Bcl2 Modifying Factor (BMF)

SPN	U515
HGNC	24132
MGI	2176433
PubMed	21673109
RGD	628658
UniProt	Q96LC9
Wiki	BMF_(gene

Bcl-2-modifying factor is a protein belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities.

This protein contains a single BCL2 homology domain 3 (BH3), and has been shown to bind BCL2 proteins and function as an apoptotic activator. This protein is found to be sequestered to myosin V motors by its association with dynein light chain 2, which may be important for sensing intracellular damage and triggering apoptosis. Alternatively spliced transcript variants encoding different isoforms have been identified.

Organism species: Homo sapiens (Human)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	U515Hu01	Recombinant Bcl2 Modifying Factor (BMF)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Bcl2 Modifying Factor (BMF)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Bcl2 Modifying Factor (BMF)	WB; IHC; ICC; IP.
	PU515Hu01	Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Bcl2 Modifying Factor (BMF)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Bcl2 Modifying Factor (BMF)	CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Bcl2 Modifying Factor (BMF)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Bcl2 Modifying Factor (BMF)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Bcl2 Modifying Factor (BMF)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Bcl2 Modifying Factor (BMF)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Bcl2 Modifying Factor (BMF)	CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Bcl2 Modifying Factor (BMF)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Bcl2 Modifying Factor (BMF)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Bcl2 Modifying Factor (BMF)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Bcl2 Modifying Factor (BMF)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Bcl2 Modifying Factor (BMF)	CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Bcl2 Modifying Factor (BMF)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Bcl2 Modifying Factor (BMF)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Bcl2 Modifying Factor (BMF)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Bcl2 Modifying Factor (BMF)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Bcl2 Modifying Factor (BMF)	CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Bcl2 Modifying Factor (BMF)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Bcl2 Modifying Factor (BMF)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Bcl2 Modifying Factor (BMF)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Bcl2 Modifying Factor (BMF)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Bcl2 Modifying Factor (BMF)	CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Bcl2 Modifying Factor (BMF)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Bcl2 Modifying Factor (BMF)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Bcl2 Modifying Factor (BMF)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Bcl2 Modifying Factor (BMF)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Bcl2 Modifying Factor (BMF)	CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Bcl2 Modifying Factor (BMF)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Bcl2 Modifying Factor (BMF)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Bcl2 Modifying Factor (BMF)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Bcl2 Modifying Factor (BMF)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Bcl2 Modifying Factor (BMF)	CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Bcl2 Modifying Factor (BMF)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Bcl2 Modifying Factor (BMF)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Bcl2 Modifying Factor (BMF)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Bcl2 Modifying Factor (BMF)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Bcl2 Modifying Factor (BMF)	CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Bcl2 Modifying Factor (BMF)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Bcl2 Modifying Factor (BMF)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Bcl2 Modifying Factor (BMF)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Bcl2 Modifying Factor (BMF)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Bcl2 Modifying Factor (BMF)	CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Bcl2 Modifying Factor (BMF)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Bcl2 Modifying Factor (BMF)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Bcl2 Modifying Factor (BMF)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Bcl2 Modifying Factor (BMF)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Bcl2 Modifying Factor (BMF)	CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Bcl2 Modifying Factor (BMF)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Bcl2 Modifying Factor (BMF)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Bcl2 Modifying Factor (BMF)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Bcl2 Modifying Factor (BMF)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Bcl2 Modifying Factor (BMF)	CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Bcl2 Modifying Factor (BMF)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Bcl2 Modifying Factor (BMF)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Bcl2 Modifying Factor (BMF)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Bcl2 Modifying Factor (BMF)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Bcl2 Modifying Factor (BMF)	CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Bcl2 Modifying Factor (BMF)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Bcl2 Modifying Factor (BMF)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Bcl2 Modifying Factor (BMF)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Bcl2 Modifying Factor (BMF)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Bcl2 Modifying Factor (BMF)	CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Bcl2 Modifying Factor (BMF)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Bcl2 Modifying Factor (BMF)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Bcl2 Modifying Factor (BMF)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Bcl2 Modifying Factor (BMF)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Bcl2 Modifying Factor (BMF)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Bcl2 Modifying Factor (BMF)	CLIA assay for Antigen Detection

Reference

"Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis."
Science 293:1829-1832(2001) [PubMed] [Europe PMC] [Abstract]

"Expression and transcriptional regulation of functionally distinct Bmf isoforms in B-chronic lymphocytic leukemia cells."
Leukemia 18:41-47(2004) [PubMed] [Europe PMC] [Abstract]

"Characterization of long cDNA clones from human adult spleen."
DNA Res. 7:357-366(2000) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]