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Interferon Regulatory Factor 2 (IRF2)

Interferon regulatory factor 2 isa member of the interferon regulatory transcription factor (IRF) family. IRF2 competitively inhibits the IRF1-mediated transcriptional activation of interferons alpha and beta, and presumably other genes that employ IRF1 for transcription activation. However, IRF2 also functions as a transcriptional activator of histone H4.
Harada et al. (1993) found that when the IRF2 gene was overexpressed in NIH 3T3 cells, the cells became transformed and displayed enhanced tumorigenicity in nude mice. This transformed phenotype was reversed by concomitant expression of the IRF1 gene. Thus, restrained cell growth depends on a balance between these 2 mutually antagonistic transcription factors.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins U664Hu01 Recombinant Interferon Regulatory Factor 2 (IRF2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Interferon Regulatory Factor 2 (IRF2) Bioactivity
Antibodies NONE Monoclonal Antibody to Interferon Regulatory Factor 2 (IRF2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Interferon Regulatory Factor 2 (IRF2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Interferon Regulatory Factor 2 (IRF2) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins U664Mu01 Recombinant Interferon Regulatory Factor 2 (IRF2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Interferon Regulatory Factor 2 (IRF2) Bioactivity
Antibodies NONE Monoclonal Antibody to Interferon Regulatory Factor 2 (IRF2) WB; IHC; ICC; IP.
PU664Mu01 Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Interferon Regulatory Factor 2 (IRF2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Interferon Regulatory Factor 2 (IRF2) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Interferon Regulatory Factor 2 (IRF2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Interferon Regulatory Factor 2 (IRF2) Bioactivity
Antibodies NONE Monoclonal Antibody to Interferon Regulatory Factor 2 (IRF2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Interferon Regulatory Factor 2 (IRF2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Interferon Regulatory Factor 2 (IRF2) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Interferon Regulatory Factor 2 (IRF2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Interferon Regulatory Factor 2 (IRF2) Bioactivity
Antibodies NONE Monoclonal Antibody to Interferon Regulatory Factor 2 (IRF2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Interferon Regulatory Factor 2 (IRF2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Interferon Regulatory Factor 2 (IRF2) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Interferon Regulatory Factor 2 (IRF2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Interferon Regulatory Factor 2 (IRF2) Bioactivity
Antibodies NONE Monoclonal Antibody to Interferon Regulatory Factor 2 (IRF2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Interferon Regulatory Factor 2 (IRF2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Interferon Regulatory Factor 2 (IRF2) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Interferon Regulatory Factor 2 (IRF2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Interferon Regulatory Factor 2 (IRF2) Bioactivity
Antibodies NONE Monoclonal Antibody to Interferon Regulatory Factor 2 (IRF2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Interferon Regulatory Factor 2 (IRF2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Interferon Regulatory Factor 2 (IRF2) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Interferon Regulatory Factor 2 (IRF2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Interferon Regulatory Factor 2 (IRF2) Bioactivity
Antibodies NONE Monoclonal Antibody to Interferon Regulatory Factor 2 (IRF2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Interferon Regulatory Factor 2 (IRF2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Interferon Regulatory Factor 2 (IRF2) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Interferon Regulatory Factor 2 (IRF2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Interferon Regulatory Factor 2 (IRF2) Bioactivity
Antibodies NONE Monoclonal Antibody to Interferon Regulatory Factor 2 (IRF2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Interferon Regulatory Factor 2 (IRF2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Interferon Regulatory Factor 2 (IRF2) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Interferon Regulatory Factor 2 (IRF2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Interferon Regulatory Factor 2 (IRF2) Bioactivity
Antibodies NONE Monoclonal Antibody to Interferon Regulatory Factor 2 (IRF2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Interferon Regulatory Factor 2 (IRF2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Interferon Regulatory Factor 2 (IRF2) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Interferon Regulatory Factor 2 (IRF2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Interferon Regulatory Factor 2 (IRF2) Bioactivity
Antibodies NONE Monoclonal Antibody to Interferon Regulatory Factor 2 (IRF2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Interferon Regulatory Factor 2 (IRF2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Interferon Regulatory Factor 2 (IRF2) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Interferon Regulatory Factor 2 (IRF2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Interferon Regulatory Factor 2 (IRF2) Bioactivity
Antibodies NONE Monoclonal Antibody to Interferon Regulatory Factor 2 (IRF2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Interferon Regulatory Factor 2 (IRF2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Interferon Regulatory Factor 2 (IRF2) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Interferon Regulatory Factor 2 (IRF2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Interferon Regulatory Factor 2 (IRF2) Bioactivity
Antibodies NONE Monoclonal Antibody to Interferon Regulatory Factor 2 (IRF2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Interferon Regulatory Factor 2 (IRF2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Interferon Regulatory Factor 2 (IRF2) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Interferon Regulatory Factor 2 (IRF2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Interferon Regulatory Factor 2 (IRF2) Bioactivity
Antibodies NONE Monoclonal Antibody to Interferon Regulatory Factor 2 (IRF2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Interferon Regulatory Factor 2 (IRF2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Interferon Regulatory Factor 2 (IRF2) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Interferon Regulatory Factor 2 (IRF2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Interferon Regulatory Factor 2 (IRF2) Bioactivity
Antibodies NONE Monoclonal Antibody to Interferon Regulatory Factor 2 (IRF2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Interferon Regulatory Factor 2 (IRF2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Interferon Regulatory Factor 2 (IRF2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Interferon Regulatory Factor 2 (IRF2) CLIA assay for Antigen Detection

Reference

"Sequence of a cDNA coding for human IRF-2."
Nucleic Acids Res. 17:8372-8372(1989) [PubMed] [Europe PMC] [Abstract]

"Human interferon regulatory factor 2 gene. Intron-exon organization and functional analysis of 5'-flanking region."
J. Biol. Chem. 269:5279-5287(1994) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"The integrated activities of IRF-2 (HiNF-M), CDP/cut (HiNF-D) and H4TF-2 (HiNF-P) regulate transcription of a cell cycle controlled human histone H4 gene: mechanistic differences between distinct H4 genes."
Mol. Biol. Rep. 25:1-12(1998) [PubMed] [Europe PMC] [Abstract]

"Molecular characterization of celtix-1, a bromodomain protein interacting with the transcription factor interferon regulatory factor 2."
J. Cell. Physiol. 185:269-279(2000) [PubMed] [Europe PMC] [Abstract]

"Cloning of an interferon regulatory factor 2 isoform with different regulatory ability."
Nucleic Acids Res. 28:4219-4224(2000) [PubMed] [Europe PMC] [Abstract]

"Interferon regulatory factor-2 regulates cell growth through its acetylation."
J. Biol. Chem. 278:25401-25407(2003) [PubMed] [Europe PMC] [Abstract]

"Identification of novel co-repressor molecules for interferon regulatory factor-2."
Nucleic Acids Res. 31:3016-3026(2003) [PubMed] [Europe PMC] [Abstract]

"Interferon regulatory factor 1 (IRF-1) and IRF-2 distinctively up-regulate gene expression and production of interleukin-7 in human intestinal epithelial cells."
Mol. Cell. Biol. 24:6298-6310(2004) [PubMed] [Europe PMC] [Abstract]

"Regulation of IRF2 transcriptional activity by its sumoylation."
Biochem. Biophys. Res. Commun. 372:772-778(2008) [PubMed] [Europe PMC] [Abstract]

"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]