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Heterogeneous Nuclear Ribonucleoprotein A1 (HNRPA1)

HNRNPA1; hnRNP-A1; Helix-destabilizing protein; Single-strand RNA-binding protein; hnRNP core protein A1; Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed

Heterogeneous nuclear ribonucleoprotein A1  belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). This protein is exported from the nucleus, probably bound to mRNA, and is immediately re-imported. Its M9 domain acts as both a nuclear localization and nuclear export signal. The encoded protein is involved in the packaging of pre-mRNA into hnRNP particles, transport of poly A mRNA from the nucleus to the cytoplasm, and may modulate splice site selection. It is also thought have a primary role in the formation of specific myometrial protein species in parturition. Multiple alternatively spliced transcript variants have been found for this gene but only two transcripts are fully described. These variants have multiple alternative transcription initiation sites and multiple polyA sites.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU593Hu01 Recombinant Heterogeneous Nuclear Ribonucleoprotein A1 (HNRPA1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU593Hu01 Monoclonal Antibody to Heterogeneous Nuclear Ribonucleoprotein A1 (HNRPA1) WB; IHC; ICC; IP.
PAU593Hu01 Polyclonal Antibody to Heterogeneous Nuclear Ribonucleoprotein A1 (HNRPA1) WB; IHC; ICC; IF.
Assay Kits CLU593Hu01 CLIA Kit for Heterogeneous Nuclear Ribonucleoprotein A1 (HNRPA1) CLIA assay for Antigen Detection
ELU593Hu01 ELISA Kit for Heterogeneous Nuclear Ribonucleoprotein A1 (HNRPA1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU593Mu01 Recombinant Heterogeneous Nuclear Ribonucleoprotein A1 (HNRPA1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU593Mu01 Monoclonal Antibody to Heterogeneous Nuclear Ribonucleoprotein A1 (HNRPA1) WB; IHC; ICC; IP.
PAU593Mu01 Polyclonal Antibody to Heterogeneous Nuclear Ribonucleoprotein A1 (HNRPA1) WB; IHC; ICC; IF.
Assay Kits CLU593Mu01 CLIA Kit for Heterogeneous Nuclear Ribonucleoprotein A1 (HNRPA1) CLIA assay for Antigen Detection
ELU593Mu01 ELISA Kit for Heterogeneous Nuclear Ribonucleoprotein A1 (HNRPA1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU593Ra01 Recombinant Heterogeneous Nuclear Ribonucleoprotein A1 (HNRPA1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU593Ra01 Monoclonal Antibody to Heterogeneous Nuclear Ribonucleoprotein A1 (HNRPA1) WB; IHC; ICC; IP.
PAU593Ra01 Polyclonal Antibody to Heterogeneous Nuclear Ribonucleoprotein A1 (HNRPA1) WB; IHC; ICC; IF.
Assay Kits CLU593Ra01 CLIA Kit for Heterogeneous Nuclear Ribonucleoprotein A1 (HNRPA1) CLIA assay for Antigen Detection
ELU593Ra01 ELISA Kit for Heterogeneous Nuclear Ribonucleoprotein A1 (HNRPA1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU593Ca01 Recombinant Heterogeneous Nuclear Ribonucleoprotein A1 (HNRPA1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU593Ca01 Monoclonal Antibody to Heterogeneous Nuclear Ribonucleoprotein A1 (HNRPA1) WB; IHC; ICC; IP.
PAU593Ca01 Polyclonal Antibody to Heterogeneous Nuclear Ribonucleoprotein A1 (HNRPA1) WB; IHC; ICC; IF.
Assay Kits CLU593Ca01 CLIA Kit for Heterogeneous Nuclear Ribonucleoprotein A1 (HNRPA1) CLIA assay for Antigen Detection
ELU593Ca01 ELISA Kit for Heterogeneous Nuclear Ribonucleoprotein A1 (HNRPA1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU593Po01 Recombinant Heterogeneous Nuclear Ribonucleoprotein A1 (HNRPA1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU593Po01 Monoclonal Antibody to Heterogeneous Nuclear Ribonucleoprotein A1 (HNRPA1) WB; IHC; ICC; IP.
PAU593Po01 Polyclonal Antibody to Heterogeneous Nuclear Ribonucleoprotein A1 (HNRPA1) WB; IHC; ICC; IF.
Assay Kits CLU593Po01 CLIA Kit for Heterogeneous Nuclear Ribonucleoprotein A1 (HNRPA1) CLIA assay for Antigen Detection
ELU593Po01 ELISA Kit for Heterogeneous Nuclear Ribonucleoprotein A1 (HNRPA1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU593Bo01 Recombinant Heterogeneous Nuclear Ribonucleoprotein A1 (HNRPA1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU593Bo01 Monoclonal Antibody to Heterogeneous Nuclear Ribonucleoprotein A1 (HNRPA1) WB; IHC; ICC; IP.
PAU593Bo01 Polyclonal Antibody to Heterogeneous Nuclear Ribonucleoprotein A1 (HNRPA1) WB; IHC; ICC; IF.
Assay Kits CLU593Bo01 CLIA Kit for Heterogeneous Nuclear Ribonucleoprotein A1 (HNRPA1) CLIA assay for Antigen Detection
ELU593Bo01 ELISA Kit for Heterogeneous Nuclear Ribonucleoprotein A1 (HNRPA1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU593Rb01 Recombinant Heterogeneous Nuclear Ribonucleoprotein A1 (HNRPA1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU593Rb01 Monoclonal Antibody to Heterogeneous Nuclear Ribonucleoprotein A1 (HNRPA1) WB; IHC; ICC; IP.
PAU593Rb01 Polyclonal Antibody to Heterogeneous Nuclear Ribonucleoprotein A1 (HNRPA1) WB; IHC; ICC; IF.
Assay Kits CLU593Rb01 CLIA Kit for Heterogeneous Nuclear Ribonucleoprotein A1 (HNRPA1) CLIA assay for Antigen Detection
ELU593Rb01 ELISA Kit for Heterogeneous Nuclear Ribonucleoprotein A1 (HNRPA1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU593Mo01 Recombinant Heterogeneous Nuclear Ribonucleoprotein A1 (HNRPA1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU593Mo01 Monoclonal Antibody to Heterogeneous Nuclear Ribonucleoprotein A1 (HNRPA1) WB; IHC; ICC; IP.
PAU593Mo01 Polyclonal Antibody to Heterogeneous Nuclear Ribonucleoprotein A1 (HNRPA1) WB; IHC; ICC; IF.
Assay Kits CLU593Mo01 CLIA Kit for Heterogeneous Nuclear Ribonucleoprotein A1 (HNRPA1) CLIA assay for Antigen Detection
ELU593Mo01 ELISA Kit for Heterogeneous Nuclear Ribonucleoprotein A1 (HNRPA1) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"Isolation of an active gene encoding human hnRNP protein A1. Evidence for alternative splicing."
J. Mol. Biol. 207:491-503(1989) [PubMed] [Europe PMC] [Abstract]

"cDNA cloning of human hnRNP protein A1 reveals the existence of multiple mRNA isoforms."
Nucleic Acids Res. 16:3751-3770(1988) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"The finished DNA sequence of human chromosome 12."
Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Mammalian single-stranded DNA binding protein UP I is derived from the hnRNP core protein A1."
EMBO J. 5:2267-2273(1986) [PubMed] [Europe PMC] [Abstract]

, Submitted (DEC-2008) to UniProtKB