Renin Binding Protein (RENBP)

RBP; RNBP; AGE; N-Acylglucosamine 2-Epimerase; GlcNAc 2-Epimerase; N-Acetyl-D-Glucosamine 2-Epimerase

SPN	U093
HGNC	9959
MGI	105940
PubMed	12866502
RGD	621688
UniProt	P51606
Wiki	RENBP

Renin-binding protein, originally isolated from porcine kidney, is a proteinaceous renin inhibitor. In inhibiting renin, the protein forms a complex with it, so-called high molecular weight renin. The nucleotide sequences of cDNAs encoding the porcine, human, and rat renin-binding proteins, the predicted amino acid sequences consist of 402, 417, and 419 amino acids, respectively. Sequences of the three are highly homologous. The leucine zipper motif, which is a key structure for the formation of a heterodimer or a homodimer of several proteins, was also conserved in each RENBP. it spans about 10 kb and consists of 11 exons separated by 10 introns. By polymerase chain reaction amplification of hybrid DNAs from human and hamster somatic cells, they demonstrated that the RENBP gene is located on the X chromosome.

Organism species: Homo sapiens (Human)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPU093Hu01	Recombinant Renin Binding Protein (RENBP)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAU093Hu01	Monoclonal Antibody to Renin Binding Protein (RENBP)	WB; IHC; ICC; IP.
Antibodies	PAU093Hu01	Polyclonal Antibody to Renin Binding Protein (RENBP)	WB; IHC; ICC; IF.
Assay Kits	CLU093Hu01	CLIA Kit for Renin Binding Protein (RENBP)	CLIA assay for Antigen Detection
Assay Kits	ELU093Hu01	ELISA Kit for Renin Binding Protein (RENBP)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPU093Mu01	Recombinant Renin Binding Protein (RENBP)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAU093Mu01	Monoclonal Antibody to Renin Binding Protein (RENBP)	WB; IHC; ICC; IP.
Antibodies	PAU093Mu01	Polyclonal Antibody to Renin Binding Protein (RENBP)	WB; IHC; ICC; IF.
Assay Kits	CLU093Mu01	CLIA Kit for Renin Binding Protein (RENBP)	CLIA assay for Antigen Detection
Assay Kits	ELU093Mu01	ELISA Kit for Renin Binding Protein (RENBP)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPU093Ra01	Recombinant Renin Binding Protein (RENBP)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAU093Ra01	Monoclonal Antibody to Renin Binding Protein (RENBP)	WB; IHC; ICC; IP.
Antibodies	PAU093Ra01	Polyclonal Antibody to Renin Binding Protein (RENBP)	WB; IHC; ICC; IF.
Assay Kits	CLU093Ra01	CLIA Kit for Renin Binding Protein (RENBP)	CLIA assay for Antigen Detection
Assay Kits	ELU093Ra01	ELISA Kit for Renin Binding Protein (RENBP)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPU093Ca01	Recombinant Renin Binding Protein (RENBP)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAU093Ca01	Monoclonal Antibody to Renin Binding Protein (RENBP)	WB; IHC; ICC; IP.
Antibodies	PAU093Ca01	Polyclonal Antibody to Renin Binding Protein (RENBP)	WB; IHC; ICC; IF.
Assay Kits	CLU093Ca01	CLIA Kit for Renin Binding Protein (RENBP)	CLIA assay for Antigen Detection
Assay Kits	ELU093Ca01	ELISA Kit for Renin Binding Protein (RENBP)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPU093Po01	Recombinant Renin Binding Protein (RENBP)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAU093Po01	Monoclonal Antibody to Renin Binding Protein (RENBP)	WB; IHC; ICC; IP.
Antibodies	PAU093Po01	Polyclonal Antibody to Renin Binding Protein (RENBP)	WB; IHC; ICC; IF.
Assay Kits	CLU093Po01	CLIA Kit for Renin Binding Protein (RENBP)	CLIA assay for Antigen Detection
Assay Kits	ELU093Po01	ELISA Kit for Renin Binding Protein (RENBP)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPU093Bo01	Recombinant Renin Binding Protein (RENBP)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAU093Bo01	Monoclonal Antibody to Renin Binding Protein (RENBP)	WB; IHC; ICC; IP.
Antibodies	PAU093Bo01	Polyclonal Antibody to Renin Binding Protein (RENBP)	WB; IHC; ICC; IF.
Assay Kits	CLU093Bo01	CLIA Kit for Renin Binding Protein (RENBP)	CLIA assay for Antigen Detection
Assay Kits	ELU093Bo01	ELISA Kit for Renin Binding Protein (RENBP)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPU093Rb01	Recombinant Renin Binding Protein (RENBP)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAU093Rb01	Monoclonal Antibody to Renin Binding Protein (RENBP)	WB; IHC; ICC; IP.
Antibodies	PAU093Rb01	Polyclonal Antibody to Renin Binding Protein (RENBP)	WB; IHC; ICC; IF.
Assay Kits	CLU093Rb01	CLIA Kit for Renin Binding Protein (RENBP)	CLIA assay for Antigen Detection
Assay Kits	ELU093Rb01	ELISA Kit for Renin Binding Protein (RENBP)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPU093Mo01	Recombinant Renin Binding Protein (RENBP)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAU093Mo01	Monoclonal Antibody to Renin Binding Protein (RENBP)	WB; IHC; ICC; IP.
Antibodies	PAU093Mo01	Polyclonal Antibody to Renin Binding Protein (RENBP)	WB; IHC; ICC; IF.
Assay Kits	CLU093Mo01	CLIA Kit for Renin Binding Protein (RENBP)	CLIA assay for Antigen Detection
Assay Kits	ELU093Mo01	ELISA Kit for Renin Binding Protein (RENBP)	Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence of the human X chromosome."
Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Genetic and molecular properties of human and rat renin-binding proteins with reference to the function of the leucine zipper motif."
J. Biochem. 110:493-500(1991) [PubMed] [Europe PMC] [Abstract]

"Human renin-binding protein is the enzyme N-acetyl-D-glucosamine 2-epimerase."
J. Biochem. 125:348-353(1999) [PubMed] [Europe PMC] [Abstract]

"Metabolism of vertebrate amino sugars with N-glycolyl groups: elucidating the intracellular fate of the non-human sialic acid N-glycolylneuraminic acid."
J. Biol. Chem. 287:28865-28881(2012) [PubMed] [Europe PMC] [Abstract]