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Ureidopropionase Beta (UPb1)

UP-B1; BUP1; Beta-alanine synthase; N-carbamoyl-beta-alanine amidohydrolase

The BUP1 open reading frame of 1,152 bp corresponds to a protein of 384 amino acids with a calculated molecular mass of 43 kD, surrounded by a 5-prime untranslated region of 61 nucleotides and a 3-prime untranslated region of 277 nucleotides. The protein shows 84% identity with the translation product of the rat beta-ureidopropionase cDNA.
Expression of the human cDNA in Escherichia coli and eukaryotic COS-7 cells revealed a very high beta-ureidopropionase enzymatic activity, thus confirming the identity of the cDNA. Human EST libraries from brain, liver, kidney, and heart contained partial beta-ureidopropionase cDNAs, suggesting expression in these tissues, as seen in the rat.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins U263Hu01 Recombinant Ureidopropionase Beta (UPb1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ureidopropionase Beta (UPb1) Bioactivity
Antibodies NONE Monoclonal Antibody to Ureidopropionase Beta (UPb1) WB; IHC; ICC; IP.
PU263Hu01 Polyclonal Antibody to Ureidopropionase Beta (UPb1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ureidopropionase Beta (UPb1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ureidopropionase Beta (UPb1) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins U263Mu01 Recombinant Ureidopropionase Beta (UPb1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ureidopropionase Beta (UPb1) Bioactivity
Antibodies NONE Monoclonal Antibody to Ureidopropionase Beta (UPb1) WB; IHC; ICC; IP.
PU263Mu01 Polyclonal Antibody to Ureidopropionase Beta (UPb1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ureidopropionase Beta (UPb1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ureidopropionase Beta (UPb1) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ureidopropionase Beta (UPb1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ureidopropionase Beta (UPb1) Bioactivity
Antibodies NONE Monoclonal Antibody to Ureidopropionase Beta (UPb1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ureidopropionase Beta (UPb1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ureidopropionase Beta (UPb1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ureidopropionase Beta (UPb1) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ureidopropionase Beta (UPb1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ureidopropionase Beta (UPb1) Bioactivity
Antibodies NONE Monoclonal Antibody to Ureidopropionase Beta (UPb1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ureidopropionase Beta (UPb1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ureidopropionase Beta (UPb1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ureidopropionase Beta (UPb1) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ureidopropionase Beta (UPb1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ureidopropionase Beta (UPb1) Bioactivity
Antibodies NONE Monoclonal Antibody to Ureidopropionase Beta (UPb1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ureidopropionase Beta (UPb1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ureidopropionase Beta (UPb1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ureidopropionase Beta (UPb1) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ureidopropionase Beta (UPb1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ureidopropionase Beta (UPb1) Bioactivity
Antibodies NONE Monoclonal Antibody to Ureidopropionase Beta (UPb1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ureidopropionase Beta (UPb1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ureidopropionase Beta (UPb1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ureidopropionase Beta (UPb1) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ureidopropionase Beta (UPb1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ureidopropionase Beta (UPb1) Bioactivity
Antibodies NONE Monoclonal Antibody to Ureidopropionase Beta (UPb1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ureidopropionase Beta (UPb1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ureidopropionase Beta (UPb1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ureidopropionase Beta (UPb1) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ureidopropionase Beta (UPb1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ureidopropionase Beta (UPb1) Bioactivity
Antibodies NONE Monoclonal Antibody to Ureidopropionase Beta (UPb1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ureidopropionase Beta (UPb1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ureidopropionase Beta (UPb1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ureidopropionase Beta (UPb1) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ureidopropionase Beta (UPb1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ureidopropionase Beta (UPb1) Bioactivity
Antibodies NONE Monoclonal Antibody to Ureidopropionase Beta (UPb1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ureidopropionase Beta (UPb1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ureidopropionase Beta (UPb1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ureidopropionase Beta (UPb1) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ureidopropionase Beta (UPb1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ureidopropionase Beta (UPb1) Bioactivity
Antibodies NONE Monoclonal Antibody to Ureidopropionase Beta (UPb1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ureidopropionase Beta (UPb1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ureidopropionase Beta (UPb1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ureidopropionase Beta (UPb1) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ureidopropionase Beta (UPb1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ureidopropionase Beta (UPb1) Bioactivity
Antibodies NONE Monoclonal Antibody to Ureidopropionase Beta (UPb1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ureidopropionase Beta (UPb1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ureidopropionase Beta (UPb1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ureidopropionase Beta (UPb1) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ureidopropionase Beta (UPb1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ureidopropionase Beta (UPb1) Bioactivity
Antibodies NONE Monoclonal Antibody to Ureidopropionase Beta (UPb1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ureidopropionase Beta (UPb1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ureidopropionase Beta (UPb1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ureidopropionase Beta (UPb1) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ureidopropionase Beta (UPb1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ureidopropionase Beta (UPb1) Bioactivity
Antibodies NONE Monoclonal Antibody to Ureidopropionase Beta (UPb1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ureidopropionase Beta (UPb1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ureidopropionase Beta (UPb1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ureidopropionase Beta (UPb1) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ureidopropionase Beta (UPb1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ureidopropionase Beta (UPb1) Bioactivity
Antibodies NONE Monoclonal Antibody to Ureidopropionase Beta (UPb1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ureidopropionase Beta (UPb1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ureidopropionase Beta (UPb1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ureidopropionase Beta (UPb1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ureidopropionase Beta (UPb1) CLIA assay for Antigen Detection

Reference

"cDNA cloning, genomic structure and chromosomal localization of the human BUP-1 gene encoding beta-ureidopropionase."
Biochim. Biophys. Acta 1447:251-257(1999) [PubMed] [Europe PMC] [Abstract]

"Expression and properties of human liver beta-ureidopropionase."
J. Nutr. Sci. Vitaminol. 47:132-138(2001) [PubMed] [Europe PMC] [Abstract]

"A genome annotation-driven approach to cloning the human ORFeome."
Genome Biol. 5:R84.1-R84.11(2004) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]

"Beta-ureidopropionase deficiency: an inborn error of pyrimidine degradation associated with neurological abnormalities."
Hum. Mol. Genet. 13:2793-2801(2004) [PubMed] [Europe PMC] [Abstract]