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Methyl CpG Binding Domain Protein 2 (MBD2)

DMTase; NY-CO-41; Demethylase; Methyl-CpG-binding protein MBD2

DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters.
Methyl-CpG-binding domain protein 2 may function as a mediator of the biological consequences of the methylation signal. It is also reported that the this protein functions as a demethylase to activate transcription, as DNA methylation causes gene silencing.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins U637Hu01 Recombinant Methyl CpG Binding Domain Protein 2 (MBD2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Methyl CpG Binding Domain Protein 2 (MBD2) Bioactivity
Antibodies NONE Monoclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Methyl CpG Binding Domain Protein 2 (MBD2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Methyl CpG Binding Domain Protein 2 (MBD2) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Methyl CpG Binding Domain Protein 2 (MBD2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Methyl CpG Binding Domain Protein 2 (MBD2) Bioactivity
Antibodies NONE Monoclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Methyl CpG Binding Domain Protein 2 (MBD2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Methyl CpG Binding Domain Protein 2 (MBD2) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Methyl CpG Binding Domain Protein 2 (MBD2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Methyl CpG Binding Domain Protein 2 (MBD2) Bioactivity
Antibodies NONE Monoclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Methyl CpG Binding Domain Protein 2 (MBD2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Methyl CpG Binding Domain Protein 2 (MBD2) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Methyl CpG Binding Domain Protein 2 (MBD2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Methyl CpG Binding Domain Protein 2 (MBD2) Bioactivity
Antibodies NONE Monoclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Methyl CpG Binding Domain Protein 2 (MBD2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Methyl CpG Binding Domain Protein 2 (MBD2) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Methyl CpG Binding Domain Protein 2 (MBD2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Methyl CpG Binding Domain Protein 2 (MBD2) Bioactivity
Antibodies NONE Monoclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Methyl CpG Binding Domain Protein 2 (MBD2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Methyl CpG Binding Domain Protein 2 (MBD2) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Methyl CpG Binding Domain Protein 2 (MBD2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Methyl CpG Binding Domain Protein 2 (MBD2) Bioactivity
Antibodies NONE Monoclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Methyl CpG Binding Domain Protein 2 (MBD2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Methyl CpG Binding Domain Protein 2 (MBD2) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Methyl CpG Binding Domain Protein 2 (MBD2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Methyl CpG Binding Domain Protein 2 (MBD2) Bioactivity
Antibodies NONE Monoclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Methyl CpG Binding Domain Protein 2 (MBD2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Methyl CpG Binding Domain Protein 2 (MBD2) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Methyl CpG Binding Domain Protein 2 (MBD2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Methyl CpG Binding Domain Protein 2 (MBD2) Bioactivity
Antibodies NONE Monoclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Methyl CpG Binding Domain Protein 2 (MBD2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Methyl CpG Binding Domain Protein 2 (MBD2) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Methyl CpG Binding Domain Protein 2 (MBD2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Methyl CpG Binding Domain Protein 2 (MBD2) Bioactivity
Antibodies NONE Monoclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Methyl CpG Binding Domain Protein 2 (MBD2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Methyl CpG Binding Domain Protein 2 (MBD2) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Methyl CpG Binding Domain Protein 2 (MBD2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Methyl CpG Binding Domain Protein 2 (MBD2) Bioactivity
Antibodies NONE Monoclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Methyl CpG Binding Domain Protein 2 (MBD2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Methyl CpG Binding Domain Protein 2 (MBD2) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Methyl CpG Binding Domain Protein 2 (MBD2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Methyl CpG Binding Domain Protein 2 (MBD2) Bioactivity
Antibodies NONE Monoclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Methyl CpG Binding Domain Protein 2 (MBD2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Methyl CpG Binding Domain Protein 2 (MBD2) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Methyl CpG Binding Domain Protein 2 (MBD2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Methyl CpG Binding Domain Protein 2 (MBD2) Bioactivity
Antibodies NONE Monoclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Methyl CpG Binding Domain Protein 2 (MBD2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Methyl CpG Binding Domain Protein 2 (MBD2) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Methyl CpG Binding Domain Protein 2 (MBD2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Methyl CpG Binding Domain Protein 2 (MBD2) Bioactivity
Antibodies NONE Monoclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Methyl CpG Binding Domain Protein 2 (MBD2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Methyl CpG Binding Domain Protein 2 (MBD2) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Methyl CpG Binding Domain Protein 2 (MBD2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Methyl CpG Binding Domain Protein 2 (MBD2) Bioactivity
Antibodies NONE Monoclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Methyl CpG Binding Domain Protein 2 (MBD2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Methyl CpG Binding Domain Protein 2 (MBD2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Methyl CpG Binding Domain Protein 2 (MBD2) CLIA assay for Antigen Detection

Reference

"Identification and characterization of a family of mammalian methyl-CpG binding proteins."
Mol. Cell. Biol. 18:6538-6547(1998) [PubMed] [Europe PMC] [Abstract]

"Genomic structure and chromosomal mapping of the murine and human mbd1, mbd2, mbd3, and mbd4 genes."
Mamm. Genome 10:906-912(1999) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"A mammalian protein with specific demethylase activity for mCpG DNA."
Nature 397:579-583(1999) [PubMed] [Europe PMC] [Abstract]

"MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex."
Nat. Genet. 23:58-61(1999) [PubMed] [Europe PMC] [Abstract]

"MBD2-MBD3 complex binds to hemi-methylated DNA and forms a complex containing DNMT1 at the replication foci in late S phase."
Genes Cells 5:677-688(2000) [PubMed] [Europe PMC] [Abstract]

"The minimal repression domain of MBD2b overlaps with the methyl-CpG-binding domain and binds directly to Sin3A."
J. Biol. Chem. 275:34963-34967(2000) [PubMed] [Europe PMC] [Abstract]

"Stable histone deacetylase complexes distinguished by the presence of SANT domain proteins CoREST/kiaa0071 and Mta-L1."
J. Biol. Chem. 276:6817-6824(2001) [PubMed] [Europe PMC] [Abstract]

"Involvement of a novel zinc finger protein, MIZF, in transcriptional repression by interacting with a methyl-CpG-binding protein, MBD2."
J. Biol. Chem. 276:42632-42638(2001) [PubMed] [Europe PMC] [Abstract]

"Two highly related p66 proteins comprise a new family of potent transcriptional repressors interacting with MBD2 and MBD3."
J. Biol. Chem. 277:40958-40966(2002) [PubMed] [Europe PMC] [Abstract]

"MBDin, a novel MBD2-interacting protein, relieves MBD2 repression potential and reactivates transcription from methylated promoters."
Mol. Cell. Biol. 23:1656-1665(2003) [PubMed] [Europe PMC] [Abstract]

"Antithetic effects of MBD2a on gene regulation."
Mol. Cell. Biol. 23:2645-2657(2003) [PubMed] [Europe PMC] [Abstract]

"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]

"p66alpha and p66beta of the Mi-2/NuRD complex mediate MBD2 and histone interaction."
Nucleic Acids Res. 34:397-406(2006) [PubMed] [Europe PMC] [Abstract]

"A quantitative atlas of mitotic phosphorylation."
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]

"Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]

"Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]

"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]

"Probing the dynamic distribution of bound states for methylcytosine-binding domains on DNA."
J. Biol. Chem. 289:1294-1302(2014) [PubMed] [Europe PMC] [Abstract]

"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]

"p66Alpha-MBD2 coiled-coil interaction and recruitment of Mi-2 are critical for globin gene silencing by the MBD2-NuRD complex."
Proc. Natl. Acad. Sci. U.S.A. 108:7487-7492(2011) [PubMed] [Europe PMC] [Abstract]