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Envoplakin (EVPL)

EVPK; p210; IVL; 210 kDa cornified envelope precursor protein; 210 kDa paraneoplastic pemphigus antigen

Envoplakin is a protein encoded by the EVPL gene. Ruhrberg et al. (1996) described the cDNA sequence of envoplakin, a membrane-associated protein expressed in human stratified squamous epithelia in skin, oral mucosa, esophageal mucosa, and cervical mucosa. They demonstrated that envoplakin is upregulated in the differentiated layers of the epidermis. Envoplakin is homologous to the keratin-binding proteins desmoplakin I and II, bullous pemphigoid antigen-1 (BPAG1), and plectin. Ruhrberg et al. (1996) suggested that EVPL may be a novel desmosome component involved in anchoring keratin filaments to desmosomes in stratified epithelia. They suggested that in human epidermis envoplakin may link desmosomes and keratin filaments to the cornified envelope.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins U300Hu01 Recombinant Envoplakin (EVPL) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Envoplakin (EVPL) Bioactivity
Antibodies MU300Hu22 Monoclonal Antibody to Envoplakin (EVPL) WB; IHC; ICC; IP.
PU300Hu01 Polyclonal Antibody to Envoplakin (EVPL) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Envoplakin (EVPL) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Envoplakin (EVPL) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Envoplakin (EVPL) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Envoplakin (EVPL) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Envoplakin (EVPL) Flow Cytometry;ICC/IF
Assay Kits KEU300Hu ELISA Kit for Envoplakin (EVPL) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Envoplakin (EVPL) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Envoplakin (EVPL) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Envoplakin (EVPL) Bioactivity
Antibodies NONE Monoclonal Antibody to Envoplakin (EVPL) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Envoplakin (EVPL) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Envoplakin (EVPL) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Envoplakin (EVPL) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Envoplakin (EVPL) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Envoplakin (EVPL) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Envoplakin (EVPL) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Envoplakin (EVPL) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Envoplakin (EVPL) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Envoplakin (EVPL) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Envoplakin (EVPL) Bioactivity
Antibodies NONE Monoclonal Antibody to Envoplakin (EVPL) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Envoplakin (EVPL) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Envoplakin (EVPL) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Envoplakin (EVPL) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Envoplakin (EVPL) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Envoplakin (EVPL) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Envoplakin (EVPL) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Envoplakin (EVPL) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Envoplakin (EVPL) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Envoplakin (EVPL) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Envoplakin (EVPL) Bioactivity
Antibodies NONE Monoclonal Antibody to Envoplakin (EVPL) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Envoplakin (EVPL) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Envoplakin (EVPL) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Envoplakin (EVPL) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Envoplakin (EVPL) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Envoplakin (EVPL) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Envoplakin (EVPL) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Envoplakin (EVPL) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Envoplakin (EVPL) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Envoplakin (EVPL) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Envoplakin (EVPL) Bioactivity
Antibodies NONE Monoclonal Antibody to Envoplakin (EVPL) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Envoplakin (EVPL) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Envoplakin (EVPL) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Envoplakin (EVPL) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Envoplakin (EVPL) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Envoplakin (EVPL) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Envoplakin (EVPL) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Envoplakin (EVPL) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Envoplakin (EVPL) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Envoplakin (EVPL) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Envoplakin (EVPL) Bioactivity
Antibodies NONE Monoclonal Antibody to Envoplakin (EVPL) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Envoplakin (EVPL) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Envoplakin (EVPL) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Envoplakin (EVPL) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Envoplakin (EVPL) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Envoplakin (EVPL) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Envoplakin (EVPL) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Envoplakin (EVPL) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Envoplakin (EVPL) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Envoplakin (EVPL) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Envoplakin (EVPL) Bioactivity
Antibodies NONE Monoclonal Antibody to Envoplakin (EVPL) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Envoplakin (EVPL) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Envoplakin (EVPL) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Envoplakin (EVPL) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Envoplakin (EVPL) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Envoplakin (EVPL) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Envoplakin (EVPL) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Envoplakin (EVPL) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Envoplakin (EVPL) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Envoplakin (EVPL) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Envoplakin (EVPL) Bioactivity
Antibodies NONE Monoclonal Antibody to Envoplakin (EVPL) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Envoplakin (EVPL) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Envoplakin (EVPL) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Envoplakin (EVPL) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Envoplakin (EVPL) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Envoplakin (EVPL) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Envoplakin (EVPL) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Envoplakin (EVPL) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Envoplakin (EVPL) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Envoplakin (EVPL) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Envoplakin (EVPL) Bioactivity
Antibodies NONE Monoclonal Antibody to Envoplakin (EVPL) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Envoplakin (EVPL) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Envoplakin (EVPL) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Envoplakin (EVPL) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Envoplakin (EVPL) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Envoplakin (EVPL) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Envoplakin (EVPL) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Envoplakin (EVPL) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Envoplakin (EVPL) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Envoplakin (EVPL) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Envoplakin (EVPL) Bioactivity
Antibodies NONE Monoclonal Antibody to Envoplakin (EVPL) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Envoplakin (EVPL) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Envoplakin (EVPL) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Envoplakin (EVPL) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Envoplakin (EVPL) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Envoplakin (EVPL) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Envoplakin (EVPL) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Envoplakin (EVPL) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Envoplakin (EVPL) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Envoplakin (EVPL) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Envoplakin (EVPL) Bioactivity
Antibodies NONE Monoclonal Antibody to Envoplakin (EVPL) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Envoplakin (EVPL) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Envoplakin (EVPL) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Envoplakin (EVPL) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Envoplakin (EVPL) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Envoplakin (EVPL) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Envoplakin (EVPL) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Envoplakin (EVPL) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Envoplakin (EVPL) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Envoplakin (EVPL) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Envoplakin (EVPL) Bioactivity
Antibodies NONE Monoclonal Antibody to Envoplakin (EVPL) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Envoplakin (EVPL) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Envoplakin (EVPL) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Envoplakin (EVPL) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Envoplakin (EVPL) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Envoplakin (EVPL) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Envoplakin (EVPL) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Envoplakin (EVPL) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Envoplakin (EVPL) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Envoplakin (EVPL) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Envoplakin (EVPL) Bioactivity
Antibodies NONE Monoclonal Antibody to Envoplakin (EVPL) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Envoplakin (EVPL) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Envoplakin (EVPL) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Envoplakin (EVPL) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Envoplakin (EVPL) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Envoplakin (EVPL) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Envoplakin (EVPL) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Envoplakin (EVPL) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Envoplakin (EVPL) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Envoplakin (EVPL) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Envoplakin (EVPL) Bioactivity
Antibodies NONE Monoclonal Antibody to Envoplakin (EVPL) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Envoplakin (EVPL) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Envoplakin (EVPL) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Envoplakin (EVPL) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Envoplakin (EVPL) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Envoplakin (EVPL) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Envoplakin (EVPL) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Envoplakin (EVPL) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Envoplakin (EVPL) CLIA assay for Antigen Detection

Reference

"Envoplakin, a novel precursor of the cornified envelope that has homology to desmoplakin."
J. Cell Biol. 134:715-729(1996) [PubMed] [Europe PMC] [Abstract]

"Envoplakin, a possible candidate gene for focal NEPPK/esophageal cancer (TOC): the integration of genetic and physical maps of the TOC region on 17q25."
Genomics 59:234-242(1999) [PubMed] [Europe PMC] [Abstract]

"DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage."
Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Ceramides are bound to structural proteins of the human foreskin epidermal cornified cell envelope."
J. Biol. Chem. 273:17763-17770(1998) [PubMed] [Europe PMC] [Abstract]

"Tryptic digestion of ubiquitin standards reveals an improved strategy for identifying ubiquitinated proteins by mass spectrometry."
Proteomics 7:868-874(2007) [PubMed] [Europe PMC] [Abstract]

"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]