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Dipeptidase 1, Renal (DPEP1)

RDP; MBD1; MDP; Dehydropeptidase-I; Microsomal dipeptidase; Renal dipeptidase

DPEP1 (EC 3.4.13.11) is a kidney membrane enzyme that hydrolyzes a variety of dipeptides and is implicated in renal metabolism of glutathione and its conjugates, e.g., leukotriene D4 (Kozak and Tate, 1982).
DPEP1 is responsible for hydrolysis of the beta-lactam ring of antibiotics, such as penem and carbapenem (Campbell et al., 1984). Earlier, beta-lactamase enzymes were thought to occur only in bacteria, where their probable function was in protecting the organisms against the action of beta-lactam antibiotics. These antibiotics exhibit selective toxicity against bacteria but virtual inertness against many eukaryotic cells (Adachi et al., 1990).

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins U407Hu01 Recombinant Dipeptidase 1, Renal (DPEP1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Dipeptidase 1, Renal (DPEP1) Bioactivity
Antibodies MU407Hu21 Monoclonal Antibody to Dipeptidase 1, Renal (DPEP1) WB; IHC; ICC; IP.
PU407Hu01 Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) Flow Cytometry;ICC/IF
Assay Kits KEU407Hu ELISA Kit for Dipeptidase 1, Renal (DPEP1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Dipeptidase 1, Renal (DPEP1) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Dipeptidase 1, Renal (DPEP1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Dipeptidase 1, Renal (DPEP1) Bioactivity
Antibodies NONE Monoclonal Antibody to Dipeptidase 1, Renal (DPEP1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Dipeptidase 1, Renal (DPEP1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Dipeptidase 1, Renal (DPEP1) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Dipeptidase 1, Renal (DPEP1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Dipeptidase 1, Renal (DPEP1) Bioactivity
Antibodies NONE Monoclonal Antibody to Dipeptidase 1, Renal (DPEP1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Dipeptidase 1, Renal (DPEP1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Dipeptidase 1, Renal (DPEP1) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Dipeptidase 1, Renal (DPEP1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Dipeptidase 1, Renal (DPEP1) Bioactivity
Antibodies NONE Monoclonal Antibody to Dipeptidase 1, Renal (DPEP1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Dipeptidase 1, Renal (DPEP1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Dipeptidase 1, Renal (DPEP1) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Dipeptidase 1, Renal (DPEP1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Dipeptidase 1, Renal (DPEP1) Bioactivity
Antibodies NONE Monoclonal Antibody to Dipeptidase 1, Renal (DPEP1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Dipeptidase 1, Renal (DPEP1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Dipeptidase 1, Renal (DPEP1) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Dipeptidase 1, Renal (DPEP1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Dipeptidase 1, Renal (DPEP1) Bioactivity
Antibodies NONE Monoclonal Antibody to Dipeptidase 1, Renal (DPEP1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Dipeptidase 1, Renal (DPEP1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Dipeptidase 1, Renal (DPEP1) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Dipeptidase 1, Renal (DPEP1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Dipeptidase 1, Renal (DPEP1) Bioactivity
Antibodies NONE Monoclonal Antibody to Dipeptidase 1, Renal (DPEP1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Dipeptidase 1, Renal (DPEP1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Dipeptidase 1, Renal (DPEP1) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Dipeptidase 1, Renal (DPEP1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Dipeptidase 1, Renal (DPEP1) Bioactivity
Antibodies NONE Monoclonal Antibody to Dipeptidase 1, Renal (DPEP1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Dipeptidase 1, Renal (DPEP1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Dipeptidase 1, Renal (DPEP1) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Dipeptidase 1, Renal (DPEP1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Dipeptidase 1, Renal (DPEP1) Bioactivity
Antibodies NONE Monoclonal Antibody to Dipeptidase 1, Renal (DPEP1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Dipeptidase 1, Renal (DPEP1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Dipeptidase 1, Renal (DPEP1) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Dipeptidase 1, Renal (DPEP1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Dipeptidase 1, Renal (DPEP1) Bioactivity
Antibodies NONE Monoclonal Antibody to Dipeptidase 1, Renal (DPEP1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Dipeptidase 1, Renal (DPEP1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Dipeptidase 1, Renal (DPEP1) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Dipeptidase 1, Renal (DPEP1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Dipeptidase 1, Renal (DPEP1) Bioactivity
Antibodies NONE Monoclonal Antibody to Dipeptidase 1, Renal (DPEP1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Dipeptidase 1, Renal (DPEP1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Dipeptidase 1, Renal (DPEP1) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Dipeptidase 1, Renal (DPEP1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Dipeptidase 1, Renal (DPEP1) Bioactivity
Antibodies NONE Monoclonal Antibody to Dipeptidase 1, Renal (DPEP1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Dipeptidase 1, Renal (DPEP1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Dipeptidase 1, Renal (DPEP1) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Dipeptidase 1, Renal (DPEP1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Dipeptidase 1, Renal (DPEP1) Bioactivity
Antibodies NONE Monoclonal Antibody to Dipeptidase 1, Renal (DPEP1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Dipeptidase 1, Renal (DPEP1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Dipeptidase 1, Renal (DPEP1) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Dipeptidase 1, Renal (DPEP1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Dipeptidase 1, Renal (DPEP1) Bioactivity
Antibodies NONE Monoclonal Antibody to Dipeptidase 1, Renal (DPEP1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Dipeptidase 1, Renal (DPEP1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Dipeptidase 1, Renal (DPEP1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Dipeptidase 1, Renal (DPEP1) CLIA assay for Antigen Detection

Reference

"Cloning and structural analysis of genomic DNA for human renal dipeptidase."
Biochim. Biophys. Acta 1172:181-183(1993) [PubMed] [Europe PMC] [Abstract]

"Primary structure of human microsomal dipeptidase deduced from molecular cloning."
J. Biol. Chem. 265:3992-3995(1990) [PubMed] [Europe PMC] [Abstract]

"Gene structural analysis and expression of human renal dipeptidase."
Biotechnol. Prog. 10:134-140(1994) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Characterization of the glycosyl-phosphatidylinositol-anchored human renal dipeptidase reveals that it is more extensively glycosylated than the pig enzyme."
Biochem. J. 265:429-433(1990) [PubMed] [Europe PMC] [Abstract]

"Purification and characterization of human microsomal dipeptidase."
J. Biochem. 105:957-961(1989) [PubMed] [Europe PMC] [Abstract]

"Signal peptide prediction based on analysis of experimentally verified cleavage sites."
Protein Sci. 13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]

"Identification of membrane anchoring site of human renal dipeptidase and construction and expression of a cDNA for its secretory form."
J. Biol. Chem. 265:15341-15345(1990) [PubMed] [Europe PMC] [Abstract]

"Importance of Glu-125 in the catalytic activity of human renal dipeptidase."
Biochim. Biophys. Acta 1163:42-48(1993) [PubMed] [Europe PMC] [Abstract]

"Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
J. Proteome Res. 8:651-661(2009) [PubMed] [Europe PMC] [Abstract]

"Crystal structure of human renal dipeptidase involved in beta-lactam hydrolysis."
J. Mol. Biol. 321:177-184(2002) [PubMed] [Europe PMC] [Abstract]

"The consensus coding sequences of human breast and colorectal cancers."
Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]