Home
›
Cardiotrophin Like Cytokine Factor 1 (CLCF1)
Cardiotrophin Like Cytokine Factor 1 (CLCF1)
CLC; NR6; BSF3; CISS2; NNT1; Novel Neurotrophin-1; B Cell-Stimulating Factor-3
IL6 family members share similarity in gene structure and have a 4-helix bundle in their protein structure. CLCF1 is closely related to other proteins called cardiotrophin-1 and ciliary neurotrophic factor.
CLCF1 induces tyrosine phosphorylation of the IL-6 receptor common subunit glycoprotein 130 (gp130), leukemia inhibitory factor receptor beta, and the transcription factor STAT3. It has been implicated in the induction of IL-1 (via induction of corticosterone and IL-6) and serum amyloid A, and in B cell hyperplasia. This cytokine is capable of B cell activation via gp130 receptor stimulation.The term "neurotrophin" is commonly used to refer collectively to the four structurally related factors NGF, BDNF, NT-3 and NT-4, while NNT1 bears no structural resemblance to these four proteins.
Organism species: Homo sapiens (Human)
Organism species: Mus musculus (Mouse)
Organism species: Rattus norvegicus (Rat)
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Cardiotrophin Like Cytokine Factor 1 (CLCF1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Cardiotrophin Like Cytokine Factor 1 (CLCF1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Cardiotrophin Like Cytokine Factor 1 (CLCF1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Cardiotrophin Like Cytokine Factor 1 (CLCF1) CLIA assay for Antigen Detection
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Cardiotrophin Like Cytokine Factor 1 (CLCF1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Cardiotrophin Like Cytokine Factor 1 (CLCF1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Cardiotrophin Like Cytokine Factor 1 (CLCF1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Cardiotrophin Like Cytokine Factor 1 (CLCF1) CLIA assay for Antigen Detection
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Cardiotrophin Like Cytokine Factor 1 (CLCF1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Cardiotrophin Like Cytokine Factor 1 (CLCF1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Cardiotrophin Like Cytokine Factor 1 (CLCF1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Cardiotrophin Like Cytokine Factor 1 (CLCF1) CLIA assay for Antigen Detection
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Cardiotrophin Like Cytokine Factor 1 (CLCF1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Cardiotrophin Like Cytokine Factor 1 (CLCF1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Cardiotrophin Like Cytokine Factor 1 (CLCF1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Cardiotrophin Like Cytokine Factor 1 (CLCF1) CLIA assay for Antigen Detection
Organism species: Chicken (Gallus)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Cardiotrophin Like Cytokine Factor 1 (CLCF1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Cardiotrophin Like Cytokine Factor 1 (CLCF1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Cardiotrophin Like Cytokine Factor 1 (CLCF1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Cardiotrophin Like Cytokine Factor 1 (CLCF1) CLIA assay for Antigen Detection
Organism species: Ovis aries; Ovine (Sheep)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Cardiotrophin Like Cytokine Factor 1 (CLCF1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Cardiotrophin Like Cytokine Factor 1 (CLCF1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Cardiotrophin Like Cytokine Factor 1 (CLCF1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Cardiotrophin Like Cytokine Factor 1 (CLCF1) CLIA assay for Antigen Detection
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Cardiotrophin Like Cytokine Factor 1 (CLCF1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Cardiotrophin Like Cytokine Factor 1 (CLCF1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Cardiotrophin Like Cytokine Factor 1 (CLCF1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Cardiotrophin Like Cytokine Factor 1 (CLCF1) CLIA assay for Antigen Detection
Organism species: Cavia (Guinea pig )
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Cardiotrophin Like Cytokine Factor 1 (CLCF1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Cardiotrophin Like Cytokine Factor 1 (CLCF1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Cardiotrophin Like Cytokine Factor 1 (CLCF1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Cardiotrophin Like Cytokine Factor 1 (CLCF1) CLIA assay for Antigen Detection
Organism species: Equus caballus; Equine (Horse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Cardiotrophin Like Cytokine Factor 1 (CLCF1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Cardiotrophin Like Cytokine Factor 1 (CLCF1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Cardiotrophin Like Cytokine Factor 1 (CLCF1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Cardiotrophin Like Cytokine Factor 1 (CLCF1) CLIA assay for Antigen Detection
Organism species: Capra hircus; Caprine (Goat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Cardiotrophin Like Cytokine Factor 1 (CLCF1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Cardiotrophin Like Cytokine Factor 1 (CLCF1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Cardiotrophin Like Cytokine Factor 1 (CLCF1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Cardiotrophin Like Cytokine Factor 1 (CLCF1) CLIA assay for Antigen Detection
Organism species: Pan-species (General)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Cardiotrophin Like Cytokine Factor 1 (CLCF1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Cardiotrophin Like Cytokine Factor 1 (CLCF1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Cardiotrophin Like Cytokine Factor 1 (CLCF1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Cardiotrophin Like Cytokine Factor 1 (CLCF1) CLIA assay for Antigen Detection
Reference
"Novel neurotrophin-1/B cell-stimulating factor-3: a cytokine of the IL-6 family." Proc. Natl. Acad. Sci. U.S.A. 96:11458-11463(1999) [PubMed ] [Europe PMC ] [Abstract ]
"Computational EST database analysis identifies a novel member of the neuropoietic cytokine family." Biochem. Biophys. Res. Commun. 262:132-138(1999) [PubMed ] [Europe PMC ] [Abstract ]
"Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed ] [Europe PMC ] [Abstract ]
"Human chromosome 11 DNA sequence and analysis including novel gene identification." Nature 440:497-500(2006) [PubMed ] [Europe PMC ] [Abstract ]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." Genome Res. 14:2121-2127(2004) [PubMed ] [Europe PMC ] [Abstract ]
"Inactivation of cardiotrophin-like cytokine, a second ligand for ciliary neurotrophic factor receptor, leads to cold-induced sweating syndrome in a patient." Proc. Natl. Acad. Sci. U.S.A. 103:10068-10073(2006) [PubMed ] [Europe PMC ] [Abstract ]