Fas Activated Serine/Threonine Kinase (FASTK)
FAST; STK10
Fas-activated serine/threonine kinase is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein.
The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined.This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups protein-serine/threonine kinases.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU377Hu01 | Recombinant Fas Activated Serine/Threonine Kinase (FASTK) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU377Hu01 | Monoclonal Antibody to Fas Activated Serine/Threonine Kinase (FASTK) | WB; IHC; ICC; IP. |
| PAU377Hu01 | Polyclonal Antibody to Fas Activated Serine/Threonine Kinase (FASTK) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU377Hu01 | CLIA Kit for Fas Activated Serine/Threonine Kinase (FASTK) | CLIA assay for Antigen Detection |
| ELU377Hu01 | ELISA Kit for Fas Activated Serine/Threonine Kinase (FASTK) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU377Mu01 | Recombinant Fas Activated Serine/Threonine Kinase (FASTK) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU377Mu01 | Monoclonal Antibody to Fas Activated Serine/Threonine Kinase (FASTK) | WB; IHC; ICC; IP. |
| PAU377Mu01 | Polyclonal Antibody to Fas Activated Serine/Threonine Kinase (FASTK) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU377Mu01 | CLIA Kit for Fas Activated Serine/Threonine Kinase (FASTK) | CLIA assay for Antigen Detection |
| ELU377Mu01 | ELISA Kit for Fas Activated Serine/Threonine Kinase (FASTK) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU377Ra01 | Recombinant Fas Activated Serine/Threonine Kinase (FASTK) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU377Ra01 | Monoclonal Antibody to Fas Activated Serine/Threonine Kinase (FASTK) | WB; IHC; ICC; IP. |
| PAU377Ra01 | Polyclonal Antibody to Fas Activated Serine/Threonine Kinase (FASTK) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU377Ra01 | CLIA Kit for Fas Activated Serine/Threonine Kinase (FASTK) | CLIA assay for Antigen Detection |
| ELU377Ra01 | ELISA Kit for Fas Activated Serine/Threonine Kinase (FASTK) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU377Ca01 | Recombinant Fas Activated Serine/Threonine Kinase (FASTK) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU377Ca01 | Monoclonal Antibody to Fas Activated Serine/Threonine Kinase (FASTK) | WB; IHC; ICC; IP. |
| PAU377Ca01 | Polyclonal Antibody to Fas Activated Serine/Threonine Kinase (FASTK) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU377Ca01 | CLIA Kit for Fas Activated Serine/Threonine Kinase (FASTK) | CLIA assay for Antigen Detection |
| ELU377Ca01 | ELISA Kit for Fas Activated Serine/Threonine Kinase (FASTK) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU377Po01 | Recombinant Fas Activated Serine/Threonine Kinase (FASTK) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU377Po01 | Monoclonal Antibody to Fas Activated Serine/Threonine Kinase (FASTK) | WB; IHC; ICC; IP. |
| PAU377Po01 | Polyclonal Antibody to Fas Activated Serine/Threonine Kinase (FASTK) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU377Po01 | CLIA Kit for Fas Activated Serine/Threonine Kinase (FASTK) | CLIA assay for Antigen Detection |
| ELU377Po01 | ELISA Kit for Fas Activated Serine/Threonine Kinase (FASTK) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU377Bo01 | Recombinant Fas Activated Serine/Threonine Kinase (FASTK) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU377Bo01 | Monoclonal Antibody to Fas Activated Serine/Threonine Kinase (FASTK) | WB; IHC; ICC; IP. |
| PAU377Bo01 | Polyclonal Antibody to Fas Activated Serine/Threonine Kinase (FASTK) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU377Bo01 | CLIA Kit for Fas Activated Serine/Threonine Kinase (FASTK) | CLIA assay for Antigen Detection |
| ELU377Bo01 | ELISA Kit for Fas Activated Serine/Threonine Kinase (FASTK) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU377Rb01 | Recombinant Fas Activated Serine/Threonine Kinase (FASTK) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU377Rb01 | Monoclonal Antibody to Fas Activated Serine/Threonine Kinase (FASTK) | WB; IHC; ICC; IP. |
| PAU377Rb01 | Polyclonal Antibody to Fas Activated Serine/Threonine Kinase (FASTK) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU377Rb01 | CLIA Kit for Fas Activated Serine/Threonine Kinase (FASTK) | CLIA assay for Antigen Detection |
| ELU377Rb01 | ELISA Kit for Fas Activated Serine/Threonine Kinase (FASTK) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU377Mo01 | Recombinant Fas Activated Serine/Threonine Kinase (FASTK) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU377Mo01 | Monoclonal Antibody to Fas Activated Serine/Threonine Kinase (FASTK) | WB; IHC; ICC; IP. |
| PAU377Mo01 | Polyclonal Antibody to Fas Activated Serine/Threonine Kinase (FASTK) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU377Mo01 | CLIA Kit for Fas Activated Serine/Threonine Kinase (FASTK) | CLIA assay for Antigen Detection |
| ELU377Mo01 | ELISA Kit for Fas Activated Serine/Threonine Kinase (FASTK) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Fas-activated serine/threonine kinase (FAST) phosphorylates TIA-1 during Fas-mediated apoptosis."
J. Exp. Med. 182:865-874(1995) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"The DNA sequence of human chromosome 7."
Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Fas-activated serine/threonine kinase (FAST K) synergizes with TIA-1/TIAR proteins to regulate Fas alternative splicing."
J. Biol. Chem. 282:1539-1543(2007) [PubMed] [Europe PMC] [Abstract]
"Patterns of somatic mutation in human cancer genomes."
Nature 446:153-158(2007) [PubMed] [Europe PMC] [Abstract]