Call Now

Neuroplastin (NPTN)

SDR1; GP55; GP65; SDFR1; np55; np65; Stromal Cell Derived Factor Receptor 1

Neuroplastin is a type I transmembrane protein belonging to the Ig superfamily. The protein is believed to be involved in cell-cell interactions or cell-substrate interactions. The alpha and beta transcripts show differential localization within the brain.
The deduced mature Gp55 and Gp65 proteins contain 253 and 365 amino acid residues with calculated molecular masses of 28.8 and 41.4 kD, respectively. Both species contain a single putative membrane spanning domain, and Gp55 has 2 extracellular Ig domains whereas Gp65 has 3 extracellular Ig domains. Gp55 shares similarity with basigin Ig domain proteins. Immunocytochemical studies localized Gp55 and Gp65 to the cell membrane in HEK293 cells.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU186Hu01 Recombinant Neuroplastin (NPTN) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU186Hu01 Monoclonal Antibody to Neuroplastin (NPTN) WB; IHC; ICC; IP.
PAU186Hu01 Polyclonal Antibody to Neuroplastin (NPTN) WB; IHC; ICC; IF.
Assay Kits CLU186Hu01 CLIA Kit for Neuroplastin (NPTN) CLIA assay for Antigen Detection
ELU186Hu01 ELISA Kit for Neuroplastin (NPTN) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU186Mu01 Recombinant Neuroplastin (NPTN) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU186Mu01 Monoclonal Antibody to Neuroplastin (NPTN) WB; IHC; ICC; IP.
PAU186Mu01 Polyclonal Antibody to Neuroplastin (NPTN) WB; IHC; ICC; IF.
Assay Kits CLU186Mu01 CLIA Kit for Neuroplastin (NPTN) CLIA assay for Antigen Detection
ELU186Mu01 ELISA Kit for Neuroplastin (NPTN) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU186Ra01 Recombinant Neuroplastin (NPTN) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU186Ra01 Monoclonal Antibody to Neuroplastin (NPTN) WB; IHC; ICC; IP.
PAU186Ra01 Polyclonal Antibody to Neuroplastin (NPTN) WB; IHC; ICC; IF.
Assay Kits CLU186Ra01 CLIA Kit for Neuroplastin (NPTN) CLIA assay for Antigen Detection
ELU186Ra01 ELISA Kit for Neuroplastin (NPTN) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU186Ca01 Recombinant Neuroplastin (NPTN) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU186Ca01 Monoclonal Antibody to Neuroplastin (NPTN) WB; IHC; ICC; IP.
PAU186Ca01 Polyclonal Antibody to Neuroplastin (NPTN) WB; IHC; ICC; IF.
Assay Kits CLU186Ca01 CLIA Kit for Neuroplastin (NPTN) CLIA assay for Antigen Detection
ELU186Ca01 ELISA Kit for Neuroplastin (NPTN) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU186Po01 Recombinant Neuroplastin (NPTN) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU186Po01 Monoclonal Antibody to Neuroplastin (NPTN) WB; IHC; ICC; IP.
PAU186Po01 Polyclonal Antibody to Neuroplastin (NPTN) WB; IHC; ICC; IF.
Assay Kits CLU186Po01 CLIA Kit for Neuroplastin (NPTN) CLIA assay for Antigen Detection
ELU186Po01 ELISA Kit for Neuroplastin (NPTN) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU186Bo01 Recombinant Neuroplastin (NPTN) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU186Bo01 Monoclonal Antibody to Neuroplastin (NPTN) WB; IHC; ICC; IP.
PAU186Bo01 Polyclonal Antibody to Neuroplastin (NPTN) WB; IHC; ICC; IF.
Assay Kits CLU186Bo01 CLIA Kit for Neuroplastin (NPTN) CLIA assay for Antigen Detection
ELU186Bo01 ELISA Kit for Neuroplastin (NPTN) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU186Rb01 Recombinant Neuroplastin (NPTN) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU186Rb01 Monoclonal Antibody to Neuroplastin (NPTN) WB; IHC; ICC; IP.
PAU186Rb01 Polyclonal Antibody to Neuroplastin (NPTN) WB; IHC; ICC; IF.
Assay Kits CLU186Rb01 CLIA Kit for Neuroplastin (NPTN) CLIA assay for Antigen Detection
ELU186Rb01 ELISA Kit for Neuroplastin (NPTN) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU186Mo01 Recombinant Neuroplastin (NPTN) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU186Mo01 Monoclonal Antibody to Neuroplastin (NPTN) WB; IHC; ICC; IP.
PAU186Mo01 Polyclonal Antibody to Neuroplastin (NPTN) WB; IHC; ICC; IF.
Assay Kits CLU186Mo01 CLIA Kit for Neuroplastin (NPTN) CLIA assay for Antigen Detection
ELU186Mo01 ELISA Kit for Neuroplastin (NPTN) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"Isoform specific expression of the SDR-1 protein, alpha and beta in subregions of adult rodent brain."
Biomed. Res. 20:43-49(1999)

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Signal peptide prediction based on analysis of experimentally verified cleavage sites."
Protein Sci. 13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]

"The immunolocalization of the synaptic glycoprotein neuroplastin differs substantially between the human and the rodent brain."
Brain Res. 1134:107-112(2007) [PubMed] [Europe PMC] [Abstract]

"Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
J. Proteome Res. 8:651-661(2009) [PubMed] [Europe PMC] [Abstract]

"Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins."
Nat. Biotechnol. 27:378-386(2009) [PubMed] [Europe PMC] [Abstract]

"Initial characterization of the human central proteome."
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]