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Prostate Stem Cell Antigen (PSCA)
Prostate Stem Cell Antigen (PSCA)
Prostate stem cell antigen is a glycosylphosphatidylinositol-anchored cell membrane glycoprotein. In addition to being highly expressed in the prostate it is also expressed in the bladder, placenta, colon, kidney, and stomach. This gene is up-regulated in a large proportion of prostate cancers and is also detected in cancers of the bladder and pancreas. This gene has a nonsynonymous nucleotide polymorphism at its start codon.Highly expressed in prostate. Also found in bladder, placenta, stomach, colon and kidney. Overexpressed in prostate cancers and expression is correlated with tumor stage, grade and androgen-independence. Highly expressed in prostate cancer bone metastases. Expressed in gastric epithelial cells, mainly in the isthmus (at protein level). Not detected in normal intestinal epithelium (at protein level).
Organism species: Homo sapiens (Human)
Organism species: Mus musculus (Mouse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Prostate Stem Cell Antigen (PSCA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Prostate Stem Cell Antigen (PSCA) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Prostate Stem Cell Antigen (PSCA) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Prostate Stem Cell Antigen (PSCA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Prostate Stem Cell Antigen (PSCA) CLIA assay for Antigen Detection
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Prostate Stem Cell Antigen (PSCA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Prostate Stem Cell Antigen (PSCA) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Prostate Stem Cell Antigen (PSCA) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Prostate Stem Cell Antigen (PSCA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Prostate Stem Cell Antigen (PSCA) CLIA assay for Antigen Detection
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Prostate Stem Cell Antigen (PSCA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Prostate Stem Cell Antigen (PSCA) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Prostate Stem Cell Antigen (PSCA) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Prostate Stem Cell Antigen (PSCA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Prostate Stem Cell Antigen (PSCA) CLIA assay for Antigen Detection
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Prostate Stem Cell Antigen (PSCA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Prostate Stem Cell Antigen (PSCA) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Prostate Stem Cell Antigen (PSCA) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Prostate Stem Cell Antigen (PSCA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Prostate Stem Cell Antigen (PSCA) CLIA assay for Antigen Detection
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Prostate Stem Cell Antigen (PSCA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Prostate Stem Cell Antigen (PSCA) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Prostate Stem Cell Antigen (PSCA) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Prostate Stem Cell Antigen (PSCA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Prostate Stem Cell Antigen (PSCA) CLIA assay for Antigen Detection
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Prostate Stem Cell Antigen (PSCA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Prostate Stem Cell Antigen (PSCA) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Prostate Stem Cell Antigen (PSCA) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Prostate Stem Cell Antigen (PSCA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Prostate Stem Cell Antigen (PSCA) CLIA assay for Antigen Detection
Organism species: Chicken (Gallus)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Prostate Stem Cell Antigen (PSCA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Prostate Stem Cell Antigen (PSCA) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Prostate Stem Cell Antigen (PSCA) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Prostate Stem Cell Antigen (PSCA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Prostate Stem Cell Antigen (PSCA) CLIA assay for Antigen Detection
Organism species: Ovis aries; Ovine (Sheep)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Prostate Stem Cell Antigen (PSCA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Prostate Stem Cell Antigen (PSCA) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Prostate Stem Cell Antigen (PSCA) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Prostate Stem Cell Antigen (PSCA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Prostate Stem Cell Antigen (PSCA) CLIA assay for Antigen Detection
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Prostate Stem Cell Antigen (PSCA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Prostate Stem Cell Antigen (PSCA) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Prostate Stem Cell Antigen (PSCA) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Prostate Stem Cell Antigen (PSCA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Prostate Stem Cell Antigen (PSCA) CLIA assay for Antigen Detection
Organism species: Cavia (Guinea pig )
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Prostate Stem Cell Antigen (PSCA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Prostate Stem Cell Antigen (PSCA) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Prostate Stem Cell Antigen (PSCA) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Prostate Stem Cell Antigen (PSCA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Prostate Stem Cell Antigen (PSCA) CLIA assay for Antigen Detection
Organism species: Equus caballus; Equine (Horse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Prostate Stem Cell Antigen (PSCA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Prostate Stem Cell Antigen (PSCA) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Prostate Stem Cell Antigen (PSCA) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Prostate Stem Cell Antigen (PSCA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Prostate Stem Cell Antigen (PSCA) CLIA assay for Antigen Detection
Organism species: Capra hircus; Caprine (Goat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Prostate Stem Cell Antigen (PSCA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Prostate Stem Cell Antigen (PSCA) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Prostate Stem Cell Antigen (PSCA) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Prostate Stem Cell Antigen (PSCA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Prostate Stem Cell Antigen (PSCA) CLIA assay for Antigen Detection
Organism species: Pan-species (General)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Prostate Stem Cell Antigen (PSCA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Prostate Stem Cell Antigen (PSCA) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Prostate Stem Cell Antigen (PSCA) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Prostate Stem Cell Antigen (PSCA) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Prostate Stem Cell Antigen (PSCA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Prostate Stem Cell Antigen (PSCA) CLIA assay for Antigen Detection
Reference
"Prostate stem cell antigen: a cell surface marker overexpressed in prostate cancer." Proc. Natl. Acad. Sci. U.S.A. 95:1735-1740(1998) [PubMed ] [Europe PMC ] [Abstract ]
"Reduced expression of PSCA, a member of the LY-6 family of cell surface antigens, in bladder, esophagus, and stomach tumors." Biochem. Biophys. Res. Commun. 275:783-788(2000) [PubMed ] [Europe PMC ] [Abstract ]
"DNA sequence and analysis of human chromosome 8." Nature 439:331-335(2006) [PubMed ] [Europe PMC ] [Abstract ]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." Genome Res. 14:2121-2127(2004) [PubMed ] [Europe PMC ] [Abstract ]
"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed ] [Europe PMC ] [Abstract ]
"Signal peptide prediction based on analysis of experimentally verified cleavage sites." Protein Sci. 13:2819-2824(2004) [PubMed ] [Europe PMC ] [Abstract ]
"Prostate stem cell antigen (PSCA) expression increases with high gleason score, advanced stage and bone metastasis in prostate cancer." Oncogene 19:1288-1296(2000) [PubMed ] [Europe PMC ] [Abstract ]
"Genetic variation in PSCA is associated with susceptibility to diffuse-type gastric cancer." Nat. Genet. 40:730-740(2008) [PubMed ] [Europe PMC ] [Abstract ]