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Plectin (PLEC)
Plectin (PLEC)
HD1; PCN; EBS1; EBSO; PLEC1b; PLTN; Hemidesmosomal protein 1; Intermediate Filament Binding Protein 500kDa; Epidermolysis Bullosa Simplex 1(Ogna)
Plectin is a prominent member of an important family of structurally and in part functionally related proteins, termed plakins or cytolinkers, that are capable of interlinking different elements of the cytoskeleton. Plakins, with their multi-domain structure and enormous size, not only play crucial roles in maintaining cell and tissue integrity and orchestrating dynamic changes in cytoarchitecture and cell shape, but also serve as scaffolding platforms for the assembly, positioning, and regulation of signaling complexes .
The plectin gene locus in mouse on chromosome 15 has been analyzed in detail , revealing a genomic exon-intron organization with well over 40 exons spanning over 62 kb and an unusual 5' transcript complexity of plectin isoforms.
Organism species: Homo sapiens (Human)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
U103Hu01
Recombinant Plectin (PLEC) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Plectin (PLEC) Bioactivity
Antibodies
MU103Hu22
Monoclonal Antibody to Plectin (PLEC) WB; IHC; ICC; IP.
PU103Hu01
Polyclonal Antibody to Plectin (PLEC) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Plectin (PLEC) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Plectin (PLEC) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Plectin (PLEC) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Plectin (PLEC) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Plectin (PLEC) Flow Cytometry;ICC/IF
Assay Kits
KEU103Hu
ELISA Kit for Plectin (PLEC) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Plectin (PLEC) CLIA assay for Antigen Detection
Organism species: Mus musculus (Mouse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Plectin (PLEC) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Plectin (PLEC) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Plectin (PLEC) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Plectin (PLEC) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Plectin (PLEC) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Plectin (PLEC) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Plectin (PLEC) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Plectin (PLEC) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Plectin (PLEC) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Plectin (PLEC) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Plectin (PLEC) CLIA assay for Antigen Detection
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Plectin (PLEC) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Plectin (PLEC) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Plectin (PLEC) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Plectin (PLEC) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Plectin (PLEC) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Plectin (PLEC) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Plectin (PLEC) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Plectin (PLEC) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Plectin (PLEC) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Plectin (PLEC) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Plectin (PLEC) CLIA assay for Antigen Detection
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Plectin (PLEC) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Plectin (PLEC) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Plectin (PLEC) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Plectin (PLEC) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Plectin (PLEC) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Plectin (PLEC) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Plectin (PLEC) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Plectin (PLEC) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Plectin (PLEC) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Plectin (PLEC) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Plectin (PLEC) CLIA assay for Antigen Detection
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Plectin (PLEC) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Plectin (PLEC) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Plectin (PLEC) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Plectin (PLEC) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Plectin (PLEC) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Plectin (PLEC) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Plectin (PLEC) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Plectin (PLEC) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Plectin (PLEC) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Plectin (PLEC) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Plectin (PLEC) CLIA assay for Antigen Detection
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Plectin (PLEC) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Plectin (PLEC) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Plectin (PLEC) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Plectin (PLEC) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Plectin (PLEC) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Plectin (PLEC) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Plectin (PLEC) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Plectin (PLEC) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Plectin (PLEC) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Plectin (PLEC) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Plectin (PLEC) CLIA assay for Antigen Detection
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Plectin (PLEC) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Plectin (PLEC) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Plectin (PLEC) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Plectin (PLEC) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Plectin (PLEC) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Plectin (PLEC) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Plectin (PLEC) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Plectin (PLEC) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Plectin (PLEC) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Plectin (PLEC) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Plectin (PLEC) CLIA assay for Antigen Detection
Organism species: Chicken (Gallus)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Plectin (PLEC) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Plectin (PLEC) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Plectin (PLEC) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Plectin (PLEC) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Plectin (PLEC) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Plectin (PLEC) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Plectin (PLEC) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Plectin (PLEC) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Plectin (PLEC) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Plectin (PLEC) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Plectin (PLEC) CLIA assay for Antigen Detection
Organism species: Ovis aries; Ovine (Sheep)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Plectin (PLEC) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Plectin (PLEC) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Plectin (PLEC) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Plectin (PLEC) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Plectin (PLEC) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Plectin (PLEC) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Plectin (PLEC) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Plectin (PLEC) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Plectin (PLEC) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Plectin (PLEC) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Plectin (PLEC) CLIA assay for Antigen Detection
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Plectin (PLEC) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Plectin (PLEC) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Plectin (PLEC) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Plectin (PLEC) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Plectin (PLEC) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Plectin (PLEC) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Plectin (PLEC) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Plectin (PLEC) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Plectin (PLEC) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Plectin (PLEC) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Plectin (PLEC) CLIA assay for Antigen Detection
Organism species: Cavia (Guinea pig )
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Plectin (PLEC) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Plectin (PLEC) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Plectin (PLEC) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Plectin (PLEC) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Plectin (PLEC) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Plectin (PLEC) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Plectin (PLEC) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Plectin (PLEC) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Plectin (PLEC) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Plectin (PLEC) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Plectin (PLEC) CLIA assay for Antigen Detection
Organism species: Equus caballus; Equine (Horse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Plectin (PLEC) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Plectin (PLEC) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Plectin (PLEC) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Plectin (PLEC) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Plectin (PLEC) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Plectin (PLEC) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Plectin (PLEC) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Plectin (PLEC) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Plectin (PLEC) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Plectin (PLEC) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Plectin (PLEC) CLIA assay for Antigen Detection
Organism species: Capra hircus; Caprine (Goat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Plectin (PLEC) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Plectin (PLEC) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Plectin (PLEC) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Plectin (PLEC) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Plectin (PLEC) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Plectin (PLEC) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Plectin (PLEC) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Plectin (PLEC) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Plectin (PLEC) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Plectin (PLEC) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Plectin (PLEC) CLIA assay for Antigen Detection
Organism species: Pan-species (General)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Plectin (PLEC) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Plectin (PLEC) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Plectin (PLEC) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Plectin (PLEC) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Plectin (PLEC) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Plectin (PLEC) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Plectin (PLEC) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Plectin (PLEC) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Plectin (PLEC) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Plectin (PLEC) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Plectin (PLEC) CLIA assay for Antigen Detection
Reference
"Human plectin: organization of the gene, sequence analysis, and chromosome localization (8q24)." Proc. Natl. Acad. Sci. U.S.A. 93:4278-4283(1996) [PubMed ] [Europe PMC ] [Abstract ]
"Loss of plectin causes epidermolysis bullosa with muscular dystrophy: cDNA cloning and genomic organization." Genes Dev. 10:1724-1735(1996) [PubMed ] [Europe PMC ] [Abstract ]
"Multiple variable first exons: a mechanism for cell- and tissue-specific gene regulation." Genome Res. 14:79-89(2004) [PubMed ] [Europe PMC ] [Abstract ]
"DNA sequence and analysis of human chromosome 8." Nature 439:331-335(2006) [PubMed ] [Europe PMC ] [Abstract ]