Cortistatin (CORT)

CST14; CST17; CST29

SPN	U455
HGNC	2257
MGI	109538
PubMed	11011067
RGD	2383
UniProt	O00230
Wiki	Cortistatin

Cortistatin, also known as CORT, is a neuropeptide with strong structural similarity to somatostatin. It binds to all known somatostatin receptors, and shares many pharmacological and functional properties with somatostatin, including the depression of neuronal activity.

However, it also has many properties distinct from somatostatin, such as induction of slow-wave sleep, apparently by antagonism of the excitatory effects of acetylcholine on the cortex, reduction of locomotor activity, and activation of cation selective currents not responsive to somatostatin.

Organism species: Homo sapiens (Human)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	U455Hu01	Recombinant Cortistatin (CORT)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Cortistatin (CORT)	Bioactivity
Antibodies	MU455Hu22	Monoclonal Antibody to Cortistatin (CORT)	WB; IHC; ICC; IP.
	PU455Hu01	Polyclonal Antibody to Cortistatin (CORT)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Cortistatin (CORT)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Cortistatin (CORT)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Cortistatin (CORT)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Cortistatin (CORT)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Cortistatin (CORT)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Cortistatin (CORT)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Cortistatin (CORT)	CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Cortistatin (CORT)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Cortistatin (CORT)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Cortistatin (CORT)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Cortistatin (CORT)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Cortistatin (CORT)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Cortistatin (CORT)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Cortistatin (CORT)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Cortistatin (CORT)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Cortistatin (CORT)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Cortistatin (CORT)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Cortistatin (CORT)	CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Cortistatin (CORT)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Cortistatin (CORT)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Cortistatin (CORT)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Cortistatin (CORT)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Cortistatin (CORT)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Cortistatin (CORT)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Cortistatin (CORT)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Cortistatin (CORT)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Cortistatin (CORT)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Cortistatin (CORT)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Cortistatin (CORT)	CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Cortistatin (CORT)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Cortistatin (CORT)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Cortistatin (CORT)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Cortistatin (CORT)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Cortistatin (CORT)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Cortistatin (CORT)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Cortistatin (CORT)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Cortistatin (CORT)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Cortistatin (CORT)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Cortistatin (CORT)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Cortistatin (CORT)	CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Cortistatin (CORT)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Cortistatin (CORT)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Cortistatin (CORT)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Cortistatin (CORT)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Cortistatin (CORT)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Cortistatin (CORT)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Cortistatin (CORT)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Cortistatin (CORT)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Cortistatin (CORT)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Cortistatin (CORT)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Cortistatin (CORT)	CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Cortistatin (CORT)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Cortistatin (CORT)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Cortistatin (CORT)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Cortistatin (CORT)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Cortistatin (CORT)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Cortistatin (CORT)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Cortistatin (CORT)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Cortistatin (CORT)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Cortistatin (CORT)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Cortistatin (CORT)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Cortistatin (CORT)	CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Cortistatin (CORT)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Cortistatin (CORT)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Cortistatin (CORT)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Cortistatin (CORT)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Cortistatin (CORT)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Cortistatin (CORT)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Cortistatin (CORT)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Cortistatin (CORT)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Cortistatin (CORT)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Cortistatin (CORT)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Cortistatin (CORT)	CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Cortistatin (CORT)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Cortistatin (CORT)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Cortistatin (CORT)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Cortistatin (CORT)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Cortistatin (CORT)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Cortistatin (CORT)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Cortistatin (CORT)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Cortistatin (CORT)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Cortistatin (CORT)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Cortistatin (CORT)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Cortistatin (CORT)	CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Cortistatin (CORT)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Cortistatin (CORT)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Cortistatin (CORT)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Cortistatin (CORT)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Cortistatin (CORT)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Cortistatin (CORT)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Cortistatin (CORT)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Cortistatin (CORT)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Cortistatin (CORT)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Cortistatin (CORT)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Cortistatin (CORT)	CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Cortistatin (CORT)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Cortistatin (CORT)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Cortistatin (CORT)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Cortistatin (CORT)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Cortistatin (CORT)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Cortistatin (CORT)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Cortistatin (CORT)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Cortistatin (CORT)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Cortistatin (CORT)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Cortistatin (CORT)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Cortistatin (CORT)	CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Cortistatin (CORT)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Cortistatin (CORT)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Cortistatin (CORT)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Cortistatin (CORT)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Cortistatin (CORT)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Cortistatin (CORT)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Cortistatin (CORT)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Cortistatin (CORT)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Cortistatin (CORT)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Cortistatin (CORT)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Cortistatin (CORT)	CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Cortistatin (CORT)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Cortistatin (CORT)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Cortistatin (CORT)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Cortistatin (CORT)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Cortistatin (CORT)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Cortistatin (CORT)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Cortistatin (CORT)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Cortistatin (CORT)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Cortistatin (CORT)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Cortistatin (CORT)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Cortistatin (CORT)	CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Cortistatin (CORT)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Cortistatin (CORT)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Cortistatin (CORT)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Cortistatin (CORT)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Cortistatin (CORT)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Cortistatin (CORT)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Cortistatin (CORT)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Cortistatin (CORT)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Cortistatin (CORT)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Cortistatin (CORT)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Cortistatin (CORT)	CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Cortistatin (CORT)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Cortistatin (CORT)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Cortistatin (CORT)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Cortistatin (CORT)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Cortistatin (CORT)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Cortistatin (CORT)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Cortistatin (CORT)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Cortistatin (CORT)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Cortistatin (CORT)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Cortistatin (CORT)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Cortistatin (CORT)	CLIA assay for Antigen Detection

Reference

"Identification and characterization of a novel human cortistatin-like peptide."
Biochem. Biophys. Res. Commun. 232:157-163(1997) [PubMed] [Europe PMC] [Abstract]

"Cloning, mRNA expression, and chromosomal mapping of mouse and human preprocortistatin."
Genomics 42:499-506(1997) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence and biological annotation of human chromosome 1."
Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]