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Pantothenate Kinase 1 (PANK1)
Pantothenate Kinase 1 (PANK1)
PANK; PANK1a; PANK1b; hPanK1; Pantothenic acid kinase 1
Pantothenate kinase 1 is a protein belonging to the pantothenate kinase family. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by CoA. Alternative splicing has been observed at this locus and three variants, each encoding a distinct isoform, have been identified.
Pantothenate kinase1 is expressed at high levels in brain, heart, kidney, liver, skeletal muscle and testis. Isoform 2 is detected at much lower levels in kidney, liver, brain and testis and is not detected in heart or skeletal muscle.
Organism species: Homo sapiens (Human)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Pantothenate Kinase 1 (PANK1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Pantothenate Kinase 1 (PANK1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Pantothenate Kinase 1 (PANK1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Pantothenate Kinase 1 (PANK1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Pantothenate Kinase 1 (PANK1) CLIA assay for Antigen Detection
Organism species: Mus musculus (Mouse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
U143Mu01
Recombinant Pantothenate Kinase 1 (PANK1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Pantothenate Kinase 1 (PANK1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Pantothenate Kinase 1 (PANK1) WB; IHC; ICC; IP.
PU143Mu01
Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Pantothenate Kinase 1 (PANK1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Pantothenate Kinase 1 (PANK1) CLIA assay for Antigen Detection
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Pantothenate Kinase 1 (PANK1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Pantothenate Kinase 1 (PANK1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Pantothenate Kinase 1 (PANK1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Pantothenate Kinase 1 (PANK1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Pantothenate Kinase 1 (PANK1) CLIA assay for Antigen Detection
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Pantothenate Kinase 1 (PANK1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Pantothenate Kinase 1 (PANK1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Pantothenate Kinase 1 (PANK1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Pantothenate Kinase 1 (PANK1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Pantothenate Kinase 1 (PANK1) CLIA assay for Antigen Detection
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Pantothenate Kinase 1 (PANK1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Pantothenate Kinase 1 (PANK1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Pantothenate Kinase 1 (PANK1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Pantothenate Kinase 1 (PANK1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Pantothenate Kinase 1 (PANK1) CLIA assay for Antigen Detection
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Pantothenate Kinase 1 (PANK1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Pantothenate Kinase 1 (PANK1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Pantothenate Kinase 1 (PANK1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Pantothenate Kinase 1 (PANK1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Pantothenate Kinase 1 (PANK1) CLIA assay for Antigen Detection
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Pantothenate Kinase 1 (PANK1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Pantothenate Kinase 1 (PANK1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Pantothenate Kinase 1 (PANK1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Pantothenate Kinase 1 (PANK1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Pantothenate Kinase 1 (PANK1) CLIA assay for Antigen Detection
Organism species: Chicken (Gallus)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Pantothenate Kinase 1 (PANK1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Pantothenate Kinase 1 (PANK1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Pantothenate Kinase 1 (PANK1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Pantothenate Kinase 1 (PANK1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Pantothenate Kinase 1 (PANK1) CLIA assay for Antigen Detection
Organism species: Ovis aries; Ovine (Sheep)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Pantothenate Kinase 1 (PANK1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Pantothenate Kinase 1 (PANK1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Pantothenate Kinase 1 (PANK1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Pantothenate Kinase 1 (PANK1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Pantothenate Kinase 1 (PANK1) CLIA assay for Antigen Detection
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Pantothenate Kinase 1 (PANK1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Pantothenate Kinase 1 (PANK1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Pantothenate Kinase 1 (PANK1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Pantothenate Kinase 1 (PANK1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Pantothenate Kinase 1 (PANK1) CLIA assay for Antigen Detection
Organism species: Cavia (Guinea pig )
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Pantothenate Kinase 1 (PANK1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Pantothenate Kinase 1 (PANK1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Pantothenate Kinase 1 (PANK1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Pantothenate Kinase 1 (PANK1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Pantothenate Kinase 1 (PANK1) CLIA assay for Antigen Detection
Organism species: Equus caballus; Equine (Horse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Pantothenate Kinase 1 (PANK1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Pantothenate Kinase 1 (PANK1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Pantothenate Kinase 1 (PANK1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Pantothenate Kinase 1 (PANK1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Pantothenate Kinase 1 (PANK1) CLIA assay for Antigen Detection
Organism species: Capra hircus; Caprine (Goat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Pantothenate Kinase 1 (PANK1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Pantothenate Kinase 1 (PANK1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Pantothenate Kinase 1 (PANK1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Pantothenate Kinase 1 (PANK1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Pantothenate Kinase 1 (PANK1) CLIA assay for Antigen Detection
Organism species: Pan-species (General)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Pantothenate Kinase 1 (PANK1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Pantothenate Kinase 1 (PANK1) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Pantothenate Kinase 1 (PANK1) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Pantothenate Kinase 1 (PANK1) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Pantothenate Kinase 1 (PANK1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Pantothenate Kinase 1 (PANK1) CLIA assay for Antigen Detection
Reference
"Cloning and characterization of a novel human pantothenate kinase gene." Int. J. Biochem. Cell Biol. 34:109-115(2002) [PubMed ] [Europe PMC ] [Abstract ]
"PPARalpha controls the intracellular coenzyme A concentration via regulation of PANK1alpha gene expression." J. Lipid Res. 45:17-31(2004) [PubMed ] [Europe PMC ] [Abstract ]
"The DNA sequence and comparative analysis of human chromosome 10." Nature 429:375-381(2004) [PubMed ] [Europe PMC ] [Abstract ]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." Genome Res. 14:2121-2127(2004) [PubMed ] [Europe PMC ] [Abstract ]
"A novel pantothenate kinase gene (PANK2) is defective in Hallervorden-Spatz syndrome." Nat. Genet. 28:345-349(2001) [PubMed ] [Europe PMC ] [Abstract ]
, Unpublished observations (JUL-2001)
"Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions." Sci. Signal. 2:RA46-RA46(2009) [PubMed ] [Europe PMC ] [Abstract ]
"Crystal structures of human pantothenate kinases. Insights into allosteric regulation and mutations linked to a neurodegeneration disorder." J. Biol. Chem. 282:27984-27993(2007) [PubMed ] [Europe PMC ] [Abstract ]
