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Neurturin (NRTN)
Neurturin (NRTN)
NTN
Neurturin, a potent neurotrophic factor, was purified from Chinese hamster ovary cell-conditioned media by Kotzbauer et al. (1996). It is closely related to glial cell line-derived neurotrophic factor (GDNF). NRTN and GDNF form a distinct TGF-beta subfamily, referred to as TRNs (for 'TGF-beta-related neurotrophins'). GDNF is a ligand for the tyrosine kinase receptor RET. Signaling requires an additional GPI-linked protein, GDNF receptor-alpha (GDNFRA).
NRTN also signals through RET and a GPI-linked coreceptor. Like GDNF, neurturin can promote the survival of numerous neuronal populations, including sympathetic, nodose, and dorsal root ganglion sensory neurons. Heuckeroth et al. (1997) isolated mouse and human genomic neurturin clones.
Organism species: Homo sapiens (Human)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
U675Hu01
Recombinant Neurturin (NRTN) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Neurturin (NRTN) Bioactivity
Antibodies
MU675Hu22
Monoclonal Antibody to Neurturin (NRTN) WB; IHC; ICC; IP.
PU675Hu01
Polyclonal Antibody to Neurturin (NRTN) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Neurturin (NRTN) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Neurturin (NRTN) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Neurturin (NRTN) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Neurturin (NRTN) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Neurturin (NRTN) Flow Cytometry;ICC/IF
Assay Kits
KEU675Hu
ELISA Kit for Neurturin (NRTN) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Neurturin (NRTN) CLIA assay for Antigen Detection
Organism species: Mus musculus (Mouse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Neurturin (NRTN) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Neurturin (NRTN) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Neurturin (NRTN) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Neurturin (NRTN) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Neurturin (NRTN) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Neurturin (NRTN) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Neurturin (NRTN) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Neurturin (NRTN) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Neurturin (NRTN) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Neurturin (NRTN) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Neurturin (NRTN) CLIA assay for Antigen Detection
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Neurturin (NRTN) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Neurturin (NRTN) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Neurturin (NRTN) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Neurturin (NRTN) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Neurturin (NRTN) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Neurturin (NRTN) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Neurturin (NRTN) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Neurturin (NRTN) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Neurturin (NRTN) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Neurturin (NRTN) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Neurturin (NRTN) CLIA assay for Antigen Detection
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Neurturin (NRTN) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Neurturin (NRTN) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Neurturin (NRTN) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Neurturin (NRTN) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Neurturin (NRTN) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Neurturin (NRTN) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Neurturin (NRTN) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Neurturin (NRTN) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Neurturin (NRTN) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Neurturin (NRTN) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Neurturin (NRTN) CLIA assay for Antigen Detection
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Neurturin (NRTN) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Neurturin (NRTN) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Neurturin (NRTN) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Neurturin (NRTN) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Neurturin (NRTN) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Neurturin (NRTN) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Neurturin (NRTN) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Neurturin (NRTN) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Neurturin (NRTN) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Neurturin (NRTN) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Neurturin (NRTN) CLIA assay for Antigen Detection
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Neurturin (NRTN) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Neurturin (NRTN) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Neurturin (NRTN) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Neurturin (NRTN) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Neurturin (NRTN) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Neurturin (NRTN) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Neurturin (NRTN) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Neurturin (NRTN) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Neurturin (NRTN) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Neurturin (NRTN) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Neurturin (NRTN) CLIA assay for Antigen Detection
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Neurturin (NRTN) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Neurturin (NRTN) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Neurturin (NRTN) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Neurturin (NRTN) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Neurturin (NRTN) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Neurturin (NRTN) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Neurturin (NRTN) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Neurturin (NRTN) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Neurturin (NRTN) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Neurturin (NRTN) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Neurturin (NRTN) CLIA assay for Antigen Detection
Organism species: Chicken (Gallus)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Neurturin (NRTN) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Neurturin (NRTN) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Neurturin (NRTN) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Neurturin (NRTN) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Neurturin (NRTN) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Neurturin (NRTN) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Neurturin (NRTN) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Neurturin (NRTN) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Neurturin (NRTN) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Neurturin (NRTN) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Neurturin (NRTN) CLIA assay for Antigen Detection
Organism species: Ovis aries; Ovine (Sheep)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Neurturin (NRTN) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Neurturin (NRTN) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Neurturin (NRTN) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Neurturin (NRTN) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Neurturin (NRTN) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Neurturin (NRTN) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Neurturin (NRTN) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Neurturin (NRTN) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Neurturin (NRTN) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Neurturin (NRTN) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Neurturin (NRTN) CLIA assay for Antigen Detection
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Neurturin (NRTN) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Neurturin (NRTN) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Neurturin (NRTN) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Neurturin (NRTN) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Neurturin (NRTN) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Neurturin (NRTN) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Neurturin (NRTN) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Neurturin (NRTN) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Neurturin (NRTN) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Neurturin (NRTN) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Neurturin (NRTN) CLIA assay for Antigen Detection
Organism species: Cavia (Guinea pig )
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Neurturin (NRTN) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Neurturin (NRTN) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Neurturin (NRTN) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Neurturin (NRTN) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Neurturin (NRTN) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Neurturin (NRTN) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Neurturin (NRTN) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Neurturin (NRTN) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Neurturin (NRTN) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Neurturin (NRTN) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Neurturin (NRTN) CLIA assay for Antigen Detection
Organism species: Equus caballus; Equine (Horse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Neurturin (NRTN) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Neurturin (NRTN) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Neurturin (NRTN) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Neurturin (NRTN) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Neurturin (NRTN) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Neurturin (NRTN) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Neurturin (NRTN) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Neurturin (NRTN) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Neurturin (NRTN) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Neurturin (NRTN) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Neurturin (NRTN) CLIA assay for Antigen Detection
Organism species: Capra hircus; Caprine (Goat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Neurturin (NRTN) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Neurturin (NRTN) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Neurturin (NRTN) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Neurturin (NRTN) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Neurturin (NRTN) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Neurturin (NRTN) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Neurturin (NRTN) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Neurturin (NRTN) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Neurturin (NRTN) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Neurturin (NRTN) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Neurturin (NRTN) CLIA assay for Antigen Detection
Organism species: Pan-species (General)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Neurturin (NRTN) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Neurturin (NRTN) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Neurturin (NRTN) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Neurturin (NRTN) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Neurturin (NRTN) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Neurturin (NRTN) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Neurturin (NRTN) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Neurturin (NRTN) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Neurturin (NRTN) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Neurturin (NRTN) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Neurturin (NRTN) CLIA assay for Antigen Detection
Reference
"Neurturin, a relative of glial-cell-line-derived neurotrophic factor." Nature 384:467-470(1996) [PubMed ] [Europe PMC ] [Abstract ]
"The full-ORF clone resource of the German cDNA consortium." BMC Genomics 8:399-399(2007) [PubMed ] [Europe PMC ] [Abstract ]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." Genome Res. 14:2121-2127(2004) [PubMed ] [Europe PMC ] [Abstract ]
"Mutation of the RET ligand, neurturin, supports multigenic inheritance in Hirschsprung disease." Hum. Mol. Genet. 7:1449-1452(1998) [PubMed ] [Europe PMC ] [Abstract ]
