Tissue Specific Transplantation Antigen P35B (TSTA3)
FX; P35B; SDR4E1; Short-chain dehydrogenase/reductase family 4E member 1; GDP-L-Fucose Synthase; GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase
Tissue specific transplantation antigen P35B is a NADP(H)-binding protein. It catalyze the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose.
GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in this gene may cause leukocyte adhesion deficiency, type II. Two step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU039Hu01 | Recombinant Tissue Specific Transplantation Antigen P35B (TSTA3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU039Hu01 | Monoclonal Antibody to Tissue Specific Transplantation Antigen P35B (TSTA3) | WB; IHC; ICC; IP. |
| PAU039Hu01 | Polyclonal Antibody to Tissue Specific Transplantation Antigen P35B (TSTA3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU039Hu01 | CLIA Kit for Tissue Specific Transplantation Antigen P35B (TSTA3) | CLIA assay for Antigen Detection |
| ELU039Hu01 | ELISA Kit for Tissue Specific Transplantation Antigen P35B (TSTA3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU039Mu01 | Recombinant Tissue Specific Transplantation Antigen P35B (TSTA3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU039Mu01 | Monoclonal Antibody to Tissue Specific Transplantation Antigen P35B (TSTA3) | WB; IHC; ICC; IP. |
| PAU039Mu01 | Polyclonal Antibody to Tissue Specific Transplantation Antigen P35B (TSTA3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU039Mu01 | CLIA Kit for Tissue Specific Transplantation Antigen P35B (TSTA3) | CLIA assay for Antigen Detection |
| ELU039Mu01 | ELISA Kit for Tissue Specific Transplantation Antigen P35B (TSTA3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU039Ra01 | Recombinant Tissue Specific Transplantation Antigen P35B (TSTA3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU039Ra01 | Monoclonal Antibody to Tissue Specific Transplantation Antigen P35B (TSTA3) | WB; IHC; ICC; IP. |
| PAU039Ra01 | Polyclonal Antibody to Tissue Specific Transplantation Antigen P35B (TSTA3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU039Ra01 | CLIA Kit for Tissue Specific Transplantation Antigen P35B (TSTA3) | CLIA assay for Antigen Detection |
| ELU039Ra01 | ELISA Kit for Tissue Specific Transplantation Antigen P35B (TSTA3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU039Ca01 | Recombinant Tissue Specific Transplantation Antigen P35B (TSTA3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU039Ca01 | Monoclonal Antibody to Tissue Specific Transplantation Antigen P35B (TSTA3) | WB; IHC; ICC; IP. |
| PAU039Ca01 | Polyclonal Antibody to Tissue Specific Transplantation Antigen P35B (TSTA3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU039Ca01 | CLIA Kit for Tissue Specific Transplantation Antigen P35B (TSTA3) | CLIA assay for Antigen Detection |
| ELU039Ca01 | ELISA Kit for Tissue Specific Transplantation Antigen P35B (TSTA3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU039Po01 | Recombinant Tissue Specific Transplantation Antigen P35B (TSTA3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU039Po01 | Monoclonal Antibody to Tissue Specific Transplantation Antigen P35B (TSTA3) | WB; IHC; ICC; IP. |
| PAU039Po01 | Polyclonal Antibody to Tissue Specific Transplantation Antigen P35B (TSTA3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU039Po01 | CLIA Kit for Tissue Specific Transplantation Antigen P35B (TSTA3) | CLIA assay for Antigen Detection |
| ELU039Po01 | ELISA Kit for Tissue Specific Transplantation Antigen P35B (TSTA3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU039Bo01 | Recombinant Tissue Specific Transplantation Antigen P35B (TSTA3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU039Bo01 | Monoclonal Antibody to Tissue Specific Transplantation Antigen P35B (TSTA3) | WB; IHC; ICC; IP. |
| PAU039Bo01 | Polyclonal Antibody to Tissue Specific Transplantation Antigen P35B (TSTA3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU039Bo01 | CLIA Kit for Tissue Specific Transplantation Antigen P35B (TSTA3) | CLIA assay for Antigen Detection |
| ELU039Bo01 | ELISA Kit for Tissue Specific Transplantation Antigen P35B (TSTA3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU039Rb01 | Recombinant Tissue Specific Transplantation Antigen P35B (TSTA3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU039Rb01 | Monoclonal Antibody to Tissue Specific Transplantation Antigen P35B (TSTA3) | WB; IHC; ICC; IP. |
| PAU039Rb01 | Polyclonal Antibody to Tissue Specific Transplantation Antigen P35B (TSTA3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU039Rb01 | CLIA Kit for Tissue Specific Transplantation Antigen P35B (TSTA3) | CLIA assay for Antigen Detection |
| ELU039Rb01 | ELISA Kit for Tissue Specific Transplantation Antigen P35B (TSTA3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU039Mo01 | Recombinant Tissue Specific Transplantation Antigen P35B (TSTA3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU039Mo01 | Monoclonal Antibody to Tissue Specific Transplantation Antigen P35B (TSTA3) | WB; IHC; ICC; IP. |
| PAU039Mo01 | Polyclonal Antibody to Tissue Specific Transplantation Antigen P35B (TSTA3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU039Mo01 | CLIA Kit for Tissue Specific Transplantation Antigen P35B (TSTA3) | CLIA assay for Antigen Detection |
| ELU039Mo01 | ELISA Kit for Tissue Specific Transplantation Antigen P35B (TSTA3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Synthesis of GDP-L-fucose by the human FX protein."
J. Biol. Chem. 271:27274-27279(1996) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Primary structure of human erythrocyte nicotinamide adenine dinucleotide phosphate (NADP[H])-binding protein FX: identification with the mouse tum-transplantation antigen P35B."
Blood 85:264-267(1995) [PubMed] [Europe PMC] [Abstract]
"Initial characterization of the human central proteome."
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
"The crystal structure of human GDP-L-fucose synthase."
Acta Biochim. Biophys. Sin. 45:720-725(2013) [PubMed] [Europe PMC] [Abstract]
"Crystal structure of human GDP-L-fucose synthase with bound NADP."
Submitted (APR-2013) to the PDB data bank