Surfeit 1 (SURF1)
Surfeit Locus Protein 1
Surfeit locus protein 1 is a protein localized to the inner mitochondrial membrane and thought to be involved in the biogenesis of the cytochrome c oxidase complex. The protein is a member of the SURF1 family, which includes the related yeast protein SHY1 and rickettsial protein RP733.
The gene is located in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity, where it shares a bidirectional promoter with SURF2 on the opposite strand. Defects in this gene are a cause of Leigh syndrome, a severe neurological disorder that is commonly associated with systemic cytochrome c oxidase deficiency.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Surfeit 1 (SURF1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Surfeit 1 (SURF1) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Surfeit 1 (SURF1) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Surfeit 1 (SURF1) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Surfeit 1 (SURF1) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Surfeit 1 (SURF1) | CLIA assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Surfeit 1 (SURF1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Surfeit 1 (SURF1) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Surfeit 1 (SURF1) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Surfeit 1 (SURF1) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Surfeit 1 (SURF1) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Surfeit 1 (SURF1) | CLIA assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | T977Ra01 | Recombinant Surfeit 1 (SURF1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Surfeit 1 (SURF1) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Surfeit 1 (SURF1) | WB; IHC; ICC; IP. |
| PT977Ra01 | Polyclonal Antibody to Surfeit 1 (SURF1) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Surfeit 1 (SURF1) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Surfeit 1 (SURF1) | CLIA assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Surfeit 1 (SURF1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Surfeit 1 (SURF1) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Surfeit 1 (SURF1) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Surfeit 1 (SURF1) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Surfeit 1 (SURF1) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Surfeit 1 (SURF1) | CLIA assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Surfeit 1 (SURF1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Surfeit 1 (SURF1) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Surfeit 1 (SURF1) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Surfeit 1 (SURF1) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Surfeit 1 (SURF1) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Surfeit 1 (SURF1) | CLIA assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Surfeit 1 (SURF1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Surfeit 1 (SURF1) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Surfeit 1 (SURF1) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Surfeit 1 (SURF1) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Surfeit 1 (SURF1) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Surfeit 1 (SURF1) | CLIA assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Surfeit 1 (SURF1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Surfeit 1 (SURF1) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Surfeit 1 (SURF1) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Surfeit 1 (SURF1) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Surfeit 1 (SURF1) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Surfeit 1 (SURF1) | CLIA assay for Antigen Detection |
Organism species: Chicken (Gallus)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Surfeit 1 (SURF1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Surfeit 1 (SURF1) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Surfeit 1 (SURF1) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Surfeit 1 (SURF1) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Surfeit 1 (SURF1) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Surfeit 1 (SURF1) | CLIA assay for Antigen Detection |
Organism species: Ovis aries; Ovine (Sheep)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Surfeit 1 (SURF1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Surfeit 1 (SURF1) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Surfeit 1 (SURF1) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Surfeit 1 (SURF1) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Surfeit 1 (SURF1) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Surfeit 1 (SURF1) | CLIA assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Surfeit 1 (SURF1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Surfeit 1 (SURF1) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Surfeit 1 (SURF1) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Surfeit 1 (SURF1) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Surfeit 1 (SURF1) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Surfeit 1 (SURF1) | CLIA assay for Antigen Detection |
Organism species: Cavia (Guinea pig )
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Surfeit 1 (SURF1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Surfeit 1 (SURF1) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Surfeit 1 (SURF1) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Surfeit 1 (SURF1) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Surfeit 1 (SURF1) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Surfeit 1 (SURF1) | CLIA assay for Antigen Detection |
Organism species: Equus caballus; Equine (Horse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Surfeit 1 (SURF1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Surfeit 1 (SURF1) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Surfeit 1 (SURF1) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Surfeit 1 (SURF1) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Surfeit 1 (SURF1) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Surfeit 1 (SURF1) | CLIA assay for Antigen Detection |
Organism species: Capra hircus; Caprine (Goat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Surfeit 1 (SURF1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Surfeit 1 (SURF1) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Surfeit 1 (SURF1) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Surfeit 1 (SURF1) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Surfeit 1 (SURF1) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Surfeit 1 (SURF1) | CLIA assay for Antigen Detection |
Organism species: Pan-species (General)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Surfeit 1 (SURF1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Surfeit 1 (SURF1) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Surfeit 1 (SURF1) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Surfeit 1 (SURF1) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Surfeit 1 (SURF1) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Surfeit 1 (SURF1) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Surfeit 1 (SURF1) | CLIA assay for Antigen Detection |
Reference
"The Surf-1 and Surf-2 genes and their essential bidirectional promoter elements are conserved between mouse and human."
DNA Cell Biol. 13:1117-1126(1994) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"DNA sequence and analysis of human chromosome 9."
Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"SURF1, encoding a factor involved in the biogenesis of cytochrome c oxidase, is mutated in Leigh syndrome."
Nat. Genet. 20:337-343(1998) [PubMed] [Europe PMC] [Abstract]
"Mutations in the SURF1 gene associated with Leigh syndrome and cytochrome C oxidase deficiency."
Hum. Mutat. 17:374-381(2001) [PubMed] [Europe PMC] [Abstract]
"Missense mutations in SURF1 associated with deficient cytochrome c oxidase assembly in Leigh syndrome patients."
Hum. Genet. 106:194-205(2000) [PubMed] [Europe PMC] [Abstract]
"Two novel mutations of SURF1 in Leigh syndrome with cytochrome c oxidase deficiency."
Hum. Genet. 105:560-563(1999) [PubMed] [Europe PMC] [Abstract]
"SURF1 gene mutations in Polish patients with COX-deficient Leigh syndrome."
J. Appl. Genet. 42:103-108(2001) [PubMed] [Europe PMC] [Abstract]
"The consensus coding sequences of human breast and colorectal cancers."
Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]
"Deep sequencing reveals 50 novel genes for recessive cognitive disorders."
Nature 478:57-63(2011) [PubMed] [Europe PMC] [Abstract]
"Two Japanese patients with Leigh syndrome caused by novel SURF1 mutations."
Brain Dev. 34:861-865(2012) [PubMed] [Europe PMC] [Abstract]
"SURF1-associated leigh syndrome: A case series and novel mutations."
Hum. Mutat. 33:1192-1200(2012) [PubMed] [Europe PMC] [Abstract]