Chromogranin B (CHGB)
SCG1; CgB; SgI; Secretoneurin 1; Secretogranin 1
Chromogranin B is a tyrosine-sulfated secretory protein found in a wide variety of peptidergic endocrine cells. Chromogranin functions as a neuroendocrine secretory granule protein which may be the precursor for other biologically active peptides.Secretoneurin is involved in chemotaxis of monocytes and eosinophils (comparable in potency to IL8) and endothelial cells and in regulation of endothelial cell proliferation.
Highest secretoneurin levels are found in anterior pituitary, followed by adrenal medulla and posterior pituitary hypothalamus (2- to 6-fold lower levels in other brain regions investigated). Secretoneurin has been shown to have potent angiogenic activity in vivo in mouse cornea model and in vitro in a 3-dimensional gel.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | T969Hu01 | Recombinant Chromogranin B (CHGB) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Chromogranin B (CHGB) | Bioactivity | |
| Antibodies | MT969Hu22 | Monoclonal Antibody to Chromogranin B (CHGB) | WB; IHC; ICC; IP. |
| PT969Hu01 | Polyclonal Antibody to Chromogranin B (CHGB) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Chromogranin B (CHGB) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Chromogranin B (CHGB) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Chromogranin B (CHGB) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Chromogranin B (CHGB) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Chromogranin B (CHGB) | Flow Cytometry;ICC/IF | |
| Assay Kits | KET969Hu | ELISA Kit for Chromogranin B (CHGB) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Chromogranin B (CHGB) | CLIA assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | T969Mu01 | Recombinant Chromogranin B (CHGB) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Chromogranin B (CHGB) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Chromogranin B (CHGB) | WB; IHC; ICC; IP. |
| PT969Mu01 | Polyclonal Antibody to Chromogranin B (CHGB) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Chromogranin B (CHGB) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Chromogranin B (CHGB) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Chromogranin B (CHGB) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Chromogranin B (CHGB) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Chromogranin B (CHGB) | Flow Cytometry;ICC/IF | |
| Assay Kits | KET969Mu | ELISA Kit for Chromogranin B (CHGB) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Chromogranin B (CHGB) | CLIA assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | T969Ra01 | Recombinant Chromogranin B (CHGB) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Chromogranin B (CHGB) | Bioactivity | |
| Antibodies | MT969Ra21 | Monoclonal Antibody to Chromogranin B (CHGB) | WB; IHC; ICC; IP. |
| PT969Ra01 | Polyclonal Antibody to Chromogranin B (CHGB) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Chromogranin B (CHGB) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Chromogranin B (CHGB) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Chromogranin B (CHGB) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Chromogranin B (CHGB) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Chromogranin B (CHGB) | Flow Cytometry;ICC/IF | |
| Assay Kits | KET969Ra | ELISA Kit for Chromogranin B (CHGB) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Chromogranin B (CHGB) | CLIA assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Chromogranin B (CHGB) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Chromogranin B (CHGB) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Chromogranin B (CHGB) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Chromogranin B (CHGB) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Chromogranin B (CHGB) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Chromogranin B (CHGB) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Chromogranin B (CHGB) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Chromogranin B (CHGB) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Chromogranin B (CHGB) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Chromogranin B (CHGB) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Chromogranin B (CHGB) | CLIA assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Chromogranin B (CHGB) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Chromogranin B (CHGB) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Chromogranin B (CHGB) | WB; IHC; ICC; IP. |
| PT969Po01 | Polyclonal Antibody to Chromogranin B (CHGB) | WB; IHC; ICC; IF. | |
| LT969Po71 | Biotin Linked-Polyclonal Antibody to Chromogranin B (CHGB) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Chromogranin B (CHGB) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Chromogranin B (CHGB) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Chromogranin B (CHGB) | Flow Cytometry | |
| LT969Po81 | FITC Linked-Polyclonal Antibody to Chromogranin B (CHGB) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Chromogranin B (CHGB) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Chromogranin B (CHGB) | CLIA assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Chromogranin B (CHGB) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Chromogranin B (CHGB) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Chromogranin B (CHGB) | WB; IHC; ICC; IP. |
| PT969Bo01 | Polyclonal Antibody to Chromogranin B (CHGB) | WB; IHC; ICC; IF. | |
| LT969Bo71 | Biotin Linked-Polyclonal Antibody to Chromogranin B (CHGB) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Chromogranin B (CHGB) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Chromogranin B (CHGB) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Chromogranin B (CHGB) | Flow Cytometry | |
| LT969Bo81 | FITC Linked-Polyclonal Antibody to Chromogranin B (CHGB) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Chromogranin B (CHGB) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Chromogranin B (CHGB) | CLIA assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Chromogranin B (CHGB) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Chromogranin B (CHGB) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Chromogranin B (CHGB) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Chromogranin B (CHGB) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Chromogranin B (CHGB) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Chromogranin B (CHGB) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Chromogranin B (CHGB) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Chromogranin B (CHGB) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Chromogranin B (CHGB) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Chromogranin B (CHGB) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Chromogranin B (CHGB) | CLIA assay for Antigen Detection |
Organism species: Chicken (Gallus)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Chromogranin B (CHGB) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Chromogranin B (CHGB) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Chromogranin B (CHGB) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Chromogranin B (CHGB) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Chromogranin B (CHGB) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Chromogranin B (CHGB) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Chromogranin B (CHGB) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Chromogranin B (CHGB) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Chromogranin B (CHGB) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Chromogranin B (CHGB) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Chromogranin B (CHGB) | CLIA assay for Antigen Detection |
Organism species: Ovis aries; Ovine (Sheep)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Chromogranin B (CHGB) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Chromogranin B (CHGB) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Chromogranin B (CHGB) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Chromogranin B (CHGB) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Chromogranin B (CHGB) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Chromogranin B (CHGB) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Chromogranin B (CHGB) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Chromogranin B (CHGB) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Chromogranin B (CHGB) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Chromogranin B (CHGB) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Chromogranin B (CHGB) | CLIA assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Chromogranin B (CHGB) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Chromogranin B (CHGB) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Chromogranin B (CHGB) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Chromogranin B (CHGB) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Chromogranin B (CHGB) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Chromogranin B (CHGB) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Chromogranin B (CHGB) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Chromogranin B (CHGB) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Chromogranin B (CHGB) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Chromogranin B (CHGB) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Chromogranin B (CHGB) | CLIA assay for Antigen Detection |
Organism species: Cavia (Guinea pig )
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Chromogranin B (CHGB) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Chromogranin B (CHGB) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Chromogranin B (CHGB) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Chromogranin B (CHGB) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Chromogranin B (CHGB) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Chromogranin B (CHGB) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Chromogranin B (CHGB) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Chromogranin B (CHGB) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Chromogranin B (CHGB) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Chromogranin B (CHGB) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Chromogranin B (CHGB) | CLIA assay for Antigen Detection |
Organism species: Equus caballus; Equine (Horse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Chromogranin B (CHGB) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Chromogranin B (CHGB) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Chromogranin B (CHGB) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Chromogranin B (CHGB) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Chromogranin B (CHGB) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Chromogranin B (CHGB) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Chromogranin B (CHGB) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Chromogranin B (CHGB) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Chromogranin B (CHGB) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Chromogranin B (CHGB) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Chromogranin B (CHGB) | CLIA assay for Antigen Detection |
Organism species: Capra hircus; Caprine (Goat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Chromogranin B (CHGB) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Chromogranin B (CHGB) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Chromogranin B (CHGB) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Chromogranin B (CHGB) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Chromogranin B (CHGB) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Chromogranin B (CHGB) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Chromogranin B (CHGB) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Chromogranin B (CHGB) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Chromogranin B (CHGB) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Chromogranin B (CHGB) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Chromogranin B (CHGB) | CLIA assay for Antigen Detection |
Organism species: Pan-species (General)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Chromogranin B (CHGB) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Chromogranin B (CHGB) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Chromogranin B (CHGB) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Chromogranin B (CHGB) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Chromogranin B (CHGB) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Chromogranin B (CHGB) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Chromogranin B (CHGB) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Chromogranin B (CHGB) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Chromogranin B (CHGB) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Chromogranin B (CHGB) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Chromogranin B (CHGB) | CLIA assay for Antigen Detection |
Reference
"The primary structure of human secretogranin I (chromogranin B): comparison with chromogranin A reveals homologous terminal domains and a large intervening variable region."
EMBO J. 6:1203-1211(1987) [PubMed] [Europe PMC] [Abstract]
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"Identification of a new chromogranin B fragment (314-365) in endocrine tumors."
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"GAWK, a novel human pituitary polypeptide: isolation, immunocytochemical localization and complete amino acid sequence."
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"Chromogranin B (secretogranin I), a putative precursor of two novel pituitary peptides through processing at paired basic residues."
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"LC-MS/MS characterization of O-glycosylation sites and glycan structures of human cerebrospinal fluid glycoproteins."
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