Collapsin Response Mediator Protein 1 (CRMP1)
DPYSL1; DRP1; Dihydropyrimidinase Like 1; Dihydropyrimidinase-related protein 1; Unc-33-like phosphoprotein 3
Collapsin response mediator protein 1 is a member of a family of cytosolic phosphoproteins expressed exclusively in the nervous system. The encoded protein is thought to be a part of the semaphorin signal transduction pathway implicated in semaphorin-induced growth cone collapse during neural development. Alternative splicing results in multiple transcript variants.
CRMP1 mediates reelin signaling in cortical neuronal migration. Mice deficient in CRMP1 exhibit impaired long-term potentiation and impaired spatial learning and memory.CRMP1 gene overlaps with another gene called EVC.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU444Hu01 | Recombinant Collapsin Response Mediator Protein 1 (CRMP1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU444Hu01 | Monoclonal Antibody to Collapsin Response Mediator Protein 1 (CRMP1) | WB; IHC; ICC; IP. |
| PAU444Hu01 | Polyclonal Antibody to Collapsin Response Mediator Protein 1 (CRMP1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU444Hu01 | CLIA Kit for Collapsin Response Mediator Protein 1 (CRMP1) | CLIA assay for Antigen Detection |
| ELU444Hu01 | ELISA Kit for Collapsin Response Mediator Protein 1 (CRMP1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU444Mu01 | Recombinant Collapsin Response Mediator Protein 1 (CRMP1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU444Mu01 | Monoclonal Antibody to Collapsin Response Mediator Protein 1 (CRMP1) | WB; IHC; ICC; IP. |
| PAU444Mu01 | Polyclonal Antibody to Collapsin Response Mediator Protein 1 (CRMP1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU444Mu01 | CLIA Kit for Collapsin Response Mediator Protein 1 (CRMP1) | CLIA assay for Antigen Detection |
| ELU444Mu01 | ELISA Kit for Collapsin Response Mediator Protein 1 (CRMP1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU444Ra01 | Recombinant Collapsin Response Mediator Protein 1 (CRMP1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU444Ra01 | Monoclonal Antibody to Collapsin Response Mediator Protein 1 (CRMP1) | WB; IHC; ICC; IP. |
| PAU444Ra01 | Polyclonal Antibody to Collapsin Response Mediator Protein 1 (CRMP1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU444Ra01 | CLIA Kit for Collapsin Response Mediator Protein 1 (CRMP1) | CLIA assay for Antigen Detection |
| ELU444Ra01 | ELISA Kit for Collapsin Response Mediator Protein 1 (CRMP1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU444Ca01 | Recombinant Collapsin Response Mediator Protein 1 (CRMP1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU444Ca01 | Monoclonal Antibody to Collapsin Response Mediator Protein 1 (CRMP1) | WB; IHC; ICC; IP. |
| PAU444Ca01 | Polyclonal Antibody to Collapsin Response Mediator Protein 1 (CRMP1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU444Ca01 | CLIA Kit for Collapsin Response Mediator Protein 1 (CRMP1) | CLIA assay for Antigen Detection |
| ELU444Ca01 | ELISA Kit for Collapsin Response Mediator Protein 1 (CRMP1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU444Po01 | Recombinant Collapsin Response Mediator Protein 1 (CRMP1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU444Po01 | Monoclonal Antibody to Collapsin Response Mediator Protein 1 (CRMP1) | WB; IHC; ICC; IP. |
| PAU444Po01 | Polyclonal Antibody to Collapsin Response Mediator Protein 1 (CRMP1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU444Po01 | CLIA Kit for Collapsin Response Mediator Protein 1 (CRMP1) | CLIA assay for Antigen Detection |
| ELU444Po01 | ELISA Kit for Collapsin Response Mediator Protein 1 (CRMP1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU444Bo01 | Recombinant Collapsin Response Mediator Protein 1 (CRMP1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU444Bo01 | Monoclonal Antibody to Collapsin Response Mediator Protein 1 (CRMP1) | WB; IHC; ICC; IP. |
| PAU444Bo01 | Polyclonal Antibody to Collapsin Response Mediator Protein 1 (CRMP1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU444Bo01 | CLIA Kit for Collapsin Response Mediator Protein 1 (CRMP1) | CLIA assay for Antigen Detection |
| ELU444Bo01 | ELISA Kit for Collapsin Response Mediator Protein 1 (CRMP1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU444Rb01 | Recombinant Collapsin Response Mediator Protein 1 (CRMP1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU444Rb01 | Monoclonal Antibody to Collapsin Response Mediator Protein 1 (CRMP1) | WB; IHC; ICC; IP. |
| PAU444Rb01 | Polyclonal Antibody to Collapsin Response Mediator Protein 1 (CRMP1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU444Rb01 | CLIA Kit for Collapsin Response Mediator Protein 1 (CRMP1) | CLIA assay for Antigen Detection |
| ELU444Rb01 | ELISA Kit for Collapsin Response Mediator Protein 1 (CRMP1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU444Mo01 | Recombinant Collapsin Response Mediator Protein 1 (CRMP1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU444Mo01 | Monoclonal Antibody to Collapsin Response Mediator Protein 1 (CRMP1) | WB; IHC; ICC; IP. |
| PAU444Mo01 | Polyclonal Antibody to Collapsin Response Mediator Protein 1 (CRMP1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU444Mo01 | CLIA Kit for Collapsin Response Mediator Protein 1 (CRMP1) | CLIA assay for Antigen Detection |
| ELU444Mo01 | ELISA Kit for Collapsin Response Mediator Protein 1 (CRMP1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"A novel gene family defined by human dihydropyrimidinase and three related proteins with differential tissue distribution."
Gene 180:157-163(1996) [PubMed] [Europe PMC] [Abstract]
"Long form collapsin response mediator protein-1 (LCRMP-1) expression is associated with clinical outcome and lymph node metastasis in non-small cell lung cancer patients."
Lung Cancer 67:93-100(2010) [PubMed] [Europe PMC] [Abstract]
"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Genomic organization and localization of the human CRMP-1 gene."
DNA Res. 5:393-395(1998) [PubMed] [Europe PMC] [Abstract]
"Collapsin-induced growth cone collapse mediated by an intracellular protein related to UNC-33."
Nature 376:509-514(1995) [PubMed] [Europe PMC] [Abstract]
, Submitted (DEC-2008) to UniProtKB
"Brain CRMP forms heterotetramers similar to liver dihydropyrimidinase."
J. Neurochem. 69:2261-2269(1997) [PubMed] [Europe PMC] [Abstract]
"Collapsin response mediator protein-1 and the invasion and metastasis of cancer cells."
J. Natl. Cancer Inst. 93:1392-1400(2001) [PubMed] [Europe PMC] [Abstract]
"From midbody protein-protein interaction network construction to novel regulators in cytokinesis."
J. Proteome Res. 8:4943-4953(2009) [PubMed] [Europe PMC] [Abstract]