Decorin (DCN)

CSCD; DSPG2; PG40; PGII; PGS2; PG-S2; SLRR1B; Bone proteoglycan II

SPN	U717
HGNC	2705
MGI	94872
PubMed	22194599
RGD	61895
UniProt	P07585
Wiki	Decorin

Decorin is a proteoglycan on average 90 - 140 kilodaltons (kD) in size.It belongs to the small leucine-rich proteoglycan (SLRP) family and consists of a protein core containing leucine repeats with a glycosaminoglycan (GAG) chain consisting of either chondroitin sulfate (CS) or dermatan sulfate (DS). Decorin is a small cellular or pericellular matrix proteoglycan and is closely related in structure to biglycan protein. Decorin and biglycan are thought to be the result of a gene duplication. This protein is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly.
Decorin appears to influence fibrillogenesis, and also interacts with fibronectin, thrombospondin, the complement component C1q, epidermal growth factor receptor (EGFR) and transforming growth factor-beta (TGF-beta).

Organism species: Homo sapiens (Human)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	U717Hu01	Recombinant Decorin (DCN)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Decorin (DCN)	Bioactivity
Antibodies	MU717Hu22	Monoclonal Antibody to Decorin (DCN)	WB; IHC; ICC; IP.
	PU717Hu01	Polyclonal Antibody to Decorin (DCN)	WB; IHC; ICC; IF.
	LU717Hu71	Biotin Linked-Polyclonal Antibody to Decorin (DCN)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Decorin (DCN)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Decorin (DCN)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Decorin (DCN)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Decorin (DCN)	Flow Cytometry;ICC/IF
Assay Kits	KEU717Hu	ELISA Kit for Decorin (DCN)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Decorin (DCN)	CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Decorin (DCN)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Decorin (DCN)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Decorin (DCN)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Decorin (DCN)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Decorin (DCN)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Decorin (DCN)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Decorin (DCN)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Decorin (DCN)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Decorin (DCN)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Decorin (DCN)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Decorin (DCN)	CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Decorin (DCN)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Decorin (DCN)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Decorin (DCN)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Decorin (DCN)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Decorin (DCN)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Decorin (DCN)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Decorin (DCN)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Decorin (DCN)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Decorin (DCN)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Decorin (DCN)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Decorin (DCN)	CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Decorin (DCN)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Decorin (DCN)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Decorin (DCN)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Decorin (DCN)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Decorin (DCN)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Decorin (DCN)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Decorin (DCN)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Decorin (DCN)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Decorin (DCN)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Decorin (DCN)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Decorin (DCN)	CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Decorin (DCN)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Decorin (DCN)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Decorin (DCN)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Decorin (DCN)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Decorin (DCN)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Decorin (DCN)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Decorin (DCN)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Decorin (DCN)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Decorin (DCN)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Decorin (DCN)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Decorin (DCN)	CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Decorin (DCN)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Decorin (DCN)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Decorin (DCN)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Decorin (DCN)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Decorin (DCN)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Decorin (DCN)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Decorin (DCN)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Decorin (DCN)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Decorin (DCN)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Decorin (DCN)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Decorin (DCN)	CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Decorin (DCN)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Decorin (DCN)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Decorin (DCN)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Decorin (DCN)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Decorin (DCN)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Decorin (DCN)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Decorin (DCN)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Decorin (DCN)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Decorin (DCN)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Decorin (DCN)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Decorin (DCN)	CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Decorin (DCN)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Decorin (DCN)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Decorin (DCN)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Decorin (DCN)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Decorin (DCN)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Decorin (DCN)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Decorin (DCN)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Decorin (DCN)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Decorin (DCN)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Decorin (DCN)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Decorin (DCN)	CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Decorin (DCN)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Decorin (DCN)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Decorin (DCN)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Decorin (DCN)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Decorin (DCN)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Decorin (DCN)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Decorin (DCN)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Decorin (DCN)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Decorin (DCN)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Decorin (DCN)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Decorin (DCN)	CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Decorin (DCN)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Decorin (DCN)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Decorin (DCN)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Decorin (DCN)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Decorin (DCN)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Decorin (DCN)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Decorin (DCN)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Decorin (DCN)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Decorin (DCN)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Decorin (DCN)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Decorin (DCN)	CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Decorin (DCN)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Decorin (DCN)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Decorin (DCN)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Decorin (DCN)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Decorin (DCN)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Decorin (DCN)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Decorin (DCN)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Decorin (DCN)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Decorin (DCN)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Decorin (DCN)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Decorin (DCN)	CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Decorin (DCN)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Decorin (DCN)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Decorin (DCN)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Decorin (DCN)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Decorin (DCN)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Decorin (DCN)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Decorin (DCN)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Decorin (DCN)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Decorin (DCN)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Decorin (DCN)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Decorin (DCN)	CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Decorin (DCN)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Decorin (DCN)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Decorin (DCN)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Decorin (DCN)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Decorin (DCN)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Decorin (DCN)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Decorin (DCN)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Decorin (DCN)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Decorin (DCN)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Decorin (DCN)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Decorin (DCN)	CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Decorin (DCN)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Decorin (DCN)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Decorin (DCN)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Decorin (DCN)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Decorin (DCN)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Decorin (DCN)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Decorin (DCN)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Decorin (DCN)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Decorin (DCN)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Decorin (DCN)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Decorin (DCN)	CLIA assay for Antigen Detection

Reference

"Primary structure of an extracellular matrix proteoglycan core protein deduced from cloned cDNA."
Proc. Natl. Acad. Sci. U.S.A. 83:7683-7687(1986) [PubMed] [Europe PMC] [Abstract]

"Human decorin gene: intron-exon junctions and chromosomal localization."
Genomics 15:161-168(1993) [PubMed] [Europe PMC] [Abstract]

"The human decorin gene: intron-exon organization, discovery of two alternatively spliced exons in the 5' untranslated region, and mapping of the gene to chromosome 12q23."
Genomics 15:146-160(1993) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Dermatan sulphate proteoglycans of human articular cartilage. The properties of dermatan sulphate proteoglycans I and II."
Biochem. J. 262:823-827(1989) [PubMed] [Europe PMC] [Abstract]

"Purification and partial characterization of small proteoglycans I and II, bone sialoproteins I and II, and osteonectin from the mineral compartment of developing human bone."
J. Biol. Chem. 262:9702-9708(1987) [PubMed] [Europe PMC] [Abstract]

"Congenital stromal dystrophy of the cornea caused by a mutation in the decorin gene."
Invest. Ophthalmol. Vis. Sci. 46:420-426(2005) [PubMed] [Europe PMC] [Abstract]

"Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
J. Proteome Res. 8:651-661(2009) [PubMed] [Europe PMC] [Abstract]

"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]