11:15-22(2000) [PubMed] [Europe PMC] [Abstract]

"Smad6 as a transcriptional corepressor."
J. Biol. Chem. 275:8267-8270(2000) [PubMed] [Europe PMC] [Abstract]

"Human truncated Smad 6 (Smad 6s) inhibits the BMP pathway in Xenopus laevis."
Dev. Growth Differ. 43:115-132(2001) [PubMed] [Europe PMC] [Abstract]

"Promoting bone morphogenetic protein signaling through negative regulation of inhibitory Smads."
EMBO J. 20:4132-4142(2001) [PubMed] [Europe PMC] [Abstract]

"Arkadia amplifies TGF-beta superfamily signaling through degradation of Smad7."
EMBO J. 22:6458-6470(2003) [PubMed] [Europe PMC] [Abstract]

"Axin is a scaffold protein in TGF-beta signaling that promotes degradation of Smad7 by Arkadia."
EMBO J. 25:1646-1658(2006) [PubMed] [Europe PMC] [Abstract]

"Smad6 negatively regulates interleukin 1-receptor-Toll-like receptor signaling through direct interaction with the adaptor Pellino-1."
Nat. Immunol. 7:1057-1065(2006) [PubMed] [Europe PMC] [Abstract]

"Smad6 is a protein kinase X phosphorylation substrate and is required for HL-60 cell differentiation."
Oncogene 25:4086-4098(2006) [PubMed] [Europe PMC] [Abstract]

"Nonsynonymous variants in the SMAD6 gene predispose to congenital cardiovascular malformation."
Hum. Mutat. 33:720-727(2012) [PubMed] [Europe PMC] [Abstract]

"Fine-tuning BMP7 signalling in adipogenesis by UBE2O/E2-230K-mediated monoubiquitination of SMAD6."
EMBO J. 32:996-1007(2013) [PubMed] [Europe PMC] [Abstract]