Chibby Homolog 1 (CBY1)
CBY; PGEA1; PIGEA14; arb1; Chibby; PKD2 Interactor,Golgi And Endoplasmic reticulum Associated 1; ARPP-binding protein; Cytosolic leucine-rich protein
Protein chibby homolog 1 is a transcriptional activator and oncoprotein involved in the development of several cancers. The protein encoded by this gene interacts directly with the C-terminal region of beta-catenin, inhibiting oncogenic beta-catenin-mediated transcriptional activation by competing with transcription factors for binding to beta-catenin. Two transcript variants encoding different isoforms have been found for this gene. Inhibits the Wnt/Wingless pathway by binding to beta- catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin-2/PKD2 and possibly of other intracellular proteins. Promotes adipocyte and cardiomyocyte differentiation.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU484Hu01 | Recombinant Chibby Homolog 1 (CBY1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU484Hu01 | Monoclonal Antibody to Chibby Homolog 1 (CBY1) | WB; IHC; ICC; IP. |
| PAU484Hu01 | Polyclonal Antibody to Chibby Homolog 1 (CBY1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU484Hu01 | CLIA Kit for Chibby Homolog 1 (CBY1) | CLIA assay for Antigen Detection |
| ELU484Hu01 | ELISA Kit for Chibby Homolog 1 (CBY1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU484Mu01 | Recombinant Chibby Homolog 1 (CBY1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU484Mu01 | Monoclonal Antibody to Chibby Homolog 1 (CBY1) | WB; IHC; ICC; IP. |
| PAU484Mu01 | Polyclonal Antibody to Chibby Homolog 1 (CBY1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU484Mu01 | CLIA Kit for Chibby Homolog 1 (CBY1) | CLIA assay for Antigen Detection |
| ELU484Mu01 | ELISA Kit for Chibby Homolog 1 (CBY1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU484Ra01 | Recombinant Chibby Homolog 1 (CBY1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU484Ra01 | Monoclonal Antibody to Chibby Homolog 1 (CBY1) | WB; IHC; ICC; IP. |
| PAU484Ra01 | Polyclonal Antibody to Chibby Homolog 1 (CBY1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU484Ra01 | CLIA Kit for Chibby Homolog 1 (CBY1) | CLIA assay for Antigen Detection |
| ELU484Ra01 | ELISA Kit for Chibby Homolog 1 (CBY1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU484Ca01 | Recombinant Chibby Homolog 1 (CBY1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU484Ca01 | Monoclonal Antibody to Chibby Homolog 1 (CBY1) | WB; IHC; ICC; IP. |
| PAU484Ca01 | Polyclonal Antibody to Chibby Homolog 1 (CBY1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU484Ca01 | CLIA Kit for Chibby Homolog 1 (CBY1) | CLIA assay for Antigen Detection |
| ELU484Ca01 | ELISA Kit for Chibby Homolog 1 (CBY1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU484Po01 | Recombinant Chibby Homolog 1 (CBY1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU484Po01 | Monoclonal Antibody to Chibby Homolog 1 (CBY1) | WB; IHC; ICC; IP. |
| PAU484Po01 | Polyclonal Antibody to Chibby Homolog 1 (CBY1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU484Po01 | CLIA Kit for Chibby Homolog 1 (CBY1) | CLIA assay for Antigen Detection |
| ELU484Po01 | ELISA Kit for Chibby Homolog 1 (CBY1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU484Bo01 | Recombinant Chibby Homolog 1 (CBY1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU484Bo01 | Monoclonal Antibody to Chibby Homolog 1 (CBY1) | WB; IHC; ICC; IP. |
| PAU484Bo01 | Polyclonal Antibody to Chibby Homolog 1 (CBY1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU484Bo01 | CLIA Kit for Chibby Homolog 1 (CBY1) | CLIA assay for Antigen Detection |
| ELU484Bo01 | ELISA Kit for Chibby Homolog 1 (CBY1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU484Rb01 | Recombinant Chibby Homolog 1 (CBY1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU484Rb01 | Monoclonal Antibody to Chibby Homolog 1 (CBY1) | WB; IHC; ICC; IP. |
| PAU484Rb01 | Polyclonal Antibody to Chibby Homolog 1 (CBY1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU484Rb01 | CLIA Kit for Chibby Homolog 1 (CBY1) | CLIA assay for Antigen Detection |
| ELU484Rb01 | ELISA Kit for Chibby Homolog 1 (CBY1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU484Mo01 | Recombinant Chibby Homolog 1 (CBY1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU484Mo01 | Monoclonal Antibody to Chibby Homolog 1 (CBY1) | WB; IHC; ICC; IP. |
| PAU484Mo01 | Polyclonal Antibody to Chibby Homolog 1 (CBY1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU484Mo01 | CLIA Kit for Chibby Homolog 1 (CBY1) | CLIA assay for Antigen Detection |
| ELU484Mo01 | ELISA Kit for Chibby Homolog 1 (CBY1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
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