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Bradykinin Receptor B2 (BDKRB2)

BDKR-B2; B2R; BK2; BKR2; BRB2

Bradykinin receptor B2 (B2) is a g-protein coupled receptor for bradykinin, encoded by the BDKRB2. The B2 receptor is a G protein-coupled receptor, probably coupled to Gq and Gi. Gq stimulates phospholipase C to increase intracellular free calcium and Gi inhibits adenylate cyclase. Furthermore, the receptor stimulates the mitogen-activated protein kinase pathways. It is ubiquitously and constitutively expressed in healthy tissues.
The B2 receptor forms a complex with angiotensin converting enzyme (ACE), and this is thought to play a role in cross-talk between the renin-angiotensin system (RAS) and the kinin-kallikrein system (KKS). The heptapeptide angiotensin 1-7 (A1-7) also potentiates bradykinin action on B2 receptors.Kallidin also signals through the B2 receptor.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Bradykinin Receptor B2 (BDKRB2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Bradykinin Receptor B2 (BDKRB2) Bioactivity
Antibodies NONE Monoclonal Antibody to Bradykinin Receptor B2 (BDKRB2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Bradykinin Receptor B2 (BDKRB2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Bradykinin Receptor B2 (BDKRB2) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Bradykinin Receptor B2 (BDKRB2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Bradykinin Receptor B2 (BDKRB2) Bioactivity
Antibodies NONE Monoclonal Antibody to Bradykinin Receptor B2 (BDKRB2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Bradykinin Receptor B2 (BDKRB2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Bradykinin Receptor B2 (BDKRB2) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins U503Ra01 Recombinant Bradykinin Receptor B2 (BDKRB2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Bradykinin Receptor B2 (BDKRB2) Bioactivity
Antibodies MU503Ra21 Monoclonal Antibody to Bradykinin Receptor B2 (BDKRB2) WB; IHC; ICC; IP.
PU503Ra01 Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) Flow Cytometry;ICC/IF
Assay Kits KEU503Ra ELISA Kit for Bradykinin Receptor B2 (BDKRB2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Bradykinin Receptor B2 (BDKRB2) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Bradykinin Receptor B2 (BDKRB2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Bradykinin Receptor B2 (BDKRB2) Bioactivity
Antibodies NONE Monoclonal Antibody to Bradykinin Receptor B2 (BDKRB2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Bradykinin Receptor B2 (BDKRB2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Bradykinin Receptor B2 (BDKRB2) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Bradykinin Receptor B2 (BDKRB2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Bradykinin Receptor B2 (BDKRB2) Bioactivity
Antibodies NONE Monoclonal Antibody to Bradykinin Receptor B2 (BDKRB2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Bradykinin Receptor B2 (BDKRB2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Bradykinin Receptor B2 (BDKRB2) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Bradykinin Receptor B2 (BDKRB2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Bradykinin Receptor B2 (BDKRB2) Bioactivity
Antibodies NONE Monoclonal Antibody to Bradykinin Receptor B2 (BDKRB2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Bradykinin Receptor B2 (BDKRB2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Bradykinin Receptor B2 (BDKRB2) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Bradykinin Receptor B2 (BDKRB2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Bradykinin Receptor B2 (BDKRB2) Bioactivity
Antibodies NONE Monoclonal Antibody to Bradykinin Receptor B2 (BDKRB2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Bradykinin Receptor B2 (BDKRB2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Bradykinin Receptor B2 (BDKRB2) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Bradykinin Receptor B2 (BDKRB2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Bradykinin Receptor B2 (BDKRB2) Bioactivity
Antibodies NONE Monoclonal Antibody to Bradykinin Receptor B2 (BDKRB2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Bradykinin Receptor B2 (BDKRB2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Bradykinin Receptor B2 (BDKRB2) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Bradykinin Receptor B2 (BDKRB2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Bradykinin Receptor B2 (BDKRB2) Bioactivity
Antibodies NONE Monoclonal Antibody to Bradykinin Receptor B2 (BDKRB2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Bradykinin Receptor B2 (BDKRB2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Bradykinin Receptor B2 (BDKRB2) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Bradykinin Receptor B2 (BDKRB2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Bradykinin Receptor B2 (BDKRB2) Bioactivity
Antibodies NONE Monoclonal Antibody to Bradykinin Receptor B2 (BDKRB2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Bradykinin Receptor B2 (BDKRB2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Bradykinin Receptor B2 (BDKRB2) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Bradykinin Receptor B2 (BDKRB2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Bradykinin Receptor B2 (BDKRB2) Bioactivity
Antibodies NONE Monoclonal Antibody to Bradykinin Receptor B2 (BDKRB2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Bradykinin Receptor B2 (BDKRB2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Bradykinin Receptor B2 (BDKRB2) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Bradykinin Receptor B2 (BDKRB2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Bradykinin Receptor B2 (BDKRB2) Bioactivity
Antibodies NONE Monoclonal Antibody to Bradykinin Receptor B2 (BDKRB2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Bradykinin Receptor B2 (BDKRB2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Bradykinin Receptor B2 (BDKRB2) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Bradykinin Receptor B2 (BDKRB2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Bradykinin Receptor B2 (BDKRB2) Bioactivity
Antibodies NONE Monoclonal Antibody to Bradykinin Receptor B2 (BDKRB2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Bradykinin Receptor B2 (BDKRB2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Bradykinin Receptor B2 (BDKRB2) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Bradykinin Receptor B2 (BDKRB2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Bradykinin Receptor B2 (BDKRB2) Bioactivity
Antibodies NONE Monoclonal Antibody to Bradykinin Receptor B2 (BDKRB2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Bradykinin Receptor B2 (BDKRB2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Bradykinin Receptor B2 (BDKRB2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Bradykinin Receptor B2 (BDKRB2) CLIA assay for Antigen Detection

Reference

"Cloning and pharmacological characterization of a human bradykinin (BK-2) receptor."
Biochem. Biophys. Res. Commun. 184:260-268(1992) [PubMed] [Europe PMC] [Abstract]

"Human bradykinin B2 receptor: nucleotide sequence analysis and assignment to chromosome 14."
Genomics 15:435-438(1993) [PubMed] [Europe PMC] [Abstract]

"Cloned murine bradykinin receptor exhibits a mixed B1 and B2 pharmacological selectivity."
Mol. Pharmacol. 44:346-355(1993) [PubMed] [Europe PMC] [Abstract]

"Molecular cloning, functional expression and pharmacological characterization of a human bradykinin B2 receptor gene."
Biochem. Biophys. Res. Commun. 187:1306-1313(1992) [PubMed] [Europe PMC] [Abstract]

"Structure and chromosomal localization of the gene (BDKRB2) encoding human bradykinin B2 receptor."
Genomics 23:362-369(1994) [PubMed] [Europe PMC] [Abstract]

"Identification of polymorphic sites of the human bradykinin B2 receptor gene."
Biochem. Biophys. Res. Commun. 211:234-240(1995) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Structure of the bradykinin B2 receptors' amino terminus."
Biochemistry 35:7514-7519(1996) [PubMed] [Europe PMC] [Abstract]

"Regulation of G protein-coupled receptor activities by the platelet-endothelial cell adhesion molecule, PECAM-1."
Biochemistry 47:9029-9039(2008) [PubMed] [Europe PMC] [Abstract]

"Determination of bradykinin B2 receptor in vivo phosphorylation sites and their role in receptor function."
J. Biol. Chem. 276:40431-40440(2001) [PubMed] [Europe PMC] [Abstract]