Secernin 1 (SCRN1)
SES1
Secernin-1 is a protein encoded by the SCRN1 gene. is an archaic English term meaning 'secrete'.Regulates exocytosis in mast cells. Increases both the extent of secretion and the sensitivity of mast cells to stimulation with calcium.Regulates exocytosis in mast cells. Increases both the extent of secretion and the sensitivity of mast cells to stimulation with calcium
Secernin 1, a novel 50-kDa cytosolic protein that appears to be involved in the regulation of exocytosis from peritoneal mast cells. Secernin 1 increases both the extent of secretion and increases the sensitivity of mast cells to stimulation with calcium.This gene likely encodes a member of the secernin family of proteins. A similar protein in rat functions in regulation of exocytosis in mast cells. Alternatively spliced transcript variants have been described.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU021Hu01 | Recombinant Secernin 1 (SCRN1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU021Hu01 | Monoclonal Antibody to Secernin 1 (SCRN1) | WB; IHC; ICC; IP. |
| PAU021Hu01 | Polyclonal Antibody to Secernin 1 (SCRN1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU021Hu01 | CLIA Kit for Secernin 1 (SCRN1) | CLIA assay for Antigen Detection |
| ELU021Hu01 | ELISA Kit for Secernin 1 (SCRN1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU021Mu01 | Recombinant Secernin 1 (SCRN1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU021Mu01 | Monoclonal Antibody to Secernin 1 (SCRN1) | WB; IHC; ICC; IP. |
| PAU021Mu01 | Polyclonal Antibody to Secernin 1 (SCRN1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU021Mu01 | CLIA Kit for Secernin 1 (SCRN1) | CLIA assay for Antigen Detection |
| ELU021Mu01 | ELISA Kit for Secernin 1 (SCRN1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU021Ra01 | Recombinant Secernin 1 (SCRN1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU021Ra01 | Monoclonal Antibody to Secernin 1 (SCRN1) | WB; IHC; ICC; IP. |
| PAU021Ra01 | Polyclonal Antibody to Secernin 1 (SCRN1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU021Ra01 | CLIA Kit for Secernin 1 (SCRN1) | CLIA assay for Antigen Detection |
| ELU021Ra01 | ELISA Kit for Secernin 1 (SCRN1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU021Ca01 | Recombinant Secernin 1 (SCRN1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU021Ca01 | Monoclonal Antibody to Secernin 1 (SCRN1) | WB; IHC; ICC; IP. |
| PAU021Ca01 | Polyclonal Antibody to Secernin 1 (SCRN1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU021Ca01 | CLIA Kit for Secernin 1 (SCRN1) | CLIA assay for Antigen Detection |
| ELU021Ca01 | ELISA Kit for Secernin 1 (SCRN1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU021Po01 | Recombinant Secernin 1 (SCRN1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU021Po01 | Monoclonal Antibody to Secernin 1 (SCRN1) | WB; IHC; ICC; IP. |
| PAU021Po01 | Polyclonal Antibody to Secernin 1 (SCRN1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU021Po01 | CLIA Kit for Secernin 1 (SCRN1) | CLIA assay for Antigen Detection |
| ELU021Po01 | ELISA Kit for Secernin 1 (SCRN1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU021Bo01 | Recombinant Secernin 1 (SCRN1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU021Bo01 | Monoclonal Antibody to Secernin 1 (SCRN1) | WB; IHC; ICC; IP. |
| PAU021Bo01 | Polyclonal Antibody to Secernin 1 (SCRN1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU021Bo01 | CLIA Kit for Secernin 1 (SCRN1) | CLIA assay for Antigen Detection |
| ELU021Bo01 | ELISA Kit for Secernin 1 (SCRN1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU021Rb01 | Recombinant Secernin 1 (SCRN1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU021Rb01 | Monoclonal Antibody to Secernin 1 (SCRN1) | WB; IHC; ICC; IP. |
| PAU021Rb01 | Polyclonal Antibody to Secernin 1 (SCRN1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU021Rb01 | CLIA Kit for Secernin 1 (SCRN1) | CLIA assay for Antigen Detection |
| ELU021Rb01 | ELISA Kit for Secernin 1 (SCRN1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPU021Mo01 | Recombinant Secernin 1 (SCRN1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAU021Mo01 | Monoclonal Antibody to Secernin 1 (SCRN1) | WB; IHC; ICC; IP. |
| PAU021Mo01 | Polyclonal Antibody to Secernin 1 (SCRN1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLU021Mo01 | CLIA Kit for Secernin 1 (SCRN1) | CLIA assay for Antigen Detection |
| ELU021Mo01 | ELISA Kit for Secernin 1 (SCRN1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Identification of secernin 1 as a novel immunotherapy target for gastric cancer using the expression profiles of cDNA microarray."
Cancer Sci. 97:411-419(2006) [PubMed] [Europe PMC] [Abstract]
"Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1."
DNA Res. 3:17-24(1996) [PubMed] [Europe PMC] [Abstract]
"Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones."
DNA Res. 9:99-106(2002) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"The DNA sequence of human chromosome 7."
Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]