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Opticin (OPTC)
Opticin (OPTC)
OPT; Oculoglycan
Opticin belongs to class III of the small leucine-rich repeat protein (SLRP) family. Members of this family are typically associated with the extracellular matrix. Opticin is present in significant quantities in the vitreous of the eye and also localizes to the cornea, iris, ciliary body, optic nerve, choroid, retina, and fetal liver.
Opticin may noncovalently bind collagen fibrils and regulate fibril morphology, spacing, and organization. The opticin gene is mapped to a region of chromosome 1 that is associated with the inherited eye diseases age-related macular degeneration (AMD) and posterior column ataxia with retinosa pigmentosa (AXPC1).
Organism species: Homo sapiens (Human)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
U161Hu01
Recombinant Opticin (OPTC) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Opticin (OPTC) Bioactivity
Antibodies
MU161Hu22
Monoclonal Antibody to Opticin (OPTC) WB; IHC; ICC; IP.
PU161Hu01
Polyclonal Antibody to Opticin (OPTC) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Opticin (OPTC) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Opticin (OPTC) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Opticin (OPTC) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Opticin (OPTC) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Opticin (OPTC) Flow Cytometry;ICC/IF
Assay Kits
KEU161Hu
ELISA Kit for Opticin (OPTC) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Opticin (OPTC) CLIA assay for Antigen Detection
Organism species: Mus musculus (Mouse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Opticin (OPTC) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Opticin (OPTC) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Opticin (OPTC) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Opticin (OPTC) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Opticin (OPTC) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Opticin (OPTC) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Opticin (OPTC) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Opticin (OPTC) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Opticin (OPTC) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Opticin (OPTC) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Opticin (OPTC) CLIA assay for Antigen Detection
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Opticin (OPTC) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Opticin (OPTC) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Opticin (OPTC) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Opticin (OPTC) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Opticin (OPTC) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Opticin (OPTC) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Opticin (OPTC) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Opticin (OPTC) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Opticin (OPTC) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Opticin (OPTC) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Opticin (OPTC) CLIA assay for Antigen Detection
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Opticin (OPTC) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Opticin (OPTC) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Opticin (OPTC) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Opticin (OPTC) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Opticin (OPTC) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Opticin (OPTC) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Opticin (OPTC) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Opticin (OPTC) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Opticin (OPTC) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Opticin (OPTC) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Opticin (OPTC) CLIA assay for Antigen Detection
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Opticin (OPTC) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Opticin (OPTC) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Opticin (OPTC) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Opticin (OPTC) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Opticin (OPTC) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Opticin (OPTC) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Opticin (OPTC) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Opticin (OPTC) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Opticin (OPTC) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Opticin (OPTC) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Opticin (OPTC) CLIA assay for Antigen Detection
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Opticin (OPTC) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Opticin (OPTC) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Opticin (OPTC) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Opticin (OPTC) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Opticin (OPTC) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Opticin (OPTC) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Opticin (OPTC) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Opticin (OPTC) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Opticin (OPTC) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Opticin (OPTC) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Opticin (OPTC) CLIA assay for Antigen Detection
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Opticin (OPTC) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Opticin (OPTC) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Opticin (OPTC) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Opticin (OPTC) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Opticin (OPTC) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Opticin (OPTC) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Opticin (OPTC) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Opticin (OPTC) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Opticin (OPTC) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Opticin (OPTC) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Opticin (OPTC) CLIA assay for Antigen Detection
Organism species: Chicken (Gallus)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Opticin (OPTC) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Opticin (OPTC) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Opticin (OPTC) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Opticin (OPTC) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Opticin (OPTC) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Opticin (OPTC) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Opticin (OPTC) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Opticin (OPTC) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Opticin (OPTC) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Opticin (OPTC) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Opticin (OPTC) CLIA assay for Antigen Detection
Organism species: Ovis aries; Ovine (Sheep)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Opticin (OPTC) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Opticin (OPTC) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Opticin (OPTC) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Opticin (OPTC) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Opticin (OPTC) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Opticin (OPTC) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Opticin (OPTC) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Opticin (OPTC) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Opticin (OPTC) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Opticin (OPTC) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Opticin (OPTC) CLIA assay for Antigen Detection
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Opticin (OPTC) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Opticin (OPTC) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Opticin (OPTC) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Opticin (OPTC) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Opticin (OPTC) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Opticin (OPTC) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Opticin (OPTC) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Opticin (OPTC) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Opticin (OPTC) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Opticin (OPTC) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Opticin (OPTC) CLIA assay for Antigen Detection
Organism species: Cavia (Guinea pig )
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Opticin (OPTC) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Opticin (OPTC) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Opticin (OPTC) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Opticin (OPTC) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Opticin (OPTC) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Opticin (OPTC) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Opticin (OPTC) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Opticin (OPTC) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Opticin (OPTC) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Opticin (OPTC) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Opticin (OPTC) CLIA assay for Antigen Detection
Organism species: Equus caballus; Equine (Horse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Opticin (OPTC) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Opticin (OPTC) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Opticin (OPTC) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Opticin (OPTC) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Opticin (OPTC) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Opticin (OPTC) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Opticin (OPTC) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Opticin (OPTC) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Opticin (OPTC) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Opticin (OPTC) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Opticin (OPTC) CLIA assay for Antigen Detection
Organism species: Capra hircus; Caprine (Goat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Opticin (OPTC) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Opticin (OPTC) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Opticin (OPTC) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Opticin (OPTC) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Opticin (OPTC) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Opticin (OPTC) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Opticin (OPTC) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Opticin (OPTC) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Opticin (OPTC) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Opticin (OPTC) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Opticin (OPTC) CLIA assay for Antigen Detection
Organism species: Pan-species (General)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Opticin (OPTC) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Opticin (OPTC) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Opticin (OPTC) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Opticin (OPTC) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Opticin (OPTC) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Opticin (OPTC) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Opticin (OPTC) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Opticin (OPTC) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Opticin (OPTC) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Opticin (OPTC) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Opticin (OPTC) CLIA assay for Antigen Detection
Reference
"Identification in vitreous and molecular cloning of opticin, a novel member of the family of leucine-rich repeat proteins of the extracellular matrix." J. Biol. Chem. 275:2123-2129(2000) [PubMed ] [Europe PMC ] [Abstract ]
"Cloning, modeling, and chromosomal localization for a small leucine-rich repeat proteoglycan (SLRP) family member expressed in human eye." PubMed ] [Europe PMC ] [Abstract ]
"Isolation of a novel iris-specific and leucine-rich repeat protein (oculoglycan) using differential selection." PubMed ] [Europe PMC ] [Abstract ]
"Protein localization in the human eye and genetic screen of opticin." Hum. Mol. Genet. 11:1333-1342(2002) [PubMed ] [Europe PMC ] [Abstract ]
"The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed ] [Europe PMC ] [Abstract ]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." Genome Res. 14:2121-2127(2004) [PubMed ] [Europe PMC ] [Abstract ]
"Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry." J. Proteome Res. 4:2070-2080(2005) [PubMed ] [Europe PMC ] [Abstract ]
