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Radixin (RDX)
Radixin (RDX)
DFNB24; Deafness,Autosomal Recessive 24
Radixin is a cytoskeletal protein that may be important in linking actin to the plasma membrane. It is highly similar in sequence to both ezrin and moesin. The radixin gene has been localized by fluorescence in situ hybridization to 11q23. A truncated version representing a pseudogene (RDXP2) was assigned to Xp21.3. Another pseudogene that seemed to lack introns (RDXP1) was mapped to 11p by Southern and PCR analyses.
The major full-length protein contains 627 amino acids forming 3 known functional domains: an N-terminal FERM domain that localizes the protein to the plasma membrane, a central helical alpha-domain, and a C-terminal actin-binding domain. By immunohistochemical analysis of mouse inner ear.
Organism species: Homo sapiens (Human)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
U083Hu01
Recombinant Radixin (RDX) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Radixin (RDX) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Radixin (RDX) WB; IHC; ICC; IP.
PU083Hu01
Polyclonal Antibody to Radixin (RDX) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Radixin (RDX) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Radixin (RDX) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Radixin (RDX) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Radixin (RDX) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Radixin (RDX) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Radixin (RDX) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Radixin (RDX) CLIA assay for Antigen Detection
Organism species: Mus musculus (Mouse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Radixin (RDX) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Radixin (RDX) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Radixin (RDX) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Radixin (RDX) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Radixin (RDX) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Radixin (RDX) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Radixin (RDX) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Radixin (RDX) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Radixin (RDX) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Radixin (RDX) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Radixin (RDX) CLIA assay for Antigen Detection
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Radixin (RDX) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Radixin (RDX) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Radixin (RDX) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Radixin (RDX) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Radixin (RDX) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Radixin (RDX) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Radixin (RDX) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Radixin (RDX) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Radixin (RDX) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Radixin (RDX) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Radixin (RDX) CLIA assay for Antigen Detection
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Radixin (RDX) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Radixin (RDX) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Radixin (RDX) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Radixin (RDX) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Radixin (RDX) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Radixin (RDX) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Radixin (RDX) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Radixin (RDX) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Radixin (RDX) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Radixin (RDX) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Radixin (RDX) CLIA assay for Antigen Detection
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Radixin (RDX) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Radixin (RDX) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Radixin (RDX) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Radixin (RDX) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Radixin (RDX) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Radixin (RDX) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Radixin (RDX) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Radixin (RDX) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Radixin (RDX) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Radixin (RDX) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Radixin (RDX) CLIA assay for Antigen Detection
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Radixin (RDX) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Radixin (RDX) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Radixin (RDX) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Radixin (RDX) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Radixin (RDX) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Radixin (RDX) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Radixin (RDX) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Radixin (RDX) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Radixin (RDX) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Radixin (RDX) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Radixin (RDX) CLIA assay for Antigen Detection
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Radixin (RDX) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Radixin (RDX) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Radixin (RDX) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Radixin (RDX) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Radixin (RDX) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Radixin (RDX) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Radixin (RDX) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Radixin (RDX) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Radixin (RDX) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Radixin (RDX) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Radixin (RDX) CLIA assay for Antigen Detection
Organism species: Chicken (Gallus)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Radixin (RDX) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Radixin (RDX) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Radixin (RDX) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Radixin (RDX) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Radixin (RDX) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Radixin (RDX) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Radixin (RDX) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Radixin (RDX) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Radixin (RDX) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Radixin (RDX) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Radixin (RDX) CLIA assay for Antigen Detection
Organism species: Ovis aries; Ovine (Sheep)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Radixin (RDX) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Radixin (RDX) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Radixin (RDX) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Radixin (RDX) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Radixin (RDX) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Radixin (RDX) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Radixin (RDX) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Radixin (RDX) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Radixin (RDX) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Radixin (RDX) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Radixin (RDX) CLIA assay for Antigen Detection
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Radixin (RDX) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Radixin (RDX) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Radixin (RDX) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Radixin (RDX) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Radixin (RDX) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Radixin (RDX) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Radixin (RDX) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Radixin (RDX) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Radixin (RDX) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Radixin (RDX) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Radixin (RDX) CLIA assay for Antigen Detection
Organism species: Cavia (Guinea pig )
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Radixin (RDX) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Radixin (RDX) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Radixin (RDX) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Radixin (RDX) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Radixin (RDX) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Radixin (RDX) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Radixin (RDX) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Radixin (RDX) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Radixin (RDX) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Radixin (RDX) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Radixin (RDX) CLIA assay for Antigen Detection
Organism species: Equus caballus; Equine (Horse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Radixin (RDX) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Radixin (RDX) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Radixin (RDX) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Radixin (RDX) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Radixin (RDX) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Radixin (RDX) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Radixin (RDX) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Radixin (RDX) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Radixin (RDX) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Radixin (RDX) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Radixin (RDX) CLIA assay for Antigen Detection
Organism species: Capra hircus; Caprine (Goat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Radixin (RDX) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Radixin (RDX) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Radixin (RDX) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Radixin (RDX) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Radixin (RDX) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Radixin (RDX) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Radixin (RDX) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Radixin (RDX) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Radixin (RDX) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Radixin (RDX) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Radixin (RDX) CLIA assay for Antigen Detection
Organism species: Pan-species (General)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Radixin (RDX) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Radixin (RDX) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Radixin (RDX) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Radixin (RDX) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Radixin (RDX) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Radixin (RDX) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Radixin (RDX) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Radixin (RDX) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Radixin (RDX) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Radixin (RDX) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Radixin (RDX) CLIA assay for Antigen Detection
Reference
"Molecular cloning, cDNA sequence, and chromosomal assignment of the human radixin gene and two dispersed pseudogenes." Genomics 16:199-206(1993) [PubMed ] [Europe PMC ] [Abstract ]
"Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed ] [Europe PMC ] [Abstract ]
"Mutations of the RDX gene cause nonsyndromic hearing loss at the DFNB24 locus." Hum. Mutat. 28:417-423(2007) [PubMed ] [Europe PMC ] [Abstract ]
"Human chromosome 11 DNA sequence and analysis including novel gene identification." Nature 440:497-500(2006) [PubMed ] [Europe PMC ] [Abstract ]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." Genome Res. 14:2121-2127(2004) [PubMed ] [Europe PMC ] [Abstract ]
"NHE-RF, a regulatory cofactor for Na(+)-H+ exchange, is a common interactor for merlin and ERM (MERM) proteins." J. Biol. Chem. 273:1273-1276(1998) [PubMed ] [Europe PMC ] [Abstract ]
"Initial characterization of the human central proteome." BMC Syst. Biol. 5:17-17(2011) [PubMed ] [Europe PMC ] [Abstract ]
"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome." J. Proteomics 96:253-262(2014) [PubMed ] [Europe PMC ] [Abstract ]
