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Perilipin 1 (PLIN1)

PERI; PLIN1; Lipid Droplet Associated Protein

Perilipin is a protein that coats lipid droplets in adipocytes, the fat-storing cells in adipose tissue. Perilipin acts as a protective coating from the body’s natural lipases, such as hormone-sensitive lipase,which break triglycerides into glycerol and free fatty acids for use in metabolism, a process called lipolysis.
Perilipin is hyperphosphorylated by PKA following β-adrenergic receptor activation. Phosphorylated perilipin changes conformation, exposing the stored lipids to hormone-sensitive lipase-mediated lipolysis. Although PKA also phosphorylates hormone-sensitive lipase, which can increase PKA activity, the more than 50-fold increase in fat mobilization (triggered by epinephrine) is primarily due to perilipin phosphorylation.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU112Hu01 Recombinant Perilipin 1 (PLIN1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU112Hu01 Monoclonal Antibody to Perilipin 1 (PLIN1) WB; IHC; ICC; IP.
PAU112Hu01 Polyclonal Antibody to Perilipin 1 (PLIN1) WB; IHC; ICC; IF.
Assay Kits CLU112Hu01 CLIA Kit for Perilipin 1 (PLIN1) CLIA assay for Antigen Detection
ELU112Hu01 ELISA Kit for Perilipin 1 (PLIN1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU112Mu01 Recombinant Perilipin 1 (PLIN1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU112Mu01 Monoclonal Antibody to Perilipin 1 (PLIN1) WB; IHC; ICC; IP.
PAU112Mu01 Polyclonal Antibody to Perilipin 1 (PLIN1) WB; IHC; ICC; IF.
Assay Kits CLU112Mu01 CLIA Kit for Perilipin 1 (PLIN1) CLIA assay for Antigen Detection
ELU112Mu01 ELISA Kit for Perilipin 1 (PLIN1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU112Ra01 Recombinant Perilipin 1 (PLIN1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU112Ra01 Monoclonal Antibody to Perilipin 1 (PLIN1) WB; IHC; ICC; IP.
PAU112Ra01 Polyclonal Antibody to Perilipin 1 (PLIN1) WB; IHC; ICC; IF.
Assay Kits CLU112Ra01 CLIA Kit for Perilipin 1 (PLIN1) CLIA assay for Antigen Detection
ELU112Ra01 ELISA Kit for Perilipin 1 (PLIN1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU112Ca01 Recombinant Perilipin 1 (PLIN1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU112Ca01 Monoclonal Antibody to Perilipin 1 (PLIN1) WB; IHC; ICC; IP.
PAU112Ca01 Polyclonal Antibody to Perilipin 1 (PLIN1) WB; IHC; ICC; IF.
Assay Kits CLU112Ca01 CLIA Kit for Perilipin 1 (PLIN1) CLIA assay for Antigen Detection
ELU112Ca01 ELISA Kit for Perilipin 1 (PLIN1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU112Po01 Recombinant Perilipin 1 (PLIN1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU112Po01 Monoclonal Antibody to Perilipin 1 (PLIN1) WB; IHC; ICC; IP.
PAU112Po01 Polyclonal Antibody to Perilipin 1 (PLIN1) WB; IHC; ICC; IF.
Assay Kits CLU112Po01 CLIA Kit for Perilipin 1 (PLIN1) CLIA assay for Antigen Detection
ELU112Po01 ELISA Kit for Perilipin 1 (PLIN1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU112Bo01 Recombinant Perilipin 1 (PLIN1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU112Bo01 Monoclonal Antibody to Perilipin 1 (PLIN1) WB; IHC; ICC; IP.
PAU112Bo01 Polyclonal Antibody to Perilipin 1 (PLIN1) WB; IHC; ICC; IF.
Assay Kits CLU112Bo01 CLIA Kit for Perilipin 1 (PLIN1) CLIA assay for Antigen Detection
ELU112Bo01 ELISA Kit for Perilipin 1 (PLIN1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU112Rb01 Recombinant Perilipin 1 (PLIN1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU112Rb01 Monoclonal Antibody to Perilipin 1 (PLIN1) WB; IHC; ICC; IP.
PAU112Rb01 Polyclonal Antibody to Perilipin 1 (PLIN1) WB; IHC; ICC; IF.
Assay Kits CLU112Rb01 CLIA Kit for Perilipin 1 (PLIN1) CLIA assay for Antigen Detection
ELU112Rb01 ELISA Kit for Perilipin 1 (PLIN1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPU112Mo01 Recombinant Perilipin 1 (PLIN1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAU112Mo01 Monoclonal Antibody to Perilipin 1 (PLIN1) WB; IHC; ICC; IP.
PAU112Mo01 Polyclonal Antibody to Perilipin 1 (PLIN1) WB; IHC; ICC; IF.
Assay Kits CLU112Mo01 CLIA Kit for Perilipin 1 (PLIN1) CLIA assay for Antigen Detection
ELU112Mo01 ELISA Kit for Perilipin 1 (PLIN1) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"Isolation and chromosomal mapping of the human homolog of perilipin (PLIN), a rat adipose tissue-specific gene, by differential display method."
Genomics 48:254-257(1998) [PubMed] [Europe PMC] [Abstract]

"Analysis of the DNA sequence and duplication history of human chromosome 15."
Nature 440:671-675(2006) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Perilipin deficiency and autosomal dominant partial lipodystrophy."
N. Engl. J. Med. 364:740-748(2011) [PubMed] [Europe PMC] [Abstract]

"FSP27 and PLIN1 interaction promotes the formation of large lipid droplets in human adipocytes."
Biochem. Biophys. Res. Commun. 432:296-301(2013) [PubMed] [Europe PMC] [Abstract]

"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]