Xanthine dehydrogenase belongs to the group of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines. The enzyme is a homodimer. Xanthine dehydrogenase can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification.
The three substrates of this enzyme are xanthine, NAD+, and H2O, whereas its three products are urate, NADH, and H+.This enzyme belongs to the family of oxidoreductases, to be specific, those acting on CH or CH2 group with NAD+ or NADP+ as acceptor.Defects in xanthine dehydrogenase cause xanthinuria, may contribute to adult respiratory stress syndrome, and may potentiate influenza infection through an oxygen metabolite-dependent mechanism.
Monoclonal Antibody to Xanthine Dehydrogenase (XDH)
WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Xanthine Dehydrogenase (XDH)
WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Xanthine Dehydrogenase (XDH)
ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Xanthine Dehydrogenase (XDH)
IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Xanthine Dehydrogenase (XDH)
Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Xanthine Dehydrogenase (XDH)
Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Xanthine Dehydrogenase (XDH)
Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Xanthine Dehydrogenase (XDH)
Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Xanthine Dehydrogenase (XDH)
CLIA assay for Antigen Detection
Organism species: Chicken (Gallus)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Xanthine Dehydrogenase (XDH)
Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Xanthine Dehydrogenase (XDH)
Bioactivity
Antibodies
NONE
Monoclonal Antibody to Xanthine Dehydrogenase (XDH)
WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Xanthine Dehydrogenase (XDH)
WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Xanthine Dehydrogenase (XDH)
ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Xanthine Dehydrogenase (XDH)
IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Xanthine Dehydrogenase (XDH)
Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Xanthine Dehydrogenase (XDH)
Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Xanthine Dehydrogenase (XDH)
Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Xanthine Dehydrogenase (XDH)
Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Xanthine Dehydrogenase (XDH)
CLIA assay for Antigen Detection
Organism species: Ovis aries; Ovine (Sheep)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Xanthine Dehydrogenase (XDH)
Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Xanthine Dehydrogenase (XDH)
Bioactivity
Antibodies
NONE
Monoclonal Antibody to Xanthine Dehydrogenase (XDH)
WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Xanthine Dehydrogenase (XDH)
WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Xanthine Dehydrogenase (XDH)
ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Xanthine Dehydrogenase (XDH)
IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Xanthine Dehydrogenase (XDH)
Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Xanthine Dehydrogenase (XDH)
Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Xanthine Dehydrogenase (XDH)
Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Xanthine Dehydrogenase (XDH)
Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Xanthine Dehydrogenase (XDH)
CLIA assay for Antigen Detection
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Xanthine Dehydrogenase (XDH)
Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Xanthine Dehydrogenase (XDH)
Bioactivity
Antibodies
NONE
Monoclonal Antibody to Xanthine Dehydrogenase (XDH)
WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Xanthine Dehydrogenase (XDH)
WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Xanthine Dehydrogenase (XDH)
ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Xanthine Dehydrogenase (XDH)
IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Xanthine Dehydrogenase (XDH)
Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Xanthine Dehydrogenase (XDH)
Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Xanthine Dehydrogenase (XDH)
Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Xanthine Dehydrogenase (XDH)
Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Xanthine Dehydrogenase (XDH)
CLIA assay for Antigen Detection
Organism species: Cavia (Guinea pig )
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Xanthine Dehydrogenase (XDH)
Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Xanthine Dehydrogenase (XDH)
Bioactivity
Antibodies
NONE
Monoclonal Antibody to Xanthine Dehydrogenase (XDH)
WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Xanthine Dehydrogenase (XDH)
WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Xanthine Dehydrogenase (XDH)
ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Xanthine Dehydrogenase (XDH)
IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Xanthine Dehydrogenase (XDH)
Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Xanthine Dehydrogenase (XDH)
Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Xanthine Dehydrogenase (XDH)
Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Xanthine Dehydrogenase (XDH)
Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Xanthine Dehydrogenase (XDH)
CLIA assay for Antigen Detection
Organism species: Equus caballus; Equine (Horse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Xanthine Dehydrogenase (XDH)
Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Xanthine Dehydrogenase (XDH)
Bioactivity
Antibodies
NONE
Monoclonal Antibody to Xanthine Dehydrogenase (XDH)
WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Xanthine Dehydrogenase (XDH)
WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Xanthine Dehydrogenase (XDH)
ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Xanthine Dehydrogenase (XDH)
IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Xanthine Dehydrogenase (XDH)
Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Xanthine Dehydrogenase (XDH)
Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Xanthine Dehydrogenase (XDH)
Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Xanthine Dehydrogenase (XDH)
Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Xanthine Dehydrogenase (XDH)
CLIA assay for Antigen Detection
Organism species: Capra hircus; Caprine (Goat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Xanthine Dehydrogenase (XDH)
Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Xanthine Dehydrogenase (XDH)
Bioactivity
Antibodies
NONE
Monoclonal Antibody to Xanthine Dehydrogenase (XDH)
WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Xanthine Dehydrogenase (XDH)
WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Xanthine Dehydrogenase (XDH)
ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Xanthine Dehydrogenase (XDH)
IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Xanthine Dehydrogenase (XDH)
Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Xanthine Dehydrogenase (XDH)
Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Xanthine Dehydrogenase (XDH)
Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Xanthine Dehydrogenase (XDH)
Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Xanthine Dehydrogenase (XDH)
CLIA assay for Antigen Detection
Organism species: Pan-species (General)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Xanthine Dehydrogenase (XDH)
Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Xanthine Dehydrogenase (XDH)
Bioactivity
Antibodies
NONE
Monoclonal Antibody to Xanthine Dehydrogenase (XDH)
WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Xanthine Dehydrogenase (XDH)
WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Xanthine Dehydrogenase (XDH)
ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Xanthine Dehydrogenase (XDH)
IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Xanthine Dehydrogenase (XDH)
Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Xanthine Dehydrogenase (XDH)
Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Xanthine Dehydrogenase (XDH)
Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Xanthine Dehydrogenase (XDH)
Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Xanthine Dehydrogenase (XDH)
CLIA assay for Antigen Detection
Reference
"Cloning of the cDNA encoding human xanthine dehydrogenase (oxidase): structural analysis of the protein and chromosomal location of the gene." Gene 133:279-284(1993) [PubMed] [Europe PMC] [Abstract]
"Human xanthine oxidase changes its substrate specificity to aldehyde oxidase type upon mutation of amino acid residues in the active site: roles of active site residues in binding and activation of purine substrate." J. Biochem. 141:513-524(2007) [PubMed] [Europe PMC] [Abstract]
"Human milk xanthine dehydrogenase is incompletely converted to the oxidase form in the absence of proteolysis. A structural explanation." Submitted (FEB-2009) to the PDB data bank