Cortactin (CTTN)
EMS1; Cortical Actin binding Protein; Src substrate cortactin; Amplaxin; Oncogene EMS1
Cortactin is a monomeric protein located in the cytoplasm of cells that can be activated by external stimuli to promote polymerization and rearrangement of the actin cytoskeleton, especially the actin cortex around the cellular periphery. It is present in all cell types. When activated, it will recruit Arp2/3 complex proteins to existing actin microfilaments, facilitating and stabilizing nucleation sites for actin branching. Cortactin is important in promoting lamellipodia formation, invadopodia formation, cell migration, and endocytosis.Cortactin is a thin, elongated monomer that consists of an amino-terminal acidic (NTA) region; 37-residue-long segments that are highly conserved among cortactin proteins of all species and which are repeated up to 6.5 times in tandem (ldquo;cortactin repeats rdquo;); a proline-rich region; and an SH3 domain.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU611Hu01 | Recombinant Cortactin (CTTN) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU611Hu01 | Monoclonal Antibody to Cortactin (CTTN) | WB; IHC; ICC; IP. |
| PAU611Hu01 | Polyclonal Antibody to Cortactin (CTTN) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU611Hu01 | CLIA Kit for Cortactin (CTTN) | CLIA assay for Antigen Detection |
| ELU611Hu01 | ELISA Kit for Cortactin (CTTN) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU611Mu01 | Recombinant Cortactin (CTTN) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU611Mu01 | Monoclonal Antibody to Cortactin (CTTN) | WB; IHC; ICC; IP. |
| PAU611Mu01 | Polyclonal Antibody to Cortactin (CTTN) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU611Mu01 | CLIA Kit for Cortactin (CTTN) | CLIA assay for Antigen Detection |
| ELU611Mu01 | ELISA Kit for Cortactin (CTTN) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU611Ra01 | Recombinant Cortactin (CTTN) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU611Ra01 | Monoclonal Antibody to Cortactin (CTTN) | WB; IHC; ICC; IP. |
| PAU611Ra01 | Polyclonal Antibody to Cortactin (CTTN) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU611Ra01 | CLIA Kit for Cortactin (CTTN) | CLIA assay for Antigen Detection |
| ELU611Ra01 | ELISA Kit for Cortactin (CTTN) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU611Ca01 | Recombinant Cortactin (CTTN) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU611Ca01 | Monoclonal Antibody to Cortactin (CTTN) | WB; IHC; ICC; IP. |
| PAU611Ca01 | Polyclonal Antibody to Cortactin (CTTN) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU611Ca01 | CLIA Kit for Cortactin (CTTN) | CLIA assay for Antigen Detection |
| ELU611Ca01 | ELISA Kit for Cortactin (CTTN) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU611Po01 | Recombinant Cortactin (CTTN) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU611Po01 | Monoclonal Antibody to Cortactin (CTTN) | WB; IHC; ICC; IP. |
| PAU611Po01 | Polyclonal Antibody to Cortactin (CTTN) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU611Po01 | CLIA Kit for Cortactin (CTTN) | CLIA assay for Antigen Detection |
| ELU611Po01 | ELISA Kit for Cortactin (CTTN) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU611Bo01 | Recombinant Cortactin (CTTN) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU611Bo01 | Monoclonal Antibody to Cortactin (CTTN) | WB; IHC; ICC; IP. |
| PAU611Bo01 | Polyclonal Antibody to Cortactin (CTTN) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU611Bo01 | CLIA Kit for Cortactin (CTTN) | CLIA assay for Antigen Detection |
| ELU611Bo01 | ELISA Kit for Cortactin (CTTN) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU611Rb01 | Recombinant Cortactin (CTTN) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU611Rb01 | Monoclonal Antibody to Cortactin (CTTN) | WB; IHC; ICC; IP. |
| PAU611Rb01 | Polyclonal Antibody to Cortactin (CTTN) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU611Rb01 | CLIA Kit for Cortactin (CTTN) | CLIA assay for Antigen Detection |
| ELU611Rb01 | ELISA Kit for Cortactin (CTTN) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU611Mo01 | Recombinant Cortactin (CTTN) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU611Mo01 | Monoclonal Antibody to Cortactin (CTTN) | WB; IHC; ICC; IP. |
| PAU611Mo01 | Polyclonal Antibody to Cortactin (CTTN) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU611Mo01 | CLIA Kit for Cortactin (CTTN) | CLIA assay for Antigen Detection |
| ELU611Mo01 | ELISA Kit for Cortactin (CTTN) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
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Submitted (NOV-2005) to the PDB data bank
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