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Prostate Stem Cell Antigen (PSCA)

Prostate stem cell antigen is a glycosylphosphatidylinositol-anchored cell membrane glycoprotein. In addition to being highly expressed in the prostate it is also expressed in the bladder, placenta, colon, kidney, and stomach. This gene is up-regulated in a large proportion of prostate cancers and is also detected in cancers of the bladder and pancreas. This gene has a nonsynonymous nucleotide polymorphism at its start codon.Highly expressed in prostate. Also found in bladder, placenta, stomach, colon and kidney. Overexpressed in prostate cancers and expression is correlated with tumor stage, grade and androgen-independence. Highly expressed in prostate cancer bone metastases. Expressed in gastric epithelial cells, mainly in the isthmus (at protein level). Not detected in normal intestinal epithelium (at protein level).

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins U122Hu01 Recombinant Prostate Stem Cell Antigen (PSCA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Prostate Stem Cell Antigen (PSCA) Bioactivity
Antibodies MU122Hu22 Monoclonal Antibody to Prostate Stem Cell Antigen (PSCA) WB; IHC; ICC; IP.
PU122Hu01 Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) WB; IHC; ICC; IF.
LU122Hu71 Biotin Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Flow Cytometry
LU122Hu81 FITC Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Flow Cytometry;ICC/IF
Assay Kits KEU122Hu ELISA Kit for Prostate Stem Cell Antigen (PSCA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Prostate Stem Cell Antigen (PSCA) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Prostate Stem Cell Antigen (PSCA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Prostate Stem Cell Antigen (PSCA) Bioactivity
Antibodies NONE Monoclonal Antibody to Prostate Stem Cell Antigen (PSCA) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Prostate Stem Cell Antigen (PSCA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Prostate Stem Cell Antigen (PSCA) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Prostate Stem Cell Antigen (PSCA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Prostate Stem Cell Antigen (PSCA) Bioactivity
Antibodies NONE Monoclonal Antibody to Prostate Stem Cell Antigen (PSCA) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Prostate Stem Cell Antigen (PSCA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Prostate Stem Cell Antigen (PSCA) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Prostate Stem Cell Antigen (PSCA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Prostate Stem Cell Antigen (PSCA) Bioactivity
Antibodies NONE Monoclonal Antibody to Prostate Stem Cell Antigen (PSCA) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Prostate Stem Cell Antigen (PSCA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Prostate Stem Cell Antigen (PSCA) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Prostate Stem Cell Antigen (PSCA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Prostate Stem Cell Antigen (PSCA) Bioactivity
Antibodies NONE Monoclonal Antibody to Prostate Stem Cell Antigen (PSCA) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Prostate Stem Cell Antigen (PSCA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Prostate Stem Cell Antigen (PSCA) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Prostate Stem Cell Antigen (PSCA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Prostate Stem Cell Antigen (PSCA) Bioactivity
Antibodies NONE Monoclonal Antibody to Prostate Stem Cell Antigen (PSCA) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Prostate Stem Cell Antigen (PSCA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Prostate Stem Cell Antigen (PSCA) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Prostate Stem Cell Antigen (PSCA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Prostate Stem Cell Antigen (PSCA) Bioactivity
Antibodies NONE Monoclonal Antibody to Prostate Stem Cell Antigen (PSCA) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Prostate Stem Cell Antigen (PSCA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Prostate Stem Cell Antigen (PSCA) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Prostate Stem Cell Antigen (PSCA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Prostate Stem Cell Antigen (PSCA) Bioactivity
Antibodies NONE Monoclonal Antibody to Prostate Stem Cell Antigen (PSCA) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Prostate Stem Cell Antigen (PSCA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Prostate Stem Cell Antigen (PSCA) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Prostate Stem Cell Antigen (PSCA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Prostate Stem Cell Antigen (PSCA) Bioactivity
Antibodies NONE Monoclonal Antibody to Prostate Stem Cell Antigen (PSCA) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Prostate Stem Cell Antigen (PSCA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Prostate Stem Cell Antigen (PSCA) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Prostate Stem Cell Antigen (PSCA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Prostate Stem Cell Antigen (PSCA) Bioactivity
Antibodies NONE Monoclonal Antibody to Prostate Stem Cell Antigen (PSCA) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Prostate Stem Cell Antigen (PSCA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Prostate Stem Cell Antigen (PSCA) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Prostate Stem Cell Antigen (PSCA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Prostate Stem Cell Antigen (PSCA) Bioactivity
Antibodies NONE Monoclonal Antibody to Prostate Stem Cell Antigen (PSCA) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Prostate Stem Cell Antigen (PSCA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Prostate Stem Cell Antigen (PSCA) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Prostate Stem Cell Antigen (PSCA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Prostate Stem Cell Antigen (PSCA) Bioactivity
Antibodies NONE Monoclonal Antibody to Prostate Stem Cell Antigen (PSCA) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Prostate Stem Cell Antigen (PSCA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Prostate Stem Cell Antigen (PSCA) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Prostate Stem Cell Antigen (PSCA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Prostate Stem Cell Antigen (PSCA) Bioactivity
Antibodies NONE Monoclonal Antibody to Prostate Stem Cell Antigen (PSCA) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Prostate Stem Cell Antigen (PSCA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Prostate Stem Cell Antigen (PSCA) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Prostate Stem Cell Antigen (PSCA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Prostate Stem Cell Antigen (PSCA) Bioactivity
Antibodies NONE Monoclonal Antibody to Prostate Stem Cell Antigen (PSCA) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Prostate Stem Cell Antigen (PSCA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Prostate Stem Cell Antigen (PSCA) CLIA assay for Antigen Detection

Reference

"Prostate stem cell antigen: a cell surface marker overexpressed in prostate cancer."
Proc. Natl. Acad. Sci. U.S.A. 95:1735-1740(1998) [PubMed] [Europe PMC] [Abstract]

"Reduced expression of PSCA, a member of the LY-6 family of cell surface antigens, in bladder, esophagus, and stomach tumors."
Biochem. Biophys. Res. Commun. 275:783-788(2000) [PubMed] [Europe PMC] [Abstract]

"DNA sequence and analysis of human chromosome 8."
Nature 439:331-335(2006) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]

"Signal peptide prediction based on analysis of experimentally verified cleavage sites."
Protein Sci. 13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]

"Prostate stem cell antigen (PSCA) expression increases with high gleason score, advanced stage and bone metastasis in prostate cancer."
Oncogene 19:1288-1296(2000) [PubMed] [Europe PMC] [Abstract]

"Genetic variation in PSCA is associated with susceptibility to diffuse-type gastric cancer."
Nat. Genet. 40:730-740(2008) [PubMed] [Europe PMC] [Abstract]