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Cytoglobin (CYGB)

HGB; STAP; Stellate Cell Activation-Associated Protein; Histoglobin

SPN U422
HGNC 16505
MGI 2149481
PubMed 11919282
RGD 69415
UniProt Q8WWM9
Wiki Cytoglobin
Cytoglobin is a globin molecule located in the brain and most notably utilised in marine mammals. It is thought to be a method of protection under conditions of hypoxia. The predicted function of cytoglobin is the transfer of oxygen from arterial blood to the brain.
Cytoglobin is a ubiquitously expressed hexacoordinate hemoglobin that may facilitate diffusion of oxygen through tissues, scavenge nitric oxide or other reactive oxygen species, or serve a protective function during oxidative stress (Trent and Hargrove, 2002). CYGB expression can be used as a specific marker with which hepatic stellate cells can be distinguished from portal myofibroblasts in the damaged human liver.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins U422Hu01 Recombinant Cytoglobin (CYGB) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cytoglobin (CYGB) Bioactivity
Antibodies MU422Hu22 Monoclonal Antibody to Cytoglobin (CYGB) WB; IHC; ICC; IP.
PU422Hu01 Polyclonal Antibody to Cytoglobin (CYGB) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cytoglobin (CYGB) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cytoglobin (CYGB) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cytoglobin (CYGB) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cytoglobin (CYGB) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cytoglobin (CYGB) Flow Cytometry;ICC/IF
Assay Kits KEU422Hu ELISA Kit for Cytoglobin (CYGB) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cytoglobin (CYGB) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cytoglobin (CYGB) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cytoglobin (CYGB) Bioactivity
Antibodies NONE Monoclonal Antibody to Cytoglobin (CYGB) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cytoglobin (CYGB) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cytoglobin (CYGB) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cytoglobin (CYGB) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cytoglobin (CYGB) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cytoglobin (CYGB) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cytoglobin (CYGB) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cytoglobin (CYGB) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cytoglobin (CYGB) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins U422Ra01 Recombinant Cytoglobin (CYGB) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cytoglobin (CYGB) Bioactivity
Antibodies MU422Ra21 Monoclonal Antibody to Cytoglobin (CYGB) WB; IHC; ICC; IP.
PU422Ra01 Polyclonal Antibody to Cytoglobin (CYGB) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cytoglobin (CYGB) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cytoglobin (CYGB) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cytoglobin (CYGB) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cytoglobin (CYGB) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cytoglobin (CYGB) Flow Cytometry;ICC/IF
Assay Kits KEU422Ra ELISA Kit for Cytoglobin (CYGB) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cytoglobin (CYGB) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cytoglobin (CYGB) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cytoglobin (CYGB) Bioactivity
Antibodies NONE Monoclonal Antibody to Cytoglobin (CYGB) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cytoglobin (CYGB) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cytoglobin (CYGB) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cytoglobin (CYGB) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cytoglobin (CYGB) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cytoglobin (CYGB) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cytoglobin (CYGB) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cytoglobin (CYGB) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cytoglobin (CYGB) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cytoglobin (CYGB) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cytoglobin (CYGB) Bioactivity
Antibodies NONE Monoclonal Antibody to Cytoglobin (CYGB) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cytoglobin (CYGB) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cytoglobin (CYGB) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cytoglobin (CYGB) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cytoglobin (CYGB) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cytoglobin (CYGB) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cytoglobin (CYGB) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cytoglobin (CYGB) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cytoglobin (CYGB) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cytoglobin (CYGB) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cytoglobin (CYGB) Bioactivity
Antibodies NONE Monoclonal Antibody to Cytoglobin (CYGB) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cytoglobin (CYGB) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cytoglobin (CYGB) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cytoglobin (CYGB) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cytoglobin (CYGB) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cytoglobin (CYGB) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cytoglobin (CYGB) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cytoglobin (CYGB) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cytoglobin (CYGB) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cytoglobin (CYGB) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cytoglobin (CYGB) Bioactivity
Antibodies NONE Monoclonal Antibody to Cytoglobin (CYGB) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cytoglobin (CYGB) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cytoglobin (CYGB) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cytoglobin (CYGB) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cytoglobin (CYGB) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cytoglobin (CYGB) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cytoglobin (CYGB) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cytoglobin (CYGB) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cytoglobin (CYGB) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cytoglobin (CYGB) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cytoglobin (CYGB) Bioactivity
Antibodies NONE Monoclonal Antibody to Cytoglobin (CYGB) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cytoglobin (CYGB) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cytoglobin (CYGB) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cytoglobin (CYGB) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cytoglobin (CYGB) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cytoglobin (CYGB) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cytoglobin (CYGB) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cytoglobin (CYGB) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cytoglobin (CYGB) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cytoglobin (CYGB) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cytoglobin (CYGB) Bioactivity
Antibodies NONE Monoclonal Antibody to Cytoglobin (CYGB) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cytoglobin (CYGB) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cytoglobin (CYGB) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cytoglobin (CYGB) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cytoglobin (CYGB) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cytoglobin (CYGB) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cytoglobin (CYGB) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cytoglobin (CYGB) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cytoglobin (CYGB) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cytoglobin (CYGB) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cytoglobin (CYGB) Bioactivity
Antibodies NONE Monoclonal Antibody to Cytoglobin (CYGB) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cytoglobin (CYGB) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cytoglobin (CYGB) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cytoglobin (CYGB) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cytoglobin (CYGB) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cytoglobin (CYGB) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cytoglobin (CYGB) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cytoglobin (CYGB) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cytoglobin (CYGB) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cytoglobin (CYGB) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cytoglobin (CYGB) Bioactivity
Antibodies NONE Monoclonal Antibody to Cytoglobin (CYGB) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cytoglobin (CYGB) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cytoglobin (CYGB) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cytoglobin (CYGB) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cytoglobin (CYGB) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cytoglobin (CYGB) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cytoglobin (CYGB) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cytoglobin (CYGB) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cytoglobin (CYGB) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cytoglobin (CYGB) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cytoglobin (CYGB) Bioactivity
Antibodies NONE Monoclonal Antibody to Cytoglobin (CYGB) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cytoglobin (CYGB) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cytoglobin (CYGB) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cytoglobin (CYGB) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cytoglobin (CYGB) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cytoglobin (CYGB) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cytoglobin (CYGB) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cytoglobin (CYGB) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cytoglobin (CYGB) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cytoglobin (CYGB) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cytoglobin (CYGB) Bioactivity
Antibodies NONE Monoclonal Antibody to Cytoglobin (CYGB) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cytoglobin (CYGB) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cytoglobin (CYGB) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cytoglobin (CYGB) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cytoglobin (CYGB) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cytoglobin (CYGB) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cytoglobin (CYGB) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cytoglobin (CYGB) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cytoglobin (CYGB) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cytoglobin (CYGB) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cytoglobin (CYGB) Bioactivity
Antibodies NONE Monoclonal Antibody to Cytoglobin (CYGB) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cytoglobin (CYGB) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cytoglobin (CYGB) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cytoglobin (CYGB) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cytoglobin (CYGB) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cytoglobin (CYGB) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cytoglobin (CYGB) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cytoglobin (CYGB) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cytoglobin (CYGB) CLIA assay for Antigen Detection

Reference

"Cytoglobin: a novel globin type ubiquitously expressed in vertebrate tissues."
Mol. Biol. Evol. 19:416-421(2002) [PubMed] [Europe PMC] [Abstract]

"Characterization of human stellate cell activation-associated protein and its expression in human liver."
Biochim. Biophys. Acta 1577:471-475(2002) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"A ubiquitously expressed human hexacoordinate hemoglobin."
J. Biol. Chem. 277:19538-19545(2002) [PubMed] [Europe PMC] [Abstract]

"Mapping protein matrix cavities in human cytoglobin through Xe atom binding."
Biochem. Biophys. Res. Commun. 316:1217-1221(2004) [PubMed] [Europe PMC] [Abstract]

"Crystal structure of cytoglobin: the fourth globin type discovered in man displays heme hexa-coordination."
J. Mol. Biol. 336:917-927(2004) [PubMed] [Europe PMC] [Abstract]

"Structural basis of human cytoglobin for ligand binding."
J. Mol. Biol. 339:873-885(2004) [PubMed] [Europe PMC] [Abstract]

"High-resolution structure of human cytoglobin: identification of extra N-and C-termini and a new dimerization mode."
Acta Crystallogr. D 62:671-677(2006) [PubMed] [Europe PMC] [Abstract]

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