Mothers Against Decapentaplegic Homolog 3 (Smad3)
JV15-2; MADH3
SMAD3 or Mothers against decapentaplegic homolog 3 is a gene which appears in humans on chromosome 15. It is one of several human homologues of a gene which was originally discovered in the fruit fly Drosophila melanogaster. The name SMAD3 also refers to a member of the SMAD family of proteins.
SMAD3 or Mothers against decapentaplegic homolog 3 is a polypeptide that, as its name describes, is a homolog of the Drosophila protein "Mothers against decapentaplegic". It belongs to the SMAD family of proteins, which belong to the TGF beta superfamily of modulators. Like many other TGF beta family members, SMAD3 is involved in cell signalling. SMAD3 modulates signals of activin and TGF beta;'s.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | U721Hu01 | Recombinant Mothers Against Decapentaplegic Homolog 3 (Smad3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Mothers Against Decapentaplegic Homolog 3 (Smad3) | Bioactivity | |
| Antibodies | MU721Hu22 | Monoclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | WB; IHC; ICC; IP. |
| PU721Hu01 | Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Mothers Against Decapentaplegic Homolog 3 (Smad3) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Mothers Against Decapentaplegic Homolog 3 (Smad3) | CLIA assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | U721Mu02 | Recombinant Mothers Against Decapentaplegic Homolog 3 (Smad3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Mothers Against Decapentaplegic Homolog 3 (Smad3) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | WB; IHC; ICC; IP. |
| PU721Mu01 | Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | WB; IHC; ICC; IF. | |
| LU721Mu71 | Biotin Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Mothers Against Decapentaplegic Homolog 3 (Smad3) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Mothers Against Decapentaplegic Homolog 3 (Smad3) | CLIA assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | U721Ra01 | Recombinant Mothers Against Decapentaplegic Homolog 3 (Smad3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Mothers Against Decapentaplegic Homolog 3 (Smad3) | Bioactivity | |
| Antibodies | MU721Ra21 | Monoclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | WB; IHC; ICC; IP. |
| PU721Ra01 | Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Mothers Against Decapentaplegic Homolog 3 (Smad3) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Mothers Against Decapentaplegic Homolog 3 (Smad3) | CLIA assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Mothers Against Decapentaplegic Homolog 3 (Smad3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Mothers Against Decapentaplegic Homolog 3 (Smad3) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Mothers Against Decapentaplegic Homolog 3 (Smad3) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Mothers Against Decapentaplegic Homolog 3 (Smad3) | CLIA assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Mothers Against Decapentaplegic Homolog 3 (Smad3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Mothers Against Decapentaplegic Homolog 3 (Smad3) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Mothers Against Decapentaplegic Homolog 3 (Smad3) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Mothers Against Decapentaplegic Homolog 3 (Smad3) | CLIA assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Mothers Against Decapentaplegic Homolog 3 (Smad3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Mothers Against Decapentaplegic Homolog 3 (Smad3) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Mothers Against Decapentaplegic Homolog 3 (Smad3) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Mothers Against Decapentaplegic Homolog 3 (Smad3) | CLIA assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Mothers Against Decapentaplegic Homolog 3 (Smad3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Mothers Against Decapentaplegic Homolog 3 (Smad3) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Mothers Against Decapentaplegic Homolog 3 (Smad3) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Mothers Against Decapentaplegic Homolog 3 (Smad3) | CLIA assay for Antigen Detection |
Organism species: Chicken (Gallus)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Mothers Against Decapentaplegic Homolog 3 (Smad3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Mothers Against Decapentaplegic Homolog 3 (Smad3) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Mothers Against Decapentaplegic Homolog 3 (Smad3) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Mothers Against Decapentaplegic Homolog 3 (Smad3) | CLIA assay for Antigen Detection |
Organism species: Ovis aries; Ovine (Sheep)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Mothers Against Decapentaplegic Homolog 3 (Smad3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Mothers Against Decapentaplegic Homolog 3 (Smad3) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Mothers Against Decapentaplegic Homolog 3 (Smad3) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Mothers Against Decapentaplegic Homolog 3 (Smad3) | CLIA assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Mothers Against Decapentaplegic Homolog 3 (Smad3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Mothers Against Decapentaplegic Homolog 3 (Smad3) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | Flow Cytometry;ICC/IF | |
| Assay Kits | KEU721Rb | ELISA Kit for Mothers Against Decapentaplegic Homolog 3 (Smad3) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Mothers Against Decapentaplegic Homolog 3 (Smad3) | CLIA assay for Antigen Detection |
Organism species: Cavia (Guinea pig )
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Mothers Against Decapentaplegic Homolog 3 (Smad3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Mothers Against Decapentaplegic Homolog 3 (Smad3) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Mothers Against Decapentaplegic Homolog 3 (Smad3) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Mothers Against Decapentaplegic Homolog 3 (Smad3) | CLIA assay for Antigen Detection |
Organism species: Equus caballus; Equine (Horse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Mothers Against Decapentaplegic Homolog 3 (Smad3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Mothers Against Decapentaplegic Homolog 3 (Smad3) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Mothers Against Decapentaplegic Homolog 3 (Smad3) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Mothers Against Decapentaplegic Homolog 3 (Smad3) | CLIA assay for Antigen Detection |
Organism species: Capra hircus; Caprine (Goat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Mothers Against Decapentaplegic Homolog 3 (Smad3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Mothers Against Decapentaplegic Homolog 3 (Smad3) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Mothers Against Decapentaplegic Homolog 3 (Smad3) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Mothers Against Decapentaplegic Homolog 3 (Smad3) | CLIA assay for Antigen Detection |
Organism species: Pan-species (General)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Mothers Against Decapentaplegic Homolog 3 (Smad3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Mothers Against Decapentaplegic Homolog 3 (Smad3) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Mothers Against Decapentaplegic Homolog 3 (Smad3) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Mothers Against Decapentaplegic Homolog 3 (Smad3) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Mothers Against Decapentaplegic Homolog 3 (Smad3) | CLIA assay for Antigen Detection |
Reference
"Receptor-associated Mad homologues synergize as effectors of the TGF-beta response."
Nature 383:168-172(1996) [PubMed] [Europe PMC] [Abstract]
"Mad-related genes in the human."
Nat. Genet. 13:347-349(1996) [PubMed] [Europe PMC] [Abstract]
"Genomic structure of the human Smad3 gene and its infrequent alterations in colorectal cancers."
Cancer Lett. 122:157-163(1998) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"Analysis of the DNA sequence and duplication history of human chromosome 15."
Nature 440:671-675(2006) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4."
EMBO J. 16:5353-5362(1997) [PubMed] [Europe PMC] [Abstract]
"SARA, a FYVE domain protein that recruits Smad2 to the TGFbeta receptor."
Cell 95:779-791(1998) [PubMed] [Europe PMC] [Abstract]
"Smad proteins exist as monomers in vivo and undergo homo- and hetero-oligomerization upon activation by serine/threonine kinase receptors."
EMBO J. 17:4056-4065(1998) [PubMed] [Europe PMC] [Abstract]
"TGF-beta-induced phosphorylation of Smad3 regulates its interaction with coactivator p300/CREB-binding protein."
Mol. Biol. Cell 9:3309-3319(1998) [PubMed] [Europe PMC] [Abstract]
"The oncoprotein Evi-1 represses TGF-beta signalling by inhibiting Smad3."
Nature 394:92-96(1998) [PubMed] [Europe PMC] [Abstract]
"Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-beta-induced transcription."
Nature 394:909-913(1998) [PubMed] [Europe PMC] [Abstract]
"Roles of pathway-specific and inhibitory Smads in activin receptor signaling."
Mol. Endocrinol. 13:15-23(1999) [PubMed] [Europe PMC] [Abstract]
"Structural and functional characterization of the transforming growth factor-beta -induced Smad3/c-Jun transcriptional cooperativity."
J. Biol. Chem. 275:38802-38812(2000) [PubMed] [Europe PMC] [Abstract]
"The adaptor molecule Disabled-2 links the transforming growth factor beta receptors to the Smad pathway."
EMBO J. 20:2789-2801(2001) [PubMed] [Europe PMC] [Abstract]
"Ski-interacting protein interacts with Smad proteins to augment transforming growth factor-beta-dependent transcription."
J. Biol. Chem. 276:18243-18248(2001) [PubMed] [Europe PMC] [Abstract]
"TGIF2 interacts with histone deacetylase 1 and represses transcription."
J. Biol. Chem. 276:32109-32114(2001) [PubMed] [Europe PMC] [Abstract]
"The L3 loop and C-terminal phosphorylation jointly define Smad protein trimerization."
Nat. Struct. Biol. 8:248-253(2001) [PubMed] [Europe PMC] [Abstract]
"Inactivation of menin, a Smad3-interacting protein, blocks transforming growth factor type beta signaling."
Proc. Natl. Acad. Sci. U.S.A. 98:3837-3842(2001) [PubMed] [Europe PMC] [Abstract]
"DACH1 inhibits transforming growth factor-beta signaling through binding Smad4."
J. Biol. Chem. 278:51673-51684(2003) [PubMed] [Europe PMC] [Abstract]
"Cyclin-dependent kinases regulate the antiproliferative function of Smads."
Nature 430:226-231(2004) [PubMed] [Europe PMC] [Abstract]
"The Smad3 linker region contains a transcriptional activation domain."
Biochem. J. 386:29-34(2005) [PubMed] [Europe PMC] [Abstract]
"Identification and characterization of ERK MAP kinase phosphorylation sites in Smad3."
Biochemistry 44:12546-12553(2005) [PubMed] [Europe PMC] [Abstract]
"MAN1, an integral protein of the inner nuclear membrane, binds Smad2 and Smad3 and antagonizes transforming growth factor-beta signaling."
Hum. Mol. Genet. 14:437-445(2005) [PubMed] [Europe PMC] [Abstract]
"Novel function of androgen receptor-associated protein 55/Hic-5 as a negative regulator of Smad3 signaling."
J. Biol. Chem. 280:5154-5162(2005) [PubMed] [Europe PMC] [Abstract]
"The integral inner nuclear membrane protein MAN1 physically interacts with the R-Smad proteins to repress signaling by the transforming growth factor-{beta} superfamily of cytokines."
J. Biol. Chem. 280:15992-16001(2005) [PubMed] [Europe PMC] [Abstract]
"Nuclear targeting of transforming growth factor-beta-activated Smad complexes."
J. Biol. Chem. 280:21329-21336(2005) [PubMed] [Europe PMC] [Abstract]
"Cloning and functional characterization of a new Ski homolog, Fussel-18, specifically expressed in neuronal tissues."
Lab. Invest. 85:1330-1341(2005) [PubMed] [Europe PMC] [Abstract]
"Oligomerization of Evi-1 regulated by the PR domain contributes to recruitment of corepressor CtBP."
Oncogene 24:6165-6173(2005) [PubMed] [Europe PMC] [Abstract]
"PPM1A functions as a Smad phosphatase to terminate TGFbeta signaling."
Cell 125:915-928(2006) [PubMed] [Europe PMC] [Abstract]
"Hematopoiesis controlled by distinct TIF1gamma and Smad4 branches of the TGFbeta pathway."
Cell 125:929-941(2006) [PubMed] [Europe PMC] [Abstract]
"The mechanism of nuclear export of Smad3 involves exportin 4 and Ran."
Mol. Cell. Biol. 26:1318-1332(2006) [PubMed] [Europe PMC] [Abstract]
"Potentiation of Smad-mediated transcriptional activation by the RNA-binding protein RBPMS."
Nucleic Acids Res. 34:6314-6326(2006) [PubMed] [Europe PMC] [Abstract]
"3-Phosphoinositide-dependent PDK1 negatively regulates transforming growth factor-beta-induced signaling in a kinase-dependent manner through physical interaction with Smad proteins."
J. Biol. Chem. 282:12272-12289(2007) [PubMed] [Europe PMC] [Abstract]
"Fussel-15, a novel Ski/Sno homolog protein, antagonizes BMP signaling."
Mol. Cell. Neurosci. 34:603-611(2007) [PubMed] [Europe PMC] [Abstract]
"Smad3 is acetylated by p300/CBP to regulate its transactivation activity."
Oncogene 26:500-508(2007) [PubMed] [Europe PMC] [Abstract]
"TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal."
Nat. Cell Biol. 10:837-848(2008) [PubMed] [Europe PMC] [Abstract]
"Ligand-dependent ubiquitination of Smad3 is regulated by casein kinase 1 gamma 2, an inhibitor of TGF-beta signaling."
Oncogene 27:7235-7247(2008) [PubMed] [Europe PMC] [Abstract]
"A quantitative atlas of mitotic phosphorylation."
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
"Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
"Nuclear export of Smad2 and Smad3 by RanBP3 facilitates termination of TGF-beta signaling."
Dev. Cell 16:345-357(2009) [PubMed] [Europe PMC] [Abstract]
"SKI and MEL1 cooperate to inhibit transforming growth factor-beta signal in gastric cancer cells."
J. Biol. Chem. 284:3334-3344(2009) [PubMed] [Europe PMC] [Abstract]
"Transforming growth factor-{beta}-inducible phosphorylation of Smad3."
J. Biol. Chem. 284:9663-9673(2009) [PubMed] [Europe PMC] [Abstract]
"TMEPAI, a transmembrane TGF-beta-inducible protein, sequesters Smad proteins from active participation in TGF-beta signaling."
Mol. Cell 37:123-134(2010) [PubMed] [Europe PMC] [Abstract]
"IL-37 is a fundamental inhibitor of innate immunity."
Nat. Immunol. 11:1014-1022(2010) [PubMed] [Europe PMC] [Abstract]
"Initial characterization of the human central proteome."
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
"USP15 is a deubiquitylating enzyme for receptor-activated SMADs."
Nat. Cell Biol. 13:1368-1375(2011) [PubMed] [Europe PMC] [Abstract]
"Protein phosphatase 5 modulates SMAD3 function in the transforming growth factor-? pathway."
Cell. Signal. 24:1999-2006(2012) [PubMed] [Europe PMC] [Abstract]
"N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."
Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
"C18 ORF1, a novel negative regulator of transforming growth factor-beta signaling."
J. Biol. Chem. 289:12680-12692(2014) [PubMed] [Europe PMC] [Abstract]
"Fine-tuning of Smad protein function by poly(ADP-ribose) polymerases and poly(ADP-ribose) glycohydrolase during transforming growth factor beta Signaling."
PLoS ONE 9:E103651-E103651(2014) [PubMed] [Europe PMC] [Abstract]
"Crystal structure of a Smad MH1 domain bound to DNA: insights on DNA binding in TGF-beta signaling."
Cell 94:585-594(1998) [PubMed] [Europe PMC] [Abstract]
"Smad3 allostery links TGF-beta receptor kinase activation to transcriptional control."
Genes Dev. 16:1950-1963(2002) [PubMed] [Europe PMC] [Abstract]
"Features of a Smad3 MH1-DNA complex. Roles of water and zinc in DNA binding."
J. Biol. Chem. 278:20327-20331(2003) [PubMed] [Europe PMC] [Abstract]
"Structural basis of heteromeric smad protein assembly in TGF-beta signaling."
Mol. Cell 15:813-823(2004) [PubMed] [Europe PMC] [Abstract]
"The consensus coding sequences of human breast and colorectal cancers."
Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]
"Exome sequencing identifies SMAD3 mutations as a cause of familial thoracic aortic aneurysm and dissection with intracranial and other arterial aneurysms."
Circ. Res. 109:680-686(2011) [PubMed] [Europe PMC] [Abstract]
"Mutations in SMAD3 cause a syndromic form of aortic aneurysms and dissections with early-onset osteoarthritis."
Nat. Genet. 43:121-126(2011) [PubMed] [Europe PMC] [Abstract]