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Fibroblast Growth Factor 21 (FGF21)
Fibroblast Growth Factor 21 (FGF21)
Fibroblast growth factor 21 is a member of the fibroblast growth factor (FGF) family. FGF21 stimulates glucose uptake in adipocytes but not in other cell types.This effect is additive to the activity of insulin. FGF21 treatment of adipocytes is associated with phosphorylation of FRS2, a protein linking FGF receptors to the Ras/MAP kinase pathway.
FGF21 injection in ob/ob mice results in an increase in Glut1 in adipose tissue. FGF21 also protects animals from diet-induced obesity when overexpressed in transgenic mice and lowers blood glucose and triglyceride levels when administered to diabetic rodents. Treatment of animals with FGF21 results in increased energy expenditure, fat utilization and lipid excretion.
Organism species: Homo sapiens (Human)
Organism species: Mus musculus (Mouse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Fibroblast Growth Factor 21 (FGF21) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Fibroblast Growth Factor 21 (FGF21) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Fibroblast Growth Factor 21 (FGF21) WB; IHC; ICC; IP.
PT909Mu02
Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) Flow Cytometry;ICC/IF
Assay Kits
KET909Mu
ELISA Kit for Fibroblast Growth Factor 21 (FGF21) Enzyme-linked immunosorbent assay for Antigen Detection
KCT909Mu
CLIA kit for Fibroblast Growth Factor 21 (FGF21) CLIA assay for Antigen Detection
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
T909Ra02
Recombinant Fibroblast Growth Factor 21 (FGF21) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Fibroblast Growth Factor 21 (FGF21) Bioactivity
Antibodies
MT909Ra21
Monoclonal Antibody to Fibroblast Growth Factor 21 (FGF21) WB; IHC; ICC; IP.
PT909Ra01
Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Fibroblast Growth Factor 21 (FGF21) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Fibroblast Growth Factor 21 (FGF21) CLIA assay for Antigen Detection
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Fibroblast Growth Factor 21 (FGF21) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Fibroblast Growth Factor 21 (FGF21) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Fibroblast Growth Factor 21 (FGF21) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Fibroblast Growth Factor 21 (FGF21) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Fibroblast Growth Factor 21 (FGF21) CLIA assay for Antigen Detection
Organism species: Sus scrofa; Porcine (Pig)
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Fibroblast Growth Factor 21 (FGF21) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Fibroblast Growth Factor 21 (FGF21) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Fibroblast Growth Factor 21 (FGF21) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Fibroblast Growth Factor 21 (FGF21) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Fibroblast Growth Factor 21 (FGF21) CLIA assay for Antigen Detection
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Fibroblast Growth Factor 21 (FGF21) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Fibroblast Growth Factor 21 (FGF21) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Fibroblast Growth Factor 21 (FGF21) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Fibroblast Growth Factor 21 (FGF21) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Fibroblast Growth Factor 21 (FGF21) CLIA assay for Antigen Detection
Organism species: Chicken (Gallus)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Fibroblast Growth Factor 21 (FGF21) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Fibroblast Growth Factor 21 (FGF21) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Fibroblast Growth Factor 21 (FGF21) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Fibroblast Growth Factor 21 (FGF21) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Fibroblast Growth Factor 21 (FGF21) CLIA assay for Antigen Detection
Organism species: Ovis aries; Ovine (Sheep)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Fibroblast Growth Factor 21 (FGF21) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Fibroblast Growth Factor 21 (FGF21) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Fibroblast Growth Factor 21 (FGF21) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Fibroblast Growth Factor 21 (FGF21) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Fibroblast Growth Factor 21 (FGF21) CLIA assay for Antigen Detection
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Fibroblast Growth Factor 21 (FGF21) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Fibroblast Growth Factor 21 (FGF21) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Fibroblast Growth Factor 21 (FGF21) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Fibroblast Growth Factor 21 (FGF21) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Fibroblast Growth Factor 21 (FGF21) CLIA assay for Antigen Detection
Organism species: Cavia (Guinea pig )
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Fibroblast Growth Factor 21 (FGF21) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Fibroblast Growth Factor 21 (FGF21) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Fibroblast Growth Factor 21 (FGF21) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Fibroblast Growth Factor 21 (FGF21) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Fibroblast Growth Factor 21 (FGF21) CLIA assay for Antigen Detection
Organism species: Equus caballus; Equine (Horse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Fibroblast Growth Factor 21 (FGF21) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Fibroblast Growth Factor 21 (FGF21) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Fibroblast Growth Factor 21 (FGF21) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Fibroblast Growth Factor 21 (FGF21) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Fibroblast Growth Factor 21 (FGF21) CLIA assay for Antigen Detection
Organism species: Capra hircus; Caprine (Goat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Fibroblast Growth Factor 21 (FGF21) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Fibroblast Growth Factor 21 (FGF21) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Fibroblast Growth Factor 21 (FGF21) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Fibroblast Growth Factor 21 (FGF21) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Fibroblast Growth Factor 21 (FGF21) CLIA assay for Antigen Detection
Organism species: Pan-species (General)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Fibroblast Growth Factor 21 (FGF21) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Fibroblast Growth Factor 21 (FGF21) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Fibroblast Growth Factor 21 (FGF21) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Fibroblast Growth Factor 21 (FGF21) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Fibroblast Growth Factor 21 (FGF21) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Fibroblast Growth Factor 21 (FGF21) CLIA assay for Antigen Detection
Reference
"Identification of a novel FGF, FGF-21, preferentially expressed in the liver." Biochim. Biophys. Acta 1492:203-206(2000) [PubMed ] [Europe PMC ] [Abstract ]
"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed ] [Europe PMC ] [Abstract ]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." Genome Res. 14:2121-2127(2004) [PubMed ] [Europe PMC ] [Abstract ]
"Signal peptide prediction based on analysis of experimentally verified cleavage sites." Protein Sci. 13:2819-2824(2004) [PubMed ] [Europe PMC ] [Abstract ]
"FGF-21 as a novel metabolic regulator." J. Clin. Invest. 115:1627-1635(2005) [PubMed ] [Europe PMC ] [Abstract ]
"Tissue-specific expression of betaKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21." J. Biol. Chem. 282:26687-26695(2007) [PubMed ] [Europe PMC ] [Abstract ]
"C-terminal tail of FGF19 determines its specificity toward Klotho co-receptors." J. Biol. Chem. 283:33304-33309(2008) [PubMed ] [Europe PMC ] [Abstract ]
"Different roles of N- and C- termini in the functional activity of FGF21." J. Cell. Physiol. 219:227-234(2009) [PubMed ] [Europe PMC ] [Abstract ]
"Fibroblast growth factor signalling: from development to cancer." Nat. Rev. Cancer 10:116-129(2010) [PubMed ] [Europe PMC ] [Abstract ]
