Axis Inhibition Protein (AXIN)
AXIN1
Axin-1 encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin (cadherin-associated protein), beta 1, 88kDa, glycogen synthase kinase 3 beta, protein phosphate 2, and itself. This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The crystal structure of a portion of this protein, alone and in a complex with other proteins, has been resolved. Mutations in this gene have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, and medullablastomas.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Axis Inhibition Protein (AXIN) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Axis Inhibition Protein (AXIN) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Axis Inhibition Protein (AXIN) | WB; IHC; ICC; IP. |
| PU653Hu01 | Polyclonal Antibody to Axis Inhibition Protein (AXIN) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Axis Inhibition Protein (AXIN) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Axis Inhibition Protein (AXIN) | CLIA assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Axis Inhibition Protein (AXIN) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Axis Inhibition Protein (AXIN) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Axis Inhibition Protein (AXIN) | WB; IHC; ICC; IP. |
| PU653Mu01 | Polyclonal Antibody to Axis Inhibition Protein (AXIN) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Axis Inhibition Protein (AXIN) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Axis Inhibition Protein (AXIN) | CLIA assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Axis Inhibition Protein (AXIN) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Axis Inhibition Protein (AXIN) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Axis Inhibition Protein (AXIN) | WB; IHC; ICC; IP. |
| PU653Ra01 | Polyclonal Antibody to Axis Inhibition Protein (AXIN) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Axis Inhibition Protein (AXIN) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Axis Inhibition Protein (AXIN) | CLIA assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Axis Inhibition Protein (AXIN) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Axis Inhibition Protein (AXIN) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Axis Inhibition Protein (AXIN) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Axis Inhibition Protein (AXIN) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Axis Inhibition Protein (AXIN) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Axis Inhibition Protein (AXIN) | CLIA assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Axis Inhibition Protein (AXIN) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Axis Inhibition Protein (AXIN) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Axis Inhibition Protein (AXIN) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Axis Inhibition Protein (AXIN) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Axis Inhibition Protein (AXIN) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Axis Inhibition Protein (AXIN) | CLIA assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Axis Inhibition Protein (AXIN) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Axis Inhibition Protein (AXIN) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Axis Inhibition Protein (AXIN) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Axis Inhibition Protein (AXIN) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Axis Inhibition Protein (AXIN) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Axis Inhibition Protein (AXIN) | CLIA assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Axis Inhibition Protein (AXIN) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Axis Inhibition Protein (AXIN) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Axis Inhibition Protein (AXIN) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Axis Inhibition Protein (AXIN) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Axis Inhibition Protein (AXIN) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Axis Inhibition Protein (AXIN) | CLIA assay for Antigen Detection |
Organism species: Chicken (Gallus)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Axis Inhibition Protein (AXIN) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Axis Inhibition Protein (AXIN) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Axis Inhibition Protein (AXIN) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Axis Inhibition Protein (AXIN) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Axis Inhibition Protein (AXIN) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Axis Inhibition Protein (AXIN) | CLIA assay for Antigen Detection |
Organism species: Ovis aries; Ovine (Sheep)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Axis Inhibition Protein (AXIN) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Axis Inhibition Protein (AXIN) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Axis Inhibition Protein (AXIN) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Axis Inhibition Protein (AXIN) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Axis Inhibition Protein (AXIN) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Axis Inhibition Protein (AXIN) | CLIA assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Axis Inhibition Protein (AXIN) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Axis Inhibition Protein (AXIN) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Axis Inhibition Protein (AXIN) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Axis Inhibition Protein (AXIN) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Axis Inhibition Protein (AXIN) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Axis Inhibition Protein (AXIN) | CLIA assay for Antigen Detection |
Organism species: Cavia (Guinea pig )
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Axis Inhibition Protein (AXIN) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Axis Inhibition Protein (AXIN) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Axis Inhibition Protein (AXIN) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Axis Inhibition Protein (AXIN) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Axis Inhibition Protein (AXIN) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Axis Inhibition Protein (AXIN) | CLIA assay for Antigen Detection |
Organism species: Equus caballus; Equine (Horse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Axis Inhibition Protein (AXIN) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Axis Inhibition Protein (AXIN) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Axis Inhibition Protein (AXIN) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Axis Inhibition Protein (AXIN) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Axis Inhibition Protein (AXIN) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Axis Inhibition Protein (AXIN) | CLIA assay for Antigen Detection |
Organism species: Capra hircus; Caprine (Goat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Axis Inhibition Protein (AXIN) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Axis Inhibition Protein (AXIN) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Axis Inhibition Protein (AXIN) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Axis Inhibition Protein (AXIN) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Axis Inhibition Protein (AXIN) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Axis Inhibition Protein (AXIN) | CLIA assay for Antigen Detection |
Organism species: Pan-species (General)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Axis Inhibition Protein (AXIN) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Axis Inhibition Protein (AXIN) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Axis Inhibition Protein (AXIN) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Axis Inhibition Protein (AXIN) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Axis Inhibition Protein (AXIN) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Axis Inhibition Protein (AXIN) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Axis Inhibition Protein (AXIN) | CLIA assay for Antigen Detection |
Reference
"The mouse Fused locus encodes Axin, an inhibitor of the Wnt signaling pathway that regulates embryonic axis formation."
Cell 90:181-192(1997) [PubMed] [Europe PMC] [Abstract]
"Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16."
Hum. Mol. Genet. 10:339-352(2001) [PubMed] [Europe PMC] [Abstract]
"The sequence and analysis of duplication-rich human chromosome 16."
Nature 432:988-994(2004) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Identification of a domain of Axin that binds to the serine/threonine protein phosphatase 2A and a self-binding domain."
J. Biol. Chem. 274:3439-3445(1999) [PubMed] [Europe PMC] [Abstract]
"AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1."
Nat. Genet. 24:245-250(2000) [PubMed] [Europe PMC] [Abstract]
"Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway."
Mol. Cell 7:801-809(2001) [PubMed] [Europe PMC] [Abstract]
"I-mfa domain proteins interact with Axin and affect its regulation of the Wnt and c-Jun N-terminal kinase signaling pathways."
Mol. Cell. Biol. 22:6393-6405(2002) [PubMed] [Europe PMC] [Abstract]
"Regulation of the Wnt signaling pathway by disabled-2 (Dab2)."
EMBO J. 22:3084-3094(2003) [PubMed] [Europe PMC] [Abstract]
"The DIX domain protein coiled-coil-DIX1 inhibits c-Jun N-terminal kinase activation by Axin and dishevelled through distinct mechanisms."
J. Biol. Chem. 279:39366-39373(2004) [PubMed] [Europe PMC] [Abstract]
"Increased DNA methylation at the AXIN1 gene in a monozygotic twin from a pair discordant for a caudal duplication anomaly."
Am. J. Hum. Genet. 79:155-162(2006) [PubMed] [Europe PMC] [Abstract]
"Axin is a scaffold protein in TGF-beta signaling that promotes degradation of Smad7 by Arkadia."
EMBO J. 25:1646-1658(2006) [PubMed] [Europe PMC] [Abstract]
"Daxx cooperates with the Axin/HIPK2/p53 complex to induce cell death."
Cancer Res. 67:66-74(2007) [PubMed] [Europe PMC] [Abstract]
"Protein phosphatase 1 regulates assembly and function of the beta-catenin degradation complex."
EMBO J. 26:1511-1521(2007) [PubMed] [Europe PMC] [Abstract]
"SUMOylation target sites at the C terminus protect Axin from ubiquitination and confer protein stability."
FASEB J. 22:3785-3794(2008) [PubMed] [Europe PMC] [Abstract]
"A quantitative atlas of mitotic phosphorylation."
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
"Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling."
Nature 461:614-620(2009) [PubMed] [Europe PMC] [Abstract]
"The Ubiquitin specific protease USP34 regulates Axin stability and Wnt/beta-catenin signaling."
Mol. Cell. Biol. 31:2053-2065(2011) [PubMed] [Europe PMC] [Abstract]
"RNF146 is a poly(ADP-ribose)-directed E3 ligase that regulates axin degradation and Wnt signalling."
Nat. Cell Biol. 13:623-629(2011) [PubMed] [Europe PMC] [Abstract]
"Ubiquitin ligase RNF146 regulates tankyrase and Axin to promote Wnt signaling."
PLoS ONE 6:E22595-E22595(2011) [PubMed] [Europe PMC] [Abstract]
"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
"Structural basis of the axin-adenomatous polyposis coli interaction."
EMBO J. 19:2270-2279(2000) [PubMed] [Europe PMC] [Abstract]
"Structural basis for recruitment of glycogen synthase kinase 3beta to the axin-APC scaffold complex."
EMBO J. 22:494-501(2003) [PubMed] [Europe PMC] [Abstract]
"Mutational spectrum of beta-catenin, AXIN1, and AXIN2 in hepatocellular carcinomas and hepatoblastomas."
Oncogene 21:4863-4871(2002) [PubMed] [Europe PMC] [Abstract]