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Neuregulin 4 (NRG4)
Neuregulin 4 (NRG4)
HRG4; Pro-NRG4; Pro-neuregulin-4, membrane-bound isoform
The neuregulins, including NRG4, activate type-1 growth factor receptors (EGFR) to initiating cell-to-cell signaling through tyrosine phosphorylation.Loss of expression of NRG4 is frequently seen in advanced bladder cancer while increased NRG4 expression correlates to better survival.By searching databases for sequences similar to NRG1, Harari et al. (1999) identified an Nrg4 EST clone originating from a mouse liver cDNA library.
The deduced 115-amino acid protein has a putative N-terminal EGF-like extracellular domain with 2 N-glycosylation sites, followed by a transmembrane region, and a short C-terminal cytoplasmic tail with another N-glycosylation site. It also has 6 cysteines predicted to form 3 disulfide bridges within the extracellular domain.
Organism species: Homo sapiens (Human)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
U670Hu01
Recombinant Neuregulin 4 (NRG4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Neuregulin 4 (NRG4) Bioactivity
Antibodies
MU670Hu21
Monoclonal Antibody to Neuregulin 4 (NRG4) WB; IHC; ICC; IP.
PU670Hu01
Polyclonal Antibody to Neuregulin 4 (NRG4) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) Flow Cytometry;ICC/IF
Assay Kits
KEU670Hu
ELISA Kit for Neuregulin 4 (NRG4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Neuregulin 4 (NRG4) CLIA assay for Antigen Detection
Organism species: Mus musculus (Mouse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
U670Mu01
Recombinant Neuregulin 4 (NRG4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Neuregulin 4 (NRG4) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Neuregulin 4 (NRG4) WB; IHC; ICC; IP.
PU670Mu01
Polyclonal Antibody to Neuregulin 4 (NRG4) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) Flow Cytometry;ICC/IF
Assay Kits
KEU670Mu
ELISA Kit for Neuregulin 4 (NRG4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Neuregulin 4 (NRG4) CLIA assay for Antigen Detection
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Neuregulin 4 (NRG4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Neuregulin 4 (NRG4) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Neuregulin 4 (NRG4) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Neuregulin 4 (NRG4) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Neuregulin 4 (NRG4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Neuregulin 4 (NRG4) CLIA assay for Antigen Detection
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Neuregulin 4 (NRG4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Neuregulin 4 (NRG4) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Neuregulin 4 (NRG4) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Neuregulin 4 (NRG4) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Neuregulin 4 (NRG4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Neuregulin 4 (NRG4) CLIA assay for Antigen Detection
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Neuregulin 4 (NRG4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Neuregulin 4 (NRG4) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Neuregulin 4 (NRG4) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Neuregulin 4 (NRG4) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Neuregulin 4 (NRG4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Neuregulin 4 (NRG4) CLIA assay for Antigen Detection
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Neuregulin 4 (NRG4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Neuregulin 4 (NRG4) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Neuregulin 4 (NRG4) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Neuregulin 4 (NRG4) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Neuregulin 4 (NRG4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Neuregulin 4 (NRG4) CLIA assay for Antigen Detection
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Neuregulin 4 (NRG4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Neuregulin 4 (NRG4) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Neuregulin 4 (NRG4) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Neuregulin 4 (NRG4) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Neuregulin 4 (NRG4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Neuregulin 4 (NRG4) CLIA assay for Antigen Detection
Organism species: Chicken (Gallus)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Neuregulin 4 (NRG4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Neuregulin 4 (NRG4) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Neuregulin 4 (NRG4) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Neuregulin 4 (NRG4) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Neuregulin 4 (NRG4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Neuregulin 4 (NRG4) CLIA assay for Antigen Detection
Organism species: Ovis aries; Ovine (Sheep)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Neuregulin 4 (NRG4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Neuregulin 4 (NRG4) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Neuregulin 4 (NRG4) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Neuregulin 4 (NRG4) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Neuregulin 4 (NRG4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Neuregulin 4 (NRG4) CLIA assay for Antigen Detection
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Neuregulin 4 (NRG4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Neuregulin 4 (NRG4) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Neuregulin 4 (NRG4) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Neuregulin 4 (NRG4) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Neuregulin 4 (NRG4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Neuregulin 4 (NRG4) CLIA assay for Antigen Detection
Organism species: Cavia (Guinea pig )
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Neuregulin 4 (NRG4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Neuregulin 4 (NRG4) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Neuregulin 4 (NRG4) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Neuregulin 4 (NRG4) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Neuregulin 4 (NRG4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Neuregulin 4 (NRG4) CLIA assay for Antigen Detection
Organism species: Equus caballus; Equine (Horse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Neuregulin 4 (NRG4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Neuregulin 4 (NRG4) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Neuregulin 4 (NRG4) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Neuregulin 4 (NRG4) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Neuregulin 4 (NRG4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Neuregulin 4 (NRG4) CLIA assay for Antigen Detection
Organism species: Capra hircus; Caprine (Goat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Neuregulin 4 (NRG4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Neuregulin 4 (NRG4) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Neuregulin 4 (NRG4) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Neuregulin 4 (NRG4) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Neuregulin 4 (NRG4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Neuregulin 4 (NRG4) CLIA assay for Antigen Detection
Organism species: Pan-species (General)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Neuregulin 4 (NRG4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Neuregulin 4 (NRG4) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Neuregulin 4 (NRG4) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Neuregulin 4 (NRG4) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Neuregulin 4 (NRG4) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Neuregulin 4 (NRG4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Neuregulin 4 (NRG4) CLIA assay for Antigen Detection
Reference
"Analysis of the DNA sequence and duplication history of human chromosome 15." Nature 440:671-675(2006) [PubMed ] [Europe PMC ] [Abstract ]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." Genome Res. 14:2121-2127(2004) [PubMed ] [Europe PMC ] [Abstract ]
