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Plectin (PLEC)

HD1; PCN; EBS1; EBSO; PLEC1b; PLTN; Hemidesmosomal protein 1; Intermediate Filament Binding Protein 500kDa; Epidermolysis Bullosa Simplex 1(Ogna)

Plectin is a prominent member of an important family of structurally and in part functionally related proteins, termed plakins or cytolinkers, that are capable of interlinking different elements of the cytoskeleton. Plakins, with their multi-domain structure and enormous size, not only play crucial roles in maintaining cell and tissue integrity and orchestrating dynamic changes in cytoarchitecture and cell shape, but also serve as scaffolding platforms for the assembly, positioning, and regulation of signaling complexes .
The plectin gene locus in mouse on chromosome 15 has been analyzed in detail , revealing a genomic exon-intron organization with well over 40 exons spanning over 62 kb and an unusual 5' transcript complexity of plectin isoforms.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins U103Hu01 Recombinant Plectin (PLEC) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Plectin (PLEC) Bioactivity
Antibodies MU103Hu22 Monoclonal Antibody to Plectin (PLEC) WB; IHC; ICC; IP.
PU103Hu01 Polyclonal Antibody to Plectin (PLEC) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Plectin (PLEC) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Plectin (PLEC) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Plectin (PLEC) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Plectin (PLEC) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Plectin (PLEC) Flow Cytometry;ICC/IF
Assay Kits KEU103Hu ELISA Kit for Plectin (PLEC) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Plectin (PLEC) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Plectin (PLEC) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Plectin (PLEC) Bioactivity
Antibodies NONE Monoclonal Antibody to Plectin (PLEC) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Plectin (PLEC) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Plectin (PLEC) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Plectin (PLEC) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Plectin (PLEC) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Plectin (PLEC) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Plectin (PLEC) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Plectin (PLEC) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Plectin (PLEC) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Plectin (PLEC) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Plectin (PLEC) Bioactivity
Antibodies NONE Monoclonal Antibody to Plectin (PLEC) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Plectin (PLEC) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Plectin (PLEC) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Plectin (PLEC) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Plectin (PLEC) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Plectin (PLEC) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Plectin (PLEC) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Plectin (PLEC) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Plectin (PLEC) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Plectin (PLEC) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Plectin (PLEC) Bioactivity
Antibodies NONE Monoclonal Antibody to Plectin (PLEC) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Plectin (PLEC) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Plectin (PLEC) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Plectin (PLEC) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Plectin (PLEC) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Plectin (PLEC) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Plectin (PLEC) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Plectin (PLEC) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Plectin (PLEC) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Plectin (PLEC) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Plectin (PLEC) Bioactivity
Antibodies NONE Monoclonal Antibody to Plectin (PLEC) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Plectin (PLEC) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Plectin (PLEC) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Plectin (PLEC) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Plectin (PLEC) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Plectin (PLEC) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Plectin (PLEC) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Plectin (PLEC) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Plectin (PLEC) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Plectin (PLEC) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Plectin (PLEC) Bioactivity
Antibodies NONE Monoclonal Antibody to Plectin (PLEC) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Plectin (PLEC) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Plectin (PLEC) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Plectin (PLEC) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Plectin (PLEC) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Plectin (PLEC) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Plectin (PLEC) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Plectin (PLEC) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Plectin (PLEC) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Plectin (PLEC) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Plectin (PLEC) Bioactivity
Antibodies NONE Monoclonal Antibody to Plectin (PLEC) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Plectin (PLEC) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Plectin (PLEC) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Plectin (PLEC) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Plectin (PLEC) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Plectin (PLEC) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Plectin (PLEC) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Plectin (PLEC) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Plectin (PLEC) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Plectin (PLEC) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Plectin (PLEC) Bioactivity
Antibodies NONE Monoclonal Antibody to Plectin (PLEC) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Plectin (PLEC) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Plectin (PLEC) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Plectin (PLEC) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Plectin (PLEC) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Plectin (PLEC) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Plectin (PLEC) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Plectin (PLEC) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Plectin (PLEC) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Plectin (PLEC) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Plectin (PLEC) Bioactivity
Antibodies NONE Monoclonal Antibody to Plectin (PLEC) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Plectin (PLEC) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Plectin (PLEC) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Plectin (PLEC) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Plectin (PLEC) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Plectin (PLEC) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Plectin (PLEC) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Plectin (PLEC) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Plectin (PLEC) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Plectin (PLEC) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Plectin (PLEC) Bioactivity
Antibodies NONE Monoclonal Antibody to Plectin (PLEC) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Plectin (PLEC) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Plectin (PLEC) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Plectin (PLEC) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Plectin (PLEC) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Plectin (PLEC) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Plectin (PLEC) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Plectin (PLEC) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Plectin (PLEC) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Plectin (PLEC) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Plectin (PLEC) Bioactivity
Antibodies NONE Monoclonal Antibody to Plectin (PLEC) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Plectin (PLEC) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Plectin (PLEC) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Plectin (PLEC) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Plectin (PLEC) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Plectin (PLEC) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Plectin (PLEC) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Plectin (PLEC) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Plectin (PLEC) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Plectin (PLEC) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Plectin (PLEC) Bioactivity
Antibodies NONE Monoclonal Antibody to Plectin (PLEC) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Plectin (PLEC) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Plectin (PLEC) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Plectin (PLEC) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Plectin (PLEC) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Plectin (PLEC) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Plectin (PLEC) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Plectin (PLEC) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Plectin (PLEC) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Plectin (PLEC) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Plectin (PLEC) Bioactivity
Antibodies NONE Monoclonal Antibody to Plectin (PLEC) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Plectin (PLEC) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Plectin (PLEC) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Plectin (PLEC) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Plectin (PLEC) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Plectin (PLEC) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Plectin (PLEC) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Plectin (PLEC) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Plectin (PLEC) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Plectin (PLEC) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Plectin (PLEC) Bioactivity
Antibodies NONE Monoclonal Antibody to Plectin (PLEC) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Plectin (PLEC) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Plectin (PLEC) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Plectin (PLEC) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Plectin (PLEC) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Plectin (PLEC) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Plectin (PLEC) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Plectin (PLEC) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Plectin (PLEC) CLIA assay for Antigen Detection

Reference

"Human plectin: organization of the gene, sequence analysis, and chromosome localization (8q24)."
Proc. Natl. Acad. Sci. U.S.A. 93:4278-4283(1996) [PubMed] [Europe PMC] [Abstract]

"Loss of plectin causes epidermolysis bullosa with muscular dystrophy: cDNA cloning and genomic organization."
Genes Dev. 10:1724-1735(1996) [PubMed] [Europe PMC] [Abstract]

"Multiple variable first exons: a mechanism for cell- and tissue-specific gene regulation."
Genome Res. 14:79-89(2004) [PubMed] [Europe PMC] [Abstract]

"DNA sequence and analysis of human chromosome 8."
Nature 439:331-335(2006) [PubMed] [Europe PMC] [Abstract]