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Secretogranin V (SCG5)
Secretogranin V (SCG5)
SCGV; P7B2; SGNE1; SgV; 7B2 Protein; Neuroendocrine protein 7B2; Prohormone Convertase Chaperone; Pituitary polypeptide; Secretory granule endocrine protein I
Neuroendocrine protein 7B2 is widely distributed in neuroendocrine tissues. It functions as a chaperone protein for the proprotein convertase PC2 and is required for the production of an active PC2 enzyme.
Acts as a molecular chaperone for PCSK2/PC2, preventing its premature activation in the regulated secretory pathway. Binds to inactive PCSK2 in the endoplasmic reticulum and facilitates its transport from there to later compartments of the secretory pathway where it is proteolytically matured and activated. Also required for cleavage of PCSK2 but does not appear to be involved in its folding. Plays a role in regulating pituitary hormone secretion. The C-terminal peptide inhibits PCSK2 in vitro.
Organism species: Homo sapiens (Human)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
U023Hu01
Recombinant Secretogranin V (SCG5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Secretogranin V (SCG5) Bioactivity
Antibodies
MU023Hu22
Monoclonal Antibody to Secretogranin V (SCG5) WB; IHC; ICC; IP.
PU023Hu01
Polyclonal Antibody to Secretogranin V (SCG5) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Secretogranin V (SCG5) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Secretogranin V (SCG5) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Secretogranin V (SCG5) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Secretogranin V (SCG5) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Secretogranin V (SCG5) Flow Cytometry;ICC/IF
Assay Kits
KEU023Hu
ELISA Kit for Secretogranin V (SCG5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Secretogranin V (SCG5) CLIA assay for Antigen Detection
Organism species: Mus musculus (Mouse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Secretogranin V (SCG5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Secretogranin V (SCG5) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Secretogranin V (SCG5) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Secretogranin V (SCG5) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Secretogranin V (SCG5) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Secretogranin V (SCG5) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Secretogranin V (SCG5) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Secretogranin V (SCG5) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Secretogranin V (SCG5) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Secretogranin V (SCG5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Secretogranin V (SCG5) CLIA assay for Antigen Detection
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Secretogranin V (SCG5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Secretogranin V (SCG5) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Secretogranin V (SCG5) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Secretogranin V (SCG5) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Secretogranin V (SCG5) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Secretogranin V (SCG5) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Secretogranin V (SCG5) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Secretogranin V (SCG5) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Secretogranin V (SCG5) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Secretogranin V (SCG5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Secretogranin V (SCG5) CLIA assay for Antigen Detection
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Secretogranin V (SCG5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Secretogranin V (SCG5) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Secretogranin V (SCG5) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Secretogranin V (SCG5) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Secretogranin V (SCG5) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Secretogranin V (SCG5) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Secretogranin V (SCG5) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Secretogranin V (SCG5) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Secretogranin V (SCG5) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Secretogranin V (SCG5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Secretogranin V (SCG5) CLIA assay for Antigen Detection
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Secretogranin V (SCG5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Secretogranin V (SCG5) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Secretogranin V (SCG5) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Secretogranin V (SCG5) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Secretogranin V (SCG5) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Secretogranin V (SCG5) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Secretogranin V (SCG5) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Secretogranin V (SCG5) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Secretogranin V (SCG5) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Secretogranin V (SCG5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Secretogranin V (SCG5) CLIA assay for Antigen Detection
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Secretogranin V (SCG5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Secretogranin V (SCG5) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Secretogranin V (SCG5) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Secretogranin V (SCG5) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Secretogranin V (SCG5) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Secretogranin V (SCG5) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Secretogranin V (SCG5) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Secretogranin V (SCG5) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Secretogranin V (SCG5) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Secretogranin V (SCG5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Secretogranin V (SCG5) CLIA assay for Antigen Detection
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Secretogranin V (SCG5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Secretogranin V (SCG5) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Secretogranin V (SCG5) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Secretogranin V (SCG5) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Secretogranin V (SCG5) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Secretogranin V (SCG5) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Secretogranin V (SCG5) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Secretogranin V (SCG5) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Secretogranin V (SCG5) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Secretogranin V (SCG5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Secretogranin V (SCG5) CLIA assay for Antigen Detection
Organism species: Chicken (Gallus)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Secretogranin V (SCG5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Secretogranin V (SCG5) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Secretogranin V (SCG5) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Secretogranin V (SCG5) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Secretogranin V (SCG5) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Secretogranin V (SCG5) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Secretogranin V (SCG5) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Secretogranin V (SCG5) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Secretogranin V (SCG5) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Secretogranin V (SCG5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Secretogranin V (SCG5) CLIA assay for Antigen Detection
Organism species: Ovis aries; Ovine (Sheep)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Secretogranin V (SCG5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Secretogranin V (SCG5) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Secretogranin V (SCG5) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Secretogranin V (SCG5) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Secretogranin V (SCG5) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Secretogranin V (SCG5) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Secretogranin V (SCG5) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Secretogranin V (SCG5) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Secretogranin V (SCG5) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Secretogranin V (SCG5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Secretogranin V (SCG5) CLIA assay for Antigen Detection
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Secretogranin V (SCG5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Secretogranin V (SCG5) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Secretogranin V (SCG5) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Secretogranin V (SCG5) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Secretogranin V (SCG5) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Secretogranin V (SCG5) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Secretogranin V (SCG5) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Secretogranin V (SCG5) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Secretogranin V (SCG5) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Secretogranin V (SCG5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Secretogranin V (SCG5) CLIA assay for Antigen Detection
Organism species: Cavia (Guinea pig )
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Secretogranin V (SCG5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Secretogranin V (SCG5) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Secretogranin V (SCG5) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Secretogranin V (SCG5) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Secretogranin V (SCG5) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Secretogranin V (SCG5) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Secretogranin V (SCG5) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Secretogranin V (SCG5) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Secretogranin V (SCG5) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Secretogranin V (SCG5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Secretogranin V (SCG5) CLIA assay for Antigen Detection
Organism species: Equus caballus; Equine (Horse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Secretogranin V (SCG5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Secretogranin V (SCG5) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Secretogranin V (SCG5) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Secretogranin V (SCG5) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Secretogranin V (SCG5) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Secretogranin V (SCG5) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Secretogranin V (SCG5) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Secretogranin V (SCG5) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Secretogranin V (SCG5) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Secretogranin V (SCG5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Secretogranin V (SCG5) CLIA assay for Antigen Detection
Organism species: Capra hircus; Caprine (Goat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Secretogranin V (SCG5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Secretogranin V (SCG5) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Secretogranin V (SCG5) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Secretogranin V (SCG5) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Secretogranin V (SCG5) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Secretogranin V (SCG5) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Secretogranin V (SCG5) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Secretogranin V (SCG5) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Secretogranin V (SCG5) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Secretogranin V (SCG5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Secretogranin V (SCG5) CLIA assay for Antigen Detection
Organism species: Pan-species (General)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Secretogranin V (SCG5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Secretogranin V (SCG5) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Secretogranin V (SCG5) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Secretogranin V (SCG5) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Secretogranin V (SCG5) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Secretogranin V (SCG5) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Secretogranin V (SCG5) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Secretogranin V (SCG5) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Secretogranin V (SCG5) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Secretogranin V (SCG5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Secretogranin V (SCG5) CLIA assay for Antigen Detection
Reference
"Cloning and sequence analysis of human pituitary cDNA encoding the novel polypeptide 7B2." FEBS Lett. 234:160-164(1988) [PubMed ] [Europe PMC ] [Abstract ]
"The production by alternate splicing of two mRNAs differing by one codon could be an intrinsic property of neuroendocrine protein 7B2 gene expression in man." Biochem. Biophys. Res. Commun. 174:156-162(1991) [PubMed ] [Europe PMC ] [Abstract ]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." Genome Res. 14:2121-2127(2004) [PubMed ] [Europe PMC ] [Abstract ]
"Structural organization of the gene encoding the neuroendocrine chaperone 7B2." Eur. J. Biochem. 236:60-67(1996) [PubMed ] [Europe PMC ] [Abstract ]
"Isolation and NH2-terminal sequence of a highly conserved human and porcine pituitary protein belonging to a new superfamily. Immunocytochemical localization in pars distalis and pars nervosa of the pituitary and in the supraoptic nucleus of the hypothalamus." Arch. Biochem. Biophys. 225:525-534(1983) [PubMed ] [Europe PMC ] [Abstract ]
"7B2 is a neuroendocrine chaperone that transiently interacts with prohormone convertase PC2 in the secretory pathway." Cell 78:263-273(1994) [PubMed ] [Europe PMC ] [Abstract ]
"Neuroendocrine secretory protein 7B2: structure, expression and functions." Biochem. J. 357:329-342(2001) [PubMed ] [Europe PMC ] [Abstract ]
