Call Now

Purine Rich Element Binding Protein A (PURA)

PUR-A; PUR1; PUR-ALPHA; PURALPHA; Transcriptional activator protein Pur-alpha; Purine-rich single-stranded DNA-binding protein alpha

Transcriptional activator protein Pur-alpha is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia.
This is a probable transcription activator that specifically binds the purine-rich single strand of the PUR element located upstream of the MYC gene. May play a role in the initiation of DNA replication and in recombination.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins U116Hu01 Recombinant Purine Rich Element Binding Protein A (PURA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Purine Rich Element Binding Protein A (PURA) Bioactivity
Antibodies NONE Monoclonal Antibody to Purine Rich Element Binding Protein A (PURA) WB; IHC; ICC; IP.
PU116Hu01 Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Purine Rich Element Binding Protein A (PURA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Purine Rich Element Binding Protein A (PURA) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Purine Rich Element Binding Protein A (PURA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Purine Rich Element Binding Protein A (PURA) Bioactivity
Antibodies NONE Monoclonal Antibody to Purine Rich Element Binding Protein A (PURA) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Purine Rich Element Binding Protein A (PURA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Purine Rich Element Binding Protein A (PURA) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Purine Rich Element Binding Protein A (PURA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Purine Rich Element Binding Protein A (PURA) Bioactivity
Antibodies NONE Monoclonal Antibody to Purine Rich Element Binding Protein A (PURA) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Purine Rich Element Binding Protein A (PURA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Purine Rich Element Binding Protein A (PURA) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Purine Rich Element Binding Protein A (PURA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Purine Rich Element Binding Protein A (PURA) Bioactivity
Antibodies NONE Monoclonal Antibody to Purine Rich Element Binding Protein A (PURA) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Purine Rich Element Binding Protein A (PURA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Purine Rich Element Binding Protein A (PURA) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Purine Rich Element Binding Protein A (PURA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Purine Rich Element Binding Protein A (PURA) Bioactivity
Antibodies NONE Monoclonal Antibody to Purine Rich Element Binding Protein A (PURA) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Purine Rich Element Binding Protein A (PURA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Purine Rich Element Binding Protein A (PURA) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Purine Rich Element Binding Protein A (PURA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Purine Rich Element Binding Protein A (PURA) Bioactivity
Antibodies NONE Monoclonal Antibody to Purine Rich Element Binding Protein A (PURA) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Purine Rich Element Binding Protein A (PURA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Purine Rich Element Binding Protein A (PURA) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Purine Rich Element Binding Protein A (PURA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Purine Rich Element Binding Protein A (PURA) Bioactivity
Antibodies NONE Monoclonal Antibody to Purine Rich Element Binding Protein A (PURA) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Purine Rich Element Binding Protein A (PURA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Purine Rich Element Binding Protein A (PURA) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Purine Rich Element Binding Protein A (PURA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Purine Rich Element Binding Protein A (PURA) Bioactivity
Antibodies NONE Monoclonal Antibody to Purine Rich Element Binding Protein A (PURA) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Purine Rich Element Binding Protein A (PURA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Purine Rich Element Binding Protein A (PURA) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Purine Rich Element Binding Protein A (PURA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Purine Rich Element Binding Protein A (PURA) Bioactivity
Antibodies NONE Monoclonal Antibody to Purine Rich Element Binding Protein A (PURA) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Purine Rich Element Binding Protein A (PURA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Purine Rich Element Binding Protein A (PURA) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Purine Rich Element Binding Protein A (PURA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Purine Rich Element Binding Protein A (PURA) Bioactivity
Antibodies NONE Monoclonal Antibody to Purine Rich Element Binding Protein A (PURA) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Purine Rich Element Binding Protein A (PURA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Purine Rich Element Binding Protein A (PURA) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Purine Rich Element Binding Protein A (PURA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Purine Rich Element Binding Protein A (PURA) Bioactivity
Antibodies NONE Monoclonal Antibody to Purine Rich Element Binding Protein A (PURA) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Purine Rich Element Binding Protein A (PURA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Purine Rich Element Binding Protein A (PURA) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Purine Rich Element Binding Protein A (PURA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Purine Rich Element Binding Protein A (PURA) Bioactivity
Antibodies NONE Monoclonal Antibody to Purine Rich Element Binding Protein A (PURA) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Purine Rich Element Binding Protein A (PURA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Purine Rich Element Binding Protein A (PURA) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Purine Rich Element Binding Protein A (PURA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Purine Rich Element Binding Protein A (PURA) Bioactivity
Antibodies NONE Monoclonal Antibody to Purine Rich Element Binding Protein A (PURA) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Purine Rich Element Binding Protein A (PURA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Purine Rich Element Binding Protein A (PURA) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Purine Rich Element Binding Protein A (PURA) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Purine Rich Element Binding Protein A (PURA) Bioactivity
Antibodies NONE Monoclonal Antibody to Purine Rich Element Binding Protein A (PURA) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Purine Rich Element Binding Protein A (PURA) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Purine Rich Element Binding Protein A (PURA) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Purine Rich Element Binding Protein A (PURA) CLIA assay for Antigen Detection

Reference

"Sequence of cDNA comprising the human pur gene and sequence-specific single-stranded-DNA-binding properties of the encoded protein."
Mol. Cell. Biol. 12:5673-5682(1992) [PubMed] [Europe PMC] [Abstract]

"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]

"Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]

"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]

"Initial characterization of the human central proteome."
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]

"Mutations in PURA cause profound neonatal hypotonia, seizures, and encephalopathy in 5q31.3 microdeletion syndrome."
Am. J. Hum. Genet. 95:579-583(2014) [PubMed] [Europe PMC] [Abstract]

"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]