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Engulfment And Cell Motility 2 (ELMO2)

CED12; ELMO2; Protein ced-12 homolog A

Engulfment and cell motility protein 2 interacts with the dedicator of cyto-kinesis 1 protein. Similarity to a C. elegans protein suggests that this protein may function in phagocytosis of apoptotic cells and in cell migration. Alternative splicing results in multiple transcript variants encoding the same protein.
Katoh and Negishi (2003) demonstrated that RHO G interacts directly with ELMO2 in a GTP-dependent manner and forms a ternary complex with DOCK180 to induce activation of RAC1. The RHO G-ELMO2-DOCK180 pathway is required for activation of RAC1 and cell spreading mediated by integrin, as well as for neurite outgrowth induced by nerve growth factor.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins U394Hu01 Recombinant Engulfment And Cell Motility 2 (ELMO2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Engulfment And Cell Motility 2 (ELMO2) Bioactivity
Antibodies NONE Monoclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) WB; IHC; ICC; IP.
PU394Hu01 Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Engulfment And Cell Motility 2 (ELMO2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Engulfment And Cell Motility 2 (ELMO2) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Engulfment And Cell Motility 2 (ELMO2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Engulfment And Cell Motility 2 (ELMO2) Bioactivity
Antibodies NONE Monoclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Engulfment And Cell Motility 2 (ELMO2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Engulfment And Cell Motility 2 (ELMO2) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Engulfment And Cell Motility 2 (ELMO2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Engulfment And Cell Motility 2 (ELMO2) Bioactivity
Antibodies NONE Monoclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Engulfment And Cell Motility 2 (ELMO2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Engulfment And Cell Motility 2 (ELMO2) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Engulfment And Cell Motility 2 (ELMO2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Engulfment And Cell Motility 2 (ELMO2) Bioactivity
Antibodies NONE Monoclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Engulfment And Cell Motility 2 (ELMO2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Engulfment And Cell Motility 2 (ELMO2) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Engulfment And Cell Motility 2 (ELMO2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Engulfment And Cell Motility 2 (ELMO2) Bioactivity
Antibodies NONE Monoclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Engulfment And Cell Motility 2 (ELMO2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Engulfment And Cell Motility 2 (ELMO2) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Engulfment And Cell Motility 2 (ELMO2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Engulfment And Cell Motility 2 (ELMO2) Bioactivity
Antibodies NONE Monoclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Engulfment And Cell Motility 2 (ELMO2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Engulfment And Cell Motility 2 (ELMO2) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Engulfment And Cell Motility 2 (ELMO2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Engulfment And Cell Motility 2 (ELMO2) Bioactivity
Antibodies NONE Monoclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Engulfment And Cell Motility 2 (ELMO2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Engulfment And Cell Motility 2 (ELMO2) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Engulfment And Cell Motility 2 (ELMO2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Engulfment And Cell Motility 2 (ELMO2) Bioactivity
Antibodies NONE Monoclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Engulfment And Cell Motility 2 (ELMO2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Engulfment And Cell Motility 2 (ELMO2) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Engulfment And Cell Motility 2 (ELMO2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Engulfment And Cell Motility 2 (ELMO2) Bioactivity
Antibodies NONE Monoclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Engulfment And Cell Motility 2 (ELMO2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Engulfment And Cell Motility 2 (ELMO2) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Engulfment And Cell Motility 2 (ELMO2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Engulfment And Cell Motility 2 (ELMO2) Bioactivity
Antibodies NONE Monoclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Engulfment And Cell Motility 2 (ELMO2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Engulfment And Cell Motility 2 (ELMO2) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Engulfment And Cell Motility 2 (ELMO2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Engulfment And Cell Motility 2 (ELMO2) Bioactivity
Antibodies NONE Monoclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Engulfment And Cell Motility 2 (ELMO2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Engulfment And Cell Motility 2 (ELMO2) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Engulfment And Cell Motility 2 (ELMO2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Engulfment And Cell Motility 2 (ELMO2) Bioactivity
Antibodies NONE Monoclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Engulfment And Cell Motility 2 (ELMO2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Engulfment And Cell Motility 2 (ELMO2) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Engulfment And Cell Motility 2 (ELMO2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Engulfment And Cell Motility 2 (ELMO2) Bioactivity
Antibodies NONE Monoclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Engulfment And Cell Motility 2 (ELMO2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Engulfment And Cell Motility 2 (ELMO2) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Engulfment And Cell Motility 2 (ELMO2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Engulfment And Cell Motility 2 (ELMO2) Bioactivity
Antibodies NONE Monoclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Engulfment And Cell Motility 2 (ELMO2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Engulfment And Cell Motility 2 (ELMO2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Engulfment And Cell Motility 2 (ELMO2) CLIA assay for Antigen Detection

Reference

"CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration."
Cell 107:27-41(2001) [PubMed] [Europe PMC] [Abstract]

"The C. elegans PH domain protein CED-12 regulates cytoskeletal reorganization via a Rho/Rac GTPase signaling pathway."
Dev. Cell 1:477-489(2001) [PubMed] [Europe PMC] [Abstract]

"Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."
DNA Res. 8:85-95(2001) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence and comparative analysis of human chromosome 20."
Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Ephexin4 and EphA2 mediate cell migration through a RhoG-dependent mechanism."
J. Cell Biol. 190:461-477(2010) [PubMed] [Europe PMC] [Abstract]

"Initial characterization of the human central proteome."
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]